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Project measure / variable:   Project1061   cohort_nicotine

ID, description, units MPD:113862   cohort_nicotine   cohort    nicotine   measure and covariate
Data set, strains Project1061   BXD w/par   31 strains     sex: both
Procedure fear conditioning test
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1061 - cohort nicotine



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains31 strains
Mean of the strain means16.372   None 15.119   None
Median of the strain means15.125   None 13.125   None
SD of the strain means± 5.6504 ± 6.6328
Coefficient of variation (CV)0.3451 0.4387
Min–max range of strain means4.0   –   34.0   None 5.6   –   34.0   None
Mean sample size per strain8.1   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 199.436 199.436 3.2472 0.0722
strain 30 15942.3582 531.4119 8.6525 < 0.0001
sex:strain 30 2594.3006 86.4767 1.408 0.0773
Residuals 446 27391.9445 61.4169


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD102/RwwJ f 20.625 9.2108   8 3.2565 0.4466 1.0, 26.0 0.75
BXD102/RwwJ m 20.75 9.2852   8 3.2828 0.4475 1.0, 26.0 0.85
BXD124/RwwJ f 14.125 10.508   8 3.715 0.7439 7.0, 34.0 -0.4
BXD124/RwwJ m 10.75 6.9437   8 2.455 0.6459 7.0, 22.0 -0.66
BXD13/TyJ f 22.375 12.614   8 4.4599 0.5638 2.0, 35.0 1.06
BXD13/TyJ m 23.875 9.848   8 3.4818 0.4125 2.0, 32.0 1.32
BXD154/RwwJ f 15.625 5.7802   8 2.0436 0.3699 4.0, 20.0 -0.13
BXD154/RwwJ m 13.889 6.4118   9 2.1373 0.4616 4.0, 26.0 -0.19
BXD161/RwwJ f 7.875 6.7281   8 2.3788 0.8544 3.0, 16.0 -1.5
BXD161/RwwJ m 6.25 6.0178   8 2.1276 0.9629 3.0, 16.0 -1.34
BXD18/TyJ f 14.375 9.7678   8 3.4535 0.6795 1.0, 23.0 -0.35
BXD18/TyJ m 17.889 11.868   9 3.9562 0.6635 1.0, 30.0 0.42
BXD21/TyJ f 11.125 8.2191   8 2.9059 0.7388 1.0, 23.0 -0.93
BXD21/TyJ m 10.625 8.3141   8 2.9395 0.7825 1.0, 23.0 -0.68
BXD31/TyJ f 25.0 6.4807   8 2.2913 0.2592 9.0, 28.0 1.53
BXD31/TyJ m 25.625 6.7175   8 2.375 0.2621 9.0, 28.0 1.58
BXD32/TyJ f 13.875 6.6855   8 2.3637 0.4818 1.0, 22.0 -0.44
BXD32/TyJ m 10.857 6.176   7 2.3343 0.5688 1.0, 22.0 -0.64
BXD33/TyJ f 18.75 4.9497   8 1.75 0.264 17.0, 31.0 0.42
BXD33/TyJ m 11.727 1.009   11 0.30424 0.086 11.0, 13.0 -0.51
BXD34/TyJ f 14.2 5.2026   10 1.6452 0.3664 7.0, 18.0 -0.38
BXD34/TyJ m 11.5 5.4772   8 1.9365 0.4763 7.0, 18.0 -0.55
BXD38/TyJ f 14.222 5.5628   9 1.8543 0.3911 2.0, 18.0 -0.38
BXD38/TyJ m 11.25 5.5742   8 1.9708 0.4955 2.0, 18.0 -0.58
BXD39/TyJ f 13.125 7.6986   8 2.7219 0.5866 1.0, 20.0 -0.57
BXD39/TyJ m 13.125 7.6986   8 2.7219 0.5866 1.0, 20.0 -0.3
BXD40/TyJ f 11.5 5.8797   8 2.0788 0.5113 2.0, 18.0 -0.86
