Project measure / variable:   Auwerx2   bw_14wks_MRI_HFD

ID, description, units MPD:114560   bw_14wks_MRI_HFD   body weight measured by EchoMRI   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight measured by EchoMRI HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means27.672   g 34.21   g
Median of the strain means23.463   g 32.625   g
SD of the strain means± 16.38 ± 16.263
Coefficient of variation (CV)0.5919 0.4754
Min–max range of strain means13.253   –   68.01   g 16.02   –   71.5   g
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 730.9498 730.9498 118.5774 < 0.0001
strain 7 3514.5698 502.0814 81.4495 < 0.0001
sex:strain 7 183.4192 26.2027 4.2507 0.0008
Residuals 56 345.2023 6.1643


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.078 0.78465   5 0.3509 0.034 22.12, 24.27 -0.28
129S1/SvImJ m 32.625 1.393   2   0.985 0.0427 31.64, 33.61 -0.1
A/J f 22.667 1.8409   4 0.92046 0.0812 21.11, 25.29 -0.31
A/J m 28.566 1.5908   5 0.71144 0.0557 26.17, 30.44 -0.35
C57BL/6J f 23.463 1.2456   3 0.71913 0.0531 22.54, 24.88 -0.26
C57BL/6J m 38.553 2.5277   4 1.2639 0.0656 35.79, 41.26 0.27
CAST/EiJ f 13.344 0.78691   5 0.35192 0.059 12.53, 14.58 -0.87
CAST/EiJ m 17.58 1.0324   2   0.73 0.0587 16.85, 18.31 -1.02
DBA/2J f 33.182 2.4948   5 1.1157 0.0752 29.54, 35.56 0.34
DBA/2J m 40.488 2.2467   5 1.0048 0.0555 37.55, 43.65 0.39
NOD/ShiLtJ f 27.808 4.5379   10 1.435 0.1632 22.85, 37.2 0.01
NOD/ShiLtJ m 33.28 1.7631   5 0.78849 0.053 31.27, 35.95 -0.06
NZO/HlLtJ f 68.01 2.4342   5 1.0886 0.0358 65.4, 71.45 2.46
NZO/HlLtJ m 71.5 0.0   1   0.0 0.0 71.5, 71.5 2.29
PWK/PhJ f 24.24 2.4093   4 1.2047 0.0994 21.05, 26.86 -0.21
PWK/PhJ m 29.276 2.7063   5 1.2103 0.0924 25.63, 33.25 -0.3
WSB/EiJ f 13.253 0.81525   3 0.47069 0.0615 12.45, 14.08 -0.88
WSB/EiJ m 16.02 0.97473   5 0.43591 0.0608 15.01, 17.23 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.078 1.1103446912 25.3022876974 20.8537123026
129S1/SvImJ m 32.625 1.7556091061 36.1419076477 29.1080923523
A/J f 22.6675 1.241403104 25.1543292465 20.1806707535
A/J m 28.566 1.1103446912 30.7902876974 26.3417123026
C57BL/6J f 23.4633333333 1.4334488326 26.3348764031 20.5917902636
C57BL/6J m 38.5525 1.241403104 41.0393292465 36.0656707535
CAST/EiJ f 13.344 1.1103446912 15.5682876974 11.1197123026
CAST/EiJ m 17.58 1.7556091061 21.0969076477 14.0630923523
DBA/2J f 33.182 1.1103446912 35.4062876974 30.9577123026
DBA/2J m 40.488 1.1103446912 42.7122876974 38.2637123026
NOD/ShiLtJ f 27.808 0.7851322606 29.3808089142 26.2351910858
NOD/ShiLtJ m 33.28 1.1103446912 35.5042876974 31.0557123026
PWK/PhJ f 24.24 1.241403104 26.7268292465 21.7531707535
PWK/PhJ m 29.276 1.1103446912 31.5002876974 27.0517123026
WSB/EiJ f 13.2533333333 1.4334488326 16.1248764031 10.3817902636
WSB/EiJ m 16.02 1.1103446912 18.2442876974 13.7957123026


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 27.8515 1.0386323539 29.9321306233 25.7708693767
A/J both 25.61675 0.8327585184 27.2849657731 23.9485342269
C57BL/6J both 31.0079166667 0.948137282 32.9072638771 29.1085694563
CAST/EiJ both 15.462 1.0386323539 17.5426306233 13.3813693767
DBA/2J both 36.835 0.7851322606 38.4078089142 35.2621910858
NOD/ShiLtJ both 30.544 0.679944483 31.906092475 29.181907525
PWK/PhJ both 26.758 0.8327585184 28.4262157731 25.0897842269
WSB/EiJ both 14.6366666667 0.906592644 16.4527899666 12.8205433667




  GWAS USING LINEAR MIXED MODELS