Project measure / variable:   Graham3   ics_CD4_pos_Tbet_pos

ID, description, units MPD:113845   ics_CD4_pos_Tbet_pos   percentage of splenic CD4+ T cells that are Tbet+ (transcription factor) by intracellular staining following stimulation with anti-CD3 and anti-CD28   [%]  
Data set, strains Graham3   CC RIX   92 strains     sex: m     age: 8-10wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Graham3 - percentage of splenic CD4+ T cells that are Tbet+ (transcription factor) by intracellular staining following stimulation with anti-CD3 and anti-CD28



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested92 strains
Mean of the strain means3.0152   %
Median of the strain means1.8336   %
SD of the strain means± 3.9218
Coefficient of variation (CV)1.3007
Min–max range of strain means0.10993   –   25.467   %
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 91 5819.2053 63.9473 4.3617 < 0.0001
Residuals 296 4339.6758 14.6611


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(001 x 055) m 0.41617 0.24576   6 0.10033 0.5905 0.134, 0.721 -0.66
RIX:CC(002 x 011) m 1.1378 1.0486   5 0.46896 0.9216 0.484, 2.99 -0.48
RIX:CC(002 x 021) m 1.4287 0.57446   3 0.33167 0.4021 0.826, 1.97 -0.4
RIX:CC(003 x 051) m 0.58467 0.35731   6 0.14587 0.6111 0.26, 1.1 -0.62
RIX:CC(003 x 062) m 4.4183 4.9881   6 2.0364 1.1289 0.626, 11.6 0.36
RIX:CC(005 x 001) m 0.79533 0.66657   3 0.38484 0.8381 0.337, 1.56 -0.57
RIX:CC(005 x 038) m 1.88 1.0315   3 0.59551 0.5486 1.15, 3.06 -0.29
RIX:CC(005 x 040) m 3.207 2.4239   6 0.98957 0.7558 0.367, 6.17 0.05
RIX:CC(006 x 007) m 2.4112 1.6249   6 0.66336 0.6739 0.647, 5.08 -0.15
RIX:CC(006 x 039) m 0.823 0.22651   3 0.13078 0.2752 0.625, 1.07 -0.56
RIX:CC(007 x 070) m 0.70967 0.41994   3 0.24245 0.5917 0.412, 1.19 -0.59
RIX:CC(008 x 009) m 1.7177 0.92034   3 0.53136 0.5358 0.983, 2.75 -0.33
RIX:CC(008 x 010) m 8.5133 4.4958   3 2.5957 0.5281 5.73, 13.7 1.4
RIX:CC(008 x 018) m 0.77733 0.21653   3 0.12501 0.2786 0.543, 0.97 -0.57
RIX:CC(009 x 040) m 1.8492 2.3048   6 0.94094 1.2464 0.269, 6.26 -0.3
RIX:CC(010 x 015) m 7.8317 7.3224   6 2.9894 0.935 1.09, 18.4 1.23
RIX:CC(010 x 060) m 2.7433 1.0076   3 0.58173 0.3673 1.84, 3.83 -0.07
RIX:CC(011 x 032) m 2.7367 0.27791   3 0.16045 0.1016 2.52, 3.05 -0.07
RIX:CC(012 x 038) m 0.12727 0.08573   3 0.04949 0.6736 0.0607, 0.224 -0.74
RIX:CC(013 x 041) m 2.8959 1.8763   9 0.62544 0.6479 0.241, 4.5 -0.03
RIX:CC(014 x 059) m 5.855 4.39   6 1.7922 0.7498 1.2, 10.1 0.72
RIX:CC(015 x 018) m 6.679 6.6881   6 2.7304 1.0014 0.684, 17.0 0.93
RIX:CC(015 x 059) m 0.28927 0.34059   3 0.19664 1.1774 0.0488, 0.679 -0.7