BXD40/TyJ m 9.75 5.4968   8 1.9434 0.5638 2.0, 18.0 -0.81
BXD45/RwwJ f 4.0 0.0   8 0.0 0.0 4.0, 4.0 -2.19
BXD45/RwwJ m 9.5 5.8797   8 2.0788 0.6189 4.0, 15.0 -0.85
BXD48a/RwwJ f 19.75 9.4226   8 3.3314 0.4771 11.0, 30.0 0.6
BXD48a/RwwJ m 17.5 9.0554   8 3.2016 0.5175 11.0, 31.0 0.36
BXD55/RwwJ f 13.875 4.1897   8 1.4813 0.302 11.0, 24.0 -0.44
BXD55/RwwJ m 21.556 6.6353   9 2.2118 0.3078 11.0, 32.0 0.97
BXD56/RwwJ f 11.875 8.0078   8 2.8312 0.6743 1.0, 19.0 -0.8
BXD56/RwwJ m 11.875 8.0078   8 2.8312 0.6743 1.0, 19.0 -0.49
BXD64/RwwJ f 10.875 4.9696   8 1.757 0.457 5.0, 15.0 -0.97
BXD64/RwwJ m 7.875 3.4821   8 1.2311 0.4422 5.0, 12.0 -1.09
BXD67/RwwJ f 12.0 6.6762   8 2.3604 0.5563 5.0, 21.0 -0.77
BXD67/RwwJ m 11.0 7.0912   8 2.5071 0.6447 5.0, 21.0 -0.62
BXD73a/RwwJ f 22.375 11.401   8 4.0309 0.5095 2.0, 29.0 1.06
BXD73a/RwwJ m 5.6 1.2649   10 0.4 0.2259 2.0, 6.0 -1.44
BXD74/RwwJ f 18.125 11.025   8 3.898 0.6083 6.0, 32.0 0.31
BXD74/RwwJ m 10.75 10.166   8 3.5944 0.9457 5.0, 32.0 -0.66
BXD78 f 15.125 6.9166   8 2.4454 0.4573 1.0, 20.0 -0.22
BXD78 m 13.125 6.6211   8 2.3409 0.5045 1.0, 20.0 -0.3
BXD84/RwwJ f 20.0 8.8479   8 3.1282 0.4424 1.0, 25.0 0.64
BXD84/RwwJ m 15.0 8.9762   8 3.1736 0.5984 1.0, 25.0 -0.02
BXD85/RwwJ f 17.125 6.5343   8 2.3102 0.3816 4.0, 22.0 0.13
BXD85/RwwJ m 17.125 6.5343   8 2.3102 0.3816 4.0, 22.0 0.3
BXD89/RwwJ f 21.75 8.7627   8 3.0981 0.4029 4.0, 27.0 0.95
BXD89/RwwJ m 24.125 8.2365   8 2.912 0.3414 4.0, 30.0 1.36
BXD90/RwwJ f 18.5 8.9762   8 3.1736 0.4852 12.0, 30.0 0.38
BXD90/RwwJ m 25.75 7.8695   8 2.7823 0.3056 13.0, 30.0 1.6
BXD98/RwwJ f 16.0 13.898   8 4.9135 0.8686 3.0, 29.0 -0.07
BXD98/RwwJ m 16.0 13.898   8 4.9135 0.8686 3.0, 29.0 0.13
BXD99/RwwJ f 21.0 10.967   8 3.8776 0.5223 2.0, 33.0 0.82
BXD99/RwwJ m 20.3 8.4859   10 2.6835 0.418 2.0, 26.0 0.78
C57BL/6J f 14.375 10.127   8 3.5804 0.7045 1.0, 33.0 -0.35
C57BL/6J m 9.75 7.2457   8 2.5617 0.7431 1.0, 15.0 -0.81
DBA/2J f 34.0 0.0   8 0.0 0.0 34.0, 34.0 3.12
DBA/2J m 34.0 0.0   8 0.0 0.0 34.0, 34.0 2.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD102/RwwJ f 20.625 2.7707606347 26.0703681077 15.1796318923
BXD102/RwwJ m 20.75 2.7707606347 26.1953681077 15.3046318923
BXD124/RwwJ f 14.125 2.7707606347 19.5703681077 8.6796318923
BXD124/RwwJ m 10.75 2.7707606347 16.1953681077 5.3046318923
BXD13/TyJ f 22.375 2.7707606347 27.8203681077 16.9296318923
BXD13/TyJ m 23.875 2.7707606347 29.3203681077 18.4296318923
BXD154/RwwJ f 15.625 2.7707606347 21.0703681077 10.1796318923
BXD154/RwwJ m 13.8888888889 2.6122981784 19.0228311756 8.7549466022
