Project measure / variable:   Auwerx2   bw_14wks_HFD

ID, description, units MPD:114544   bw_14wks_HFD   body weight at 14 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 14 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means27.728   g 33.987   g
Median of the strain means23.22   g 32.625   g
SD of the strain means± 16.499 ± 16.274
Coefficient of variation (CV)0.595 0.4788
Min–max range of strain means12.693   –   68.02   g 16.02   –   71.5   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 691.3368 691.3368 142.6165 < 0.0001
strain 7 3549.3565 507.0509 104.6 < 0.0001
sex:strain 7 205.7633 29.3948 6.0639 < 0.0001
Residuals 52 252.0712 4.8475


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 22.668 0.92001   5 0.41144 0.0406 21.58, 24.01 -0.31
129S1/SvImJ m 32.625 1.393   2   0.985 0.0427 31.64, 33.61 -0.08
A/J f 22.415 1.872   4 0.93599 0.0835 20.54, 24.97 -0.32
A/J m 28.984 1.766   5 0.78978 0.0609 26.45, 31.05 -0.31
C57BL/6J f 23.22 1.5476   3 0.89353 0.0667 21.94, 24.94 -0.27
C57BL/6J m 37.527 2.4233   4 1.2116 0.0646 35.08, 40.24 0.22
CAST/EiJ f 13.344 0.78691   5 0.35192 0.059 12.53, 14.58 -0.87
CAST/EiJ m 17.58 1.0324   2   0.73 0.0587 16.85, 18.31 -1.01
DBA/2J f 32.664 3.0792   5 1.3771 0.0943 28.26, 36.21 0.3
DBA/2J m 40.488 2.2467   5 1.0048 0.0555 37.55, 43.65 0.4
NOD/ShiLtJ f 30.617 3.6373   6 1.4849 0.1188 27.1, 37.2 0.18
NOD/ShiLtJ m 33.28 1.7631   5 0.78849 0.053 31.27, 35.95 -0.04
NZO/HlLtJ f 68.02 2.4307   5 1.0871 0.0357 65.4, 71.45 2.44
NZO/HlLtJ m 71.5 0.0   1   0.0 0.0 71.5, 71.5 2.31
PWK/PhJ f 23.91 2.6864   4 1.3432 0.1124 20.19, 26.55 -0.23
PWK/PhJ m 27.882 2.9354   5 1.3128 0.1053 23.81, 32.09 -0.38
WSB/EiJ f 12.693 0.77106   3 0.44517 0.0607 11.84, 13.34 -0.91
WSB/EiJ m 16.02 0.97473   5 0.43591 0.0608 15.01, 17.23 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 22.668 0.9846343035 24.6438132792 20.6921867208
129S1/SvImJ m 32.625 1.5568435306 35.7490350967 29.5009649033
A/J f 22.415 1.1008546178 24.6240264015 20.2059735985
A/J m 28.984 0.9846343035 30.9598132792 27.0081867208
C57BL/6J f 23.22 1.2711574198 25.7707639752 20.6692360248
C57BL/6J m 37.5275 1.1008546178 39.7365264015 35.3184735985
CAST/EiJ f 13.344 0.9846343035 15.3198132792 11.3681867208
CAST/EiJ m 17.58 1.5568435306 20.7040350967 14.4559649033
DBA/2J f 32.664 0.9846343035 34.6398132792 30.6881867208
DBA/2J m 40.488 0.9846343035 42.4638132792 38.5121867208
NOD/ShiLtJ f 30.6166666667 0.8988440315 32.4203291707 28.8130041626
NOD/ShiLtJ m 33.28 0.9846343035 35.2558132792 31.3041867208
PWK/PhJ f 23.91 1.1008546178 26.1190264015 21.7009735985
PWK/PhJ m 27.882 0.9846343035 29.8578132792 25.9061867208
WSB/EiJ f 12.6933333333 1.2711574198 15.2440973085 10.1425693582
WSB/EiJ m 16.02 0.9846343035 17.9958132792 14.0441867208


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 27.6465 0.9210410537 29.4947040877 25.7982959123
A/J both 25.6995 0.7384757276 27.1813599594 24.2176400406
C57BL/6J both 30.37375 0.8407916025 32.0609217829 28.6865782171
CAST/EiJ both 15.462 0.9210410537 17.3102040877 13.6137959123
DBA/2J both 36.576 0.696241593 37.9731109681 35.1788890319
NOD/ShiLtJ both 31.9483333333 0.6666005746 33.2859652467 30.61070142
PWK/PhJ both 25.896 0.7384757276 27.3778599594 24.4141400406
WSB/EiJ both 14.3566666667 0.8039505422 15.9699114537 12.7434218797




  GWAS USING LINEAR MIXED MODELS