Project measure / variable:   Auwerx2   bw_21wks_HFD

ID, description, units MPD:114558   bw_21wks_HFD   body weight at 21 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 21 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means32.426   g 36.929   g
Median of the strain means26.92   g 34.64   g
SD of the strain means± 20.791 ± 17.84
Coefficient of variation (CV)0.6412 0.4831
Min–max range of strain means13.814   –   83.23   g 17.39   –   76.01   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 585.4367 585.4367 72.763 < 0.0001
strain 7 5439.6321 777.0903 96.5833 < 0.0001
sex:strain 7 357.1331 51.019 6.3411 < 0.0001
Residuals 52 418.3819 8.0458


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 24.278 0.9058   5 0.40509 0.0373 23.37, 25.59 -0.39
129S1/SvImJ m 34.64 1.2869   2   0.91 0.0372 33.73, 35.55 -0.13
A/J f 24.828 2.2428   4 1.1214 0.0903 22.96, 27.95 -0.37
A/J m 29.718 2.3814   5 1.065 0.0801 27.23, 32.72 -0.4
C57BL/6J f 31.71 5.204   3 3.0045 0.1641 26.94, 37.26 -0.03
C57BL/6J m 48.93 3.725   4 1.8625 0.0761 43.54, 51.48 0.67
CAST/EiJ f 13.814 0.94145   5 0.42103 0.0682 12.65, 15.24 -0.9
CAST/EiJ m 19.07 2.0223   2   1.43 0.106 17.64, 20.5 -1.0
DBA/2J f 39.996 3.8571   5 1.725 0.0964 35.22, 44.89 0.36
DBA/2J m 43.004 3.445   5 1.5406 0.0801 38.78, 47.69 0.34
NOD/ShiLtJ f 32.477 3.4582   6 1.4118 0.1065 30.14, 39.16 0.0
NOD/ShiLtJ m 35.496 1.7378   5 0.77715 0.049 34.36, 38.45 -0.08
NZO/HlLtJ f 83.23 1.9498   5 0.87198 0.0234 80.88, 85.42 2.44
NZO/HlLtJ m 76.01 0.0   1   0.0 0.0 76.01, 76.01 2.19
PWK/PhJ f 26.92 1.9949   4 0.99743 0.0741 24.94, 29.52 -0.26
PWK/PhJ m 28.102 4.4119   5 1.9731 0.157 22.51, 33.56 -0.49
WSB/EiJ f 14.58 0.47791   3 0.27592 0.0328 14.16, 15.1 -0.86
WSB/EiJ m 17.39 0.88482   5 0.3957 0.0509 16.55, 18.68 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 24.278 1.2685272022 26.8234860575 21.7325139425
129S1/SvImJ m 34.64 2.0057176165 38.664766847 30.615233153
A/J f 24.8275 1.4182565278 27.6734399302 21.9815600698
A/J m 29.718 1.2685272022 32.2634860575 27.1725139425
C57BL/6J f 31.71 1.6376615762 34.9962083696 28.4237916304
C57BL/6J m 48.93 1.4182565278 51.7759399302 46.0840600698
CAST/EiJ f 13.814 1.2685272022 16.3594860575 11.2685139425
CAST/EiJ m 19.07 2.0057176165 23.094766847 15.045233153
DBA/2J f 39.996 1.2685272022 42.5414860575 37.4505139425
DBA/2J m 43.004 1.2685272022 45.5494860575 40.4585139425
NOD/ShiLtJ f 32.4766666667 1.1580016058 34.8003668892 30.1529664441
NOD/ShiLtJ m 35.496 1.2685272022 38.0414860575 32.9505139425
PWK/PhJ f 26.92 1.4182565278 29.7659399302 24.0740600698
PWK/PhJ m 28.102 1.2685272022 30.6474860575 25.5565139425
WSB/EiJ f 14.58 1.6376615762 17.8662083696 11.2937916304
WSB/EiJ m 17.39 1.2685272022 19.9354860575 14.8445139425


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.459 1.1865985441 31.8400841775 27.0779158225
A/J both 27.27275 0.9513954017 29.1818645431 25.3636354569
C57BL/6J both 40.32 1.0832113156 42.4936225256 38.1463774744
CAST/EiJ both 16.442 1.1865985441 18.8230841775 14.0609158225
DBA/2J both 41.5 0.8969841868 43.2999304527 39.7000695473
NOD/ShiLtJ both 33.9863333333 0.8587969757 35.7096355408 32.2630311259
PWK/PhJ both 27.511 0.9513954017 29.4201145431 25.6018854569
WSB/EiJ both 15.985 1.0357481234 18.0633806628 13.9066193372




  GWAS USING LINEAR MIXED MODELS