BXD161/RwwJ f 7.875 2.7707606347 13.3203681077 2.4296318923
BXD161/RwwJ m 6.25 2.7707606347 11.6953681077 0.8046318923
BXD18/TyJ f 14.375 2.7707606347 19.8203681077 8.9296318923
BXD18/TyJ m 17.8888888889 2.6122981784 23.0228311756 12.7549466022
BXD21/TyJ f 11.125 2.7707606347 16.5703681077 5.6796318923
BXD21/TyJ m 10.625 2.7707606347 16.0703681077 5.1796318923
BXD31/TyJ f 25.0 2.7707606347 30.4453681077 19.5546318923
BXD31/TyJ m 25.625 2.7707606347 31.0703681077 20.1796318923
BXD32/TyJ f 13.875 2.7707606347 19.3203681077 8.4296318923
BXD32/TyJ m 10.8571428571 2.962067713 16.6784862297 5.0357994846
BXD33/TyJ f 18.75 2.7707606347 24.1953681077 13.3046318923
BXD33/TyJ m 11.7272727273 2.3629126086 16.3710982528 7.0834472018
BXD34/TyJ f 14.2 2.4782436514 19.0704853005 9.3295146995
BXD34/TyJ m 11.5 2.7707606347 16.9453681077 6.0546318923
BXD38/TyJ f 14.2222222222 2.6122981784 19.3561645089 9.0882799356
BXD38/TyJ m 11.25 2.7707606347 16.6953681077 5.8046318923
BXD39/TyJ f 13.125 2.7707606347 18.5703681077 7.6796318923
BXD39/TyJ m 13.125 2.7707606347 18.5703681077 7.6796318923
BXD40/TyJ f 11.5 2.7707606347 16.9453681077 6.0546318923
BXD40/TyJ m 9.75 2.7707606347 15.1953681077 4.3046318923
BXD45/RwwJ f 4.0 2.7707606347 9.4453681077 -1.4453681077
BXD45/RwwJ m 9.5 2.7707606347 14.9453681077 4.0546318923
BXD48a/RwwJ f 19.75 2.7707606347 25.1953681077 14.3046318923
BXD48a/RwwJ m 17.5 2.7707606347 22.9453681077 12.0546318923
BXD55/RwwJ f 13.875 2.7707606347 19.3203681077 8.4296318923
BXD55/RwwJ m 21.5555555556 2.6122981784 26.6894978422 16.4216132689
BXD56/RwwJ f 11.875 2.7707606347 17.3203681077 6.4296318923
BXD56/RwwJ m 11.875 2.7707606347 17.3203681077 6.4296318923
BXD64/RwwJ f 10.875 2.7707606347 16.3203681077 5.4296318923
BXD64/RwwJ m 7.875 2.7707606347 13.3203681077 2.4296318923
BXD67/RwwJ f 12.0 2.7707606347 17.4453681077 6.5546318923
BXD67/RwwJ m 11.0 2.7707606347 16.4453681077 5.5546318923
BXD73a/RwwJ f 22.375 2.7707606347 27.8203681077 16.9296318923
BXD73a/RwwJ m 5.6 2.4782436514 10.4704853005 0.7295146995
BXD74/RwwJ f 18.125 2.7707606347 23.5703681077 12.6796318923
BXD74/RwwJ m 10.75 2.7707606347 16.1953681077 5.3046318923
BXD78 f 15.125 2.7707606347 20.5703681077 9.6796318923
BXD78 m 13.125 2.7707606347 18.5703681077 7.6796318923
BXD84/RwwJ f 20.0 2.7707606347 25.4453681077 14.5546318923
BXD84/RwwJ m 15.0 2.7707606347 20.4453681077 9.5546318923
BXD85/RwwJ f 17.125 2.7707606347 22.5703681077 11.6796318923
BXD85/RwwJ m 17.125 2.7707606347 22.5703681077 11.6796318923
BXD89/RwwJ f 21.75 2.7707606347 27.1953681077 16.3046318923
BXD89/RwwJ m 24.125 2.7707606347 29.5703681077 18.6796318923