RIX:CC(016 x 038) m 1.2855 0.9941   6 0.40584 0.7733 0.138, 2.43 -0.44
RIX:CC(017 x 041) m 3.4017 1.6327   6 0.66654 0.48 2.03, 6.37 0.1
RIX:CC(018 x 009) m 1.5346 2.0259   3 1.1697 1.3201 0.0379, 3.84 -0.38
RIX:CC(019 x 002) m 3.9304 3.9849   9 1.3283 1.0139 0.595, 10.0 0.23
RIX:CC(019 x 004) m 3.272 2.5959   6 1.0598 0.7934 0.752, 6.51 0.07
RIX:CC(019 x 027) m 1.5033 0.26083   3 0.15059 0.1735 1.31, 1.8 -0.39
RIX:CC(021 x 023) m 1.5967 0.38889   3 0.22452 0.2436 1.18, 1.95 -0.36
RIX:CC(022 x 024) m 9.7267 5.3697   3 3.1002 0.5521 4.18, 14.9 1.71
RIX:CC(022 x 044) m 1.3477 0.68532   3 0.39567 0.5085 0.693, 2.06 -0.43
RIX:CC(023 x 025) m 15.923 12.568   6 5.131 0.7893 2.4, 29.7 3.29
RIX:CC(024 x 023) m 2.8767 0.86962   3 0.50207 0.3023 1.93, 3.64 -0.04
RIX:CC(024 x 052) m 0.10993 0.03148   3 0.01817 0.2863 0.088, 0.146 -0.74
RIX:CC(025 x 028) m 5.5383 2.7634   6 1.1282 0.499 3.66, 10.8 0.64
RIX:CC(026 x 034) m 2.4665 3.0581   6 1.2485 1.2399 0.228, 8.47 -0.14
RIX:CC(027 x 036) m 2.7267 0.11015   3 0.0636 0.0404 2.62, 2.84 -0.07
RIX:CC(027 x 045) m 1.3923 0.84083   3 0.48545 0.6039 0.437, 2.02 -0.41
RIX:CC(029 x 027) m 7.6933 4.98   6 2.0331 0.6473 1.45, 16.5 1.19
RIX:CC(029 x 071) m 1.0427 0.33074   3 0.19095 0.3172 0.803, 1.42 -0.5
RIX:CC(030 x 023) m 0.67567 0.27634   3 0.15955 0.409 0.359, 0.868 -0.6
RIX:CC(030 x 061) m 2.1358 1.1552   6 0.47162 0.5409 0.665, 3.7 -0.22
RIX:CC(032 x 013) m 0.77333 0.12393   3 0.07155 0.1603 0.64, 0.885 -0.57
RIX:CC(033 x 046) m 1.1443 1.8514   6 0.75583 1.6179 -0.48
RIX:CC(035 x 020) m 0.47833 0.06816   3 0.03935 0.1425 0.437, 0.557 -0.65
RIX:CC(035 x 071) m 3.72 0.49112   3 0.28355 0.132 3.3, 4.26 0.18
RIX:CC(036 x 051) m 1.93 0.41581   3 0.24007 0.2154 1.5, 2.33 -0.28
RIX:CC(037 x 046) m 0.21833 0.03153   3 0.01821 0.1444 0.186, 0.249 -0.71
RIX:CC(037 x 057) m 2.6632 1.6602   6 0.67779 0.6234 0.889, 5.33 -0.09
RIX:CC(038 x 013) m 0.5763 0.42121   6 0.17196 0.7309 0.0838, 1.02 -0.62
RIX:CC(039 x 020) m 1.06 0.37242   3 0.21502 0.3513 0.64, 1.35 -0.5
RIX:CC(040 x 003) m 2.005 1.0748   6 0.43879 0.5361 1.0, 3.57 -0.26
RIX:CC(040 x 015) m 1.4667 0.12014   3 0.06936 0.0819 1.35, 1.59 -0.39
RIX:CC(041 x 016) m 2.0012 0.75625   6 0.30874 0.3779 0.947, 2.87 -0.26
RIX:CC(042 x 017) m 1.9367 0.26951   3 0.1556 0.1392 1.7, 2.23 -0.28
RIX:CC(042 x 019) m 12.167 0.90185   3 0.52068 0.0741 11.3, 13.1 2.33
RIX:CC(043 x 033) m 1.0127 0.44187   3 0.25511 0.4363 0.712, 1.52 -0.51
RIX:CC(043 x 037) m 0.45717 0.15874   6 0.06481 0.3472 0.264, 0.645 -0.65
RIX:CC(044 x 060) m 0.58367 0.14069   3 0.08122 0.241 0.439, 0.72 -0.62
