Project measure / variable:   Auwerx2   bw_11wks_HFD

ID, description, units MPD:114538   bw_11wks_HFD   body weight at 11 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 11wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 11 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means24.608   g 30.332   g
Median of the strain means21.73   g 30.814   g
SD of the strain means± 12.784 ± 14.543
Coefficient of variation (CV)0.5195 0.4795
Min–max range of strain means12.564   –   55.53   g 14.896   –   63.73   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 457.1849 457.1849 106.5893 < 0.0001
strain 7 2654.3487 379.1927 88.406 < 0.0001
sex:strain 7 136.1643 19.452 4.5351 0.0005
Residuals 52 223.0394 4.2892


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.73 0.78086   5 0.34921 0.0359 20.68, 22.77 -0.23
129S1/SvImJ m 31.17 0.84853   2   0.6 0.0272 30.57, 31.77 0.06
A/J f 21.522 1.6115   4 0.80573 0.0749 20.48, 23.88 -0.24
A/J m 26.752 1.53   5 0.68423 0.0572 24.51, 28.15 -0.25
C57BL/6J f 22.123 0.60929   3 0.35177 0.0275 21.69, 22.82 -0.19
C57BL/6J m 31.918 1.6271   4 0.81355 0.051 30.37, 34.21 0.11
CAST/EiJ f 12.564 0.73643   5 0.32934 0.0586 11.53, 13.6 -0.94
CAST/EiJ m 15.38 0.74953   2   0.53 0.0487 14.85, 15.91 -1.03
DBA/2J f 27.926 2.6715   5 1.1947 0.0957 25.77, 32.14 0.26
DBA/2J m 36.088 3.0876   5 1.3808 0.0856 32.19, 40.53 0.4
NOD/ShiLtJ f 27.588 3.4482   6 1.4077 0.125 23.82, 33.88 0.23
NOD/ShiLtJ m 30.814 1.4729   5 0.65872 0.0478 29.3, 32.92 0.03
NZO/HlLtJ f 55.53 2.6037   5 1.1644 0.0469 53.57, 59.77 2.42
NZO/HlLtJ m 63.73 0.0   1   0.0 0.0 63.73, 63.73 2.3
PWK/PhJ f 19.6 2.3982   4 1.1991 0.1224 16.37, 22.15 -0.39
PWK/PhJ m 22.242 2.9545   5 1.3213 0.1328 18.19, 26.28 -0.56
WSB/EiJ f 12.89 0.41328   3 0.23861 0.0321 12.43, 13.23 -0.92
WSB/EiJ m 14.896 0.99866   5 0.44662 0.067 13.72, 16.01 -1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.73 0.9261986413 23.5885535443 19.8714464557
129S1/SvImJ m 31.17 1.4644486361 34.1086311768 28.2313688232
A/J f 21.5225 1.0355215613 23.6004260325 19.4445739675
A/J m 26.752 0.9261986413 28.6105535443 24.8934464557
C57BL/6J f 22.1233333333 1.1957173043 24.5227156418 19.7239510249
C57BL/6J m 31.9175 1.0355215613 33.9954260325 29.8395739675
CAST/EiJ f 12.564 0.9261986413 14.4225535443 10.7054464557
CAST/EiJ m 15.38 1.4644486361 18.3186311768 12.4413688232
DBA/2J f 27.926 0.9261986413 29.7845535443 26.0674464557
DBA/2J m 36.088 0.9261986413 37.9465535443 34.2294464557
NOD/ShiLtJ f 27.5883333333 0.8454998143 29.2849528343 25.8917138324
NOD/ShiLtJ m 30.814 0.9261986413 32.6725535443 28.9554464557
PWK/PhJ f 19.6 1.0355215613 21.6779260325 17.5220739675
PWK/PhJ m 22.242 0.9261986413 24.1005535443 20.3834464557
WSB/EiJ f 12.89 1.1957173043 15.2893823084 10.4906176916
WSB/EiJ m 14.896 0.9261986413 16.7545535443 13.0374464557


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.45 0.8663794969 28.1885176495 24.7114823505
A/J both 24.13725 0.6946489809 25.5311651583 22.7433348417
C57BL/6J both 27.0204166667 0.7908926564 28.6074588887 25.4333744446
CAST/EiJ both 13.972 0.8663794969 15.7105176495 12.2334823505
DBA/2J both 32.007 0.65492134 33.3211958144 30.6928041856
NOD/ShiLtJ both 29.2011666667 0.6270394443 30.4594133643 27.9429199691
PWK/PhJ both 20.921 0.6946489809 22.3149151583 19.5270848417
WSB/EiJ both 13.893 0.7562380239 15.4105026144 12.3754973856




  GWAS USING LINEAR MIXED MODELS