BXD90/RwwJ f 18.5 2.7707606347 23.9453681077 13.0546318923
BXD90/RwwJ m 25.75 2.7707606347 31.1953681077 20.3046318923
BXD98/RwwJ f 16.0 2.7707606347 21.4453681077 10.5546318923
BXD98/RwwJ m 16.0 2.7707606347 21.4453681077 10.5546318923
BXD99/RwwJ f 21.0 2.7707606347 26.4453681077 15.5546318923
BXD99/RwwJ m 20.3 2.4782436514 25.1704853005 15.4295146995
C57BL/6J f 14.375 2.7707606347 19.8203681077 8.9296318923
C57BL/6J m 9.75 2.7707606347 15.1953681077 4.3046318923
DBA/2J f 34.0 2.7707606347 39.4453681077 28.5546318923
DBA/2J m 34.0 2.7707606347 39.4453681077 28.5546318923


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD102/RwwJ both 20.6875 1.9592236338 24.537956715 16.837043285
BXD124/RwwJ both 12.4375 1.9592236338 16.287956715 8.587043285
BXD13/TyJ both 23.125 1.9592236338 26.975456715 19.274543285
BXD154/RwwJ both 14.7569444444 1.9040231267 18.4989157575 11.0149731314
BXD161/RwwJ both 7.0625 1.9592236338 10.912956715 3.212043285
BXD18/TyJ both 16.1319444444 1.9040231267 19.8739157575 12.3899731314
BXD21/TyJ both 10.875 1.9592236338 14.725456715 7.024543285
BXD31/TyJ both 25.3125 1.9592236338 29.162956715 21.462043285
BXD32/TyJ both 12.3660714286 2.0279891291 16.3516727787 8.3804700784
BXD33/TyJ both 15.2386363636 1.8207464466 18.8169442507 11.6603284765
BXD34/TyJ both 12.85 1.8586827385 16.5028639754 9.1971360246
BXD38/TyJ both 12.7361111111 1.9040231267 16.4780824242 8.9941397981
BXD39/TyJ both 13.125 1.9592236338 16.975456715 9.274543285
BXD40/TyJ both 10.625 1.9592236338 14.475456715 6.774543285
BXD45/RwwJ both 6.75 1.9592236338 10.600456715 2.899543285
BXD48a/RwwJ both 18.625 1.9592236338 22.475456715 14.774543285
BXD55/RwwJ both 17.7152777778 1.9040231267 21.4572490908 13.9733064647
BXD56/RwwJ both 11.875 1.9592236338 15.725456715 8.024543285
BXD64/RwwJ both 9.375 1.9592236338 13.225456715 5.524543285
BXD67/RwwJ both 11.5 1.9592236338 15.350456715 7.649543285
BXD73a/RwwJ both 13.9875 1.8586827385 17.6403639754 10.3346360246
BXD74/RwwJ both 14.4375 1.9592236338 18.287956715 10.587043285
BXD78 both 14.125 1.9592236338 17.975456715 10.274543285
BXD84/RwwJ both 17.5 1.9592236338 21.350456715 13.649543285
BXD85/RwwJ both 17.125 1.9592236338 20.975456715 13.274543285
BXD89/RwwJ both 22.9375 1.9592236338 26.787956715 19.087043285
BXD90/RwwJ both 22.125 1.9592236338 25.975456715 18.274543285
BXD98/RwwJ both 16.0 1.9592236338 19.850456715 12.149543285
BXD99/RwwJ both 20.65 1.8586827385 24.3028639754 16.9971360246
C57BL/6J both 12.0625 1.9592236338 15.912956715 8.212043285
DBA/2J both 34.0 1.9592236338 37.850456715 30.149543285




  GWAS USING LINEAR MIXED MODELS