RIX:CC(045 x 044) m 4.3167 3.3616   6 1.3723 0.7787 1.06, 8.42 0.33
RIX:CC(046 x 068) m 1.3088 0.50792   6 0.20736 0.3881 0.713, 2.14 -0.44
RIX:CC(049 x 036) m 0.247 0.02805   3 0.0162 0.1136 0.22, 0.276 -0.71
RIX:CC(051 x 009) m 17.593 16.782   6 6.8512 0.9539 1.68, 35.1 3.72
RIX:CC(052 x 007) m 1.0053 0.07711   3 0.04452 0.0767 0.926, 1.08 -0.51
RIX:CC(052 x 014) m 2.267 2.8678   5 1.2825 1.265 0.176, 6.23 -0.19
RIX:CC(055 x 006) m 0.74067 0.15558   3 0.08982 0.2101 0.588, 0.899 -0.58
RIX:CC(055 x 028) m 25.467 5.1859   3 2.9941 0.2036 21.8, 31.4 5.72
RIX:CC(056 x 033) m 0.973 0.30674   3 0.17709 0.3152 0.619, 1.16 -0.52
RIX:CC(057 x 052) m 9.165 8.7817   6 3.5851 0.9582 1.13, 20.3 1.57
RIX:CC(058 x 022) m 0.63167 0.26766   3 0.15453 0.4237 0.332, 0.847 -0.61
RIX:CC(059 x 065) m 5.3072 4.4453   6 1.8148 0.8376 0.749, 9.8 0.58
RIX:CC(060 x 006) m 1.4802 0.68435   6 0.27939 0.4623 0.356, 2.15 -0.39
RIX:CC(060 x 037) m 2.9 1.2443   3 0.71842 0.4291 1.72, 4.2 -0.03
RIX:CC(061 x 025) m 1.1317 0.25982   3 0.15001 0.2296 0.955, 1.43 -0.48
RIX:CC(061 x 026) m 4.735 2.0091   6 0.82023 0.4243 2.99, 7.76 0.44
RIX:CC(061 x 039) m 1.818 1.6283   6 0.66476 0.8957 0.122, 3.73 -0.31
RIX:CC(062 x 046) m 0.96567 0.27198   3 0.15703 0.2817 0.708, 1.25 -0.52
RIX:CC(062 x 072) m 2.2533 1.2054   3 0.69595 0.5349 1.03, 3.44 -0.19
RIX:CC(063 x 001) m 0.64933 0.47708   3 0.27544 0.7347 0.2, 1.15 -0.6
RIX:CC(063 x 002) m 1.6333 0.3402   3 0.19641 0.2083 1.3, 1.98 -0.35
RIX:CC(065 x 010) m 3.9 3.3546   6 1.3695 0.8601 0.23
RIX:CC(065 x 072) m 3.8567 0.64376   3 0.37168 0.1669 3.48, 4.6 0.21
RIX:CC(068 x 035) m 5.4567 3.4951   3 2.0179 0.6405 1.95, 8.94 0.62
RIX:CC(068 x 043) m 2.2567 1.8831   3 1.0872 0.8345 1.11, 4.43 -0.19
RIX:CC(070 x 003) m 0.877 0.14992   3 0.08656 0.171 0.785, 1.05 -0.55
RIX:CC(072 x 063) m 4.4167 1.7672   3 1.0203 0.4001 2.98, 6.39 0.36
RIX:CC(072 x 075) m 0.50233 0.4931   3 0.28469 0.9816 0.124, 1.06 -0.64
RIX:CC(074 x 058) m 0.847 0.40809   3 0.23561 0.4818 0.434, 1.25 -0.55
RIX:CC(074 x 062) m 1.8633 0.43247   3 0.24969 0.2321 1.46, 2.32 -0.29
RIX:CC(075 x 021) m 2.18 0.43   3 0.24826 0.1972 1.75, 2.61 -0.21
RIX:CC(075 x 035) m 0.455 0.25472   3 0.14706 0.5598 0.237, 0.735 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(001 x 055) m 0.4161666667 1.5631734189 3.4925087242 -2.6601753908
RIX:CC(002 x 011) m 1.1378 1.7123706857 4.507763879 -2.232163879
RIX:CC(002 x 021) m 1.4286666667 2.2106610494 5.7792713269 -2.9219379935
RIX:CC(003 x 051) m 0.5846666667 1.5631734189 3.6610087242 -2.4916753908
RIX:CC(003 x 062) m 4.4183333333 1.5631734189 7.4946753908 1.3419912758
RIX:CC(005 x 001) m 0.7953333333 2.2106610494 5.1459379935 -3.5552713269
RIX:CC(005 x 038) m 1.88 2.2106610494 6.2306046602 -2.4706046602
RIX:CC(005 x 040) m 3.207 1.5631734189 6.2833420575 0.1306579425
RIX:CC(006 x 007) m 2.4111666667 1.5631734189 5.4875087242 -0.6651753908
RIX:CC(006 x 039) m 0.823 2.2106610494 5.1736046602 -3.5276046602
RIX:CC(007 x 070) m 0.7096666667 2.2106610494 5.0602713269 -3.6409379935
RIX:CC(008 x 009) m 1.7176666667 2.2106610494 6.0682713269 -2.6329379935
RIX:CC(008 x 010) m 8.5133333333 2.2106610494 12.8639379935 4.1627286731
RIX:CC(008 x 018) m 0.7773333333 2.2106610494 5.1279379935 -3.5732713269
RIX:CC(009 x 040) m 1.8491666667 1.5631734189 4.9255087242 -1.2271753908
RIX:CC(010 x 015) m 7.8316666667 1.5631734189 10.9080087242 4.7553246092
RIX:CC(010 x 060) m 2.7433333333 2.2106610494 7.0939379935 -1.6072713269
RIX:CC(011 x 032) m 2.7366666667 2.2106610494 7.0872713269 -1.6139379935
RIX:CC(012 x 038) m 0.1272666667 2.2106610494 4.4778713269 -4.2233379935
RIX:CC(013 x 041) m 2.8958888889 1.276325752 5.4077116606 0.3840661172
RIX:CC(014 x 059) m 5.855 1.5631734189 8.9313420575 2.7786579425
RIX:CC(015 x 018) m 6.679 1.5631734189 9.7553420575 3.6026579425
RIX:CC(015 x 059) m 0.2892666667 2.2106610494 4.6398713269 -4.0613379935
RIX:CC(016 x 038) m 1.2855 1.5631734189 4.3618420575 -1.7908420575
RIX:CC(017 x 041) m 3.4016666667 1.5631734189 6.4780087242 0.3253246092
RIX:CC(018 x 009) m 1.5346333333 2.2106610494 5.8852379935 -2.8159713269
RIX:CC(019 x 002) m 3.9304444444 1.276325752 6.4422672161 1.4186216727
RIX:CC(019 x 004) m 3.272 1.5631734189 6.3483420575 0.1956579425
RIX:CC(019 x 027) m 1.5033333333 2.2106610494 5.8539379935 -2.8472713269
RIX:CC(021 x 023) m 1.5966666667 2.2106610494 5.9472713269 -2.7539379935
RIX:CC(022 x 024) m 9.7266666667 2.2106610494 14.0772713269 5.3760620065
RIX:CC(022 x 044) m 1.3476666667 2.2106610494 5.6982713269 -3.0029379935
RIX:CC(023 x 025) m 15.9233333333 1.5631734189 18.9996753908 12.8469912758
RIX:CC(024 x 023) m 2.8766666667 2.2106610494 7.2272713269 -1.4739379935
RIX:CC(024 x 052) m 0.1099333333 2.2106610494 4.4605379935 -4.2406713269
RIX:CC(025 x 028) m 5.5383333333 1.5631734189 8.6146753908 2.4619912758
RIX:CC(026 x 034) m 2.4665 1.5631734189 5.5428420575 -0.6098420575
RIX:CC(027 x 036) m 2.7266666667 2.2106610494 7.0772713269 -1.6239379935
RIX:CC(027 x 045) m 1.3923333333 2.2106610494 5.7429379935 -2.9582713269
RIX:CC(029 x 027) m 7.6933333333 1.5631734189 10.7696753908 4.6169912758
RIX:CC(029 x 071) m 1.0426666667 2.2106610494 5.3932713269 -3.3079379935
RIX:CC(030 x 023) m 0.6756666667 2.2106610494 5.0262713269 -3.6749379935
RIX:CC(030 x 061) m 2.1358333333 1.5631734189 5.2121753908 -0.9405087242
RIX:CC(032 x 013) m 0.7733333333 2.2106610494 5.1239379935 -3.5772713269
RIX:CC(033 x 046) m 1.1443333333 1.5631734189 4.2206753908 -1.9320087242
RIX:CC(035 x 020) m 0.4783333333 2.2106610494 4.8289379935 -3.8722713269
RIX:CC(035 x 071) m 3.72 2.2106610494 8.0706046602 -0.6306046602
RIX:CC(036 x 051) m 1.93 2.2106610494 6.2806046602 -2.4206046602
RIX:CC(037 x 046) m 0.2183333333 2.2106610494 4.5689379935 -4.1322713269
RIX:CC(037 x 057) m 2.6631666667 1.5631734189 5.7395087242 -0.4131753908
RIX:CC(038 x 013) m 0.5763 1.5631734189 3.6526420575 -2.5000420575
RIX:CC(039 x 020) m 1.06 2.2106610494 5.4106046602 -3.2906046602
RIX:CC(040 x 003) m 2.005 1.5631734189 5.0813420575 -1.0713420575
RIX:CC(040 x 015) m 1.4666666667 2.2106610494 5.8172713269 -2.8839379935
RIX:CC(041 x 016) m 2.0011666667 1.5631734189 5.0775087242 -1.0751753908
RIX:CC(042 x 017) m 1.9366666667 2.2106610494 6.2872713269 -2.4139379935
RIX:CC(042 x 019) m 12.1666666667 2.2106610494 16.5172713269 7.8160620065
RIX:CC(043 x 033) m 1.0126666667 2.2106610494 5.3632713269 -3.3379379935
RIX:CC(043 x 037) m 0.4571666667 1.5631734189 3.5335087242 -2.6191753908
RIX:CC(044 x 060) m 0.5836666667 2.2106610494 4.9342713269 -3.7669379935
RIX:CC(045 x 044) m 4.3166666667 1.5631734189 7.3930087242 1.2403246092
RIX:CC(046 x 068) m 1.3088333333 1.5631734189 4.3851753908 -1.7675087242
RIX:CC(049 x 036) m 0.247 2.2106610494 4.5976046602 -4.1036046602
RIX:CC(051 x 009) m 17.5933333333 1.5631734189 20.6696753908 14.5169912758
RIX:CC(052 x 007) m 1.0053333333 2.2106610494 5.3559379935 -3.3452713269
RIX:CC(052 x 014) m 2.267 1.7123706857 5.636963879 -1.102963879
RIX:CC(055 x 006) m 0.7406666667 2.2106610494 5.0912713269 -3.6099379935
RIX:CC(055 x 028) m 25.4666666667 2.2106610494 29.8172713269 21.1160620065
RIX:CC(056 x 033) m 0.973 2.2106610494 5.3236046602 -3.3776046602
RIX:CC(057 x 052) m 9.165 1.5631734189 12.2413420575 6.0886579425
RIX:CC(058 x 022) m 0.6316666667 2.2106610494 4.9822713269 -3.7189379935
RIX:CC(059 x 065) m 5.3071666667 1.5631734189 8.3835087242 2.2308246092
RIX:CC(060 x 006) m 1.4801666667 1.5631734189 4.5565087242 -1.5961753908
RIX:CC(060 x 037) m 2.9 2.2106610494 7.2506046602 -1.4506046602
RIX:CC(061 x 025) m 1.1316666667 2.2106610494 5.4822713269 -3.2189379935
RIX:CC(061 x 026) m 4.735 1.5631734189 7.8113420575 1.6586579425
RIX:CC(061 x 039) m 1.818 1.5631734189 4.8943420575 -1.2583420575
RIX:CC(062 x 046) m 0.9656666667 2.2106610494 5.3162713269 -3.3849379935
RIX:CC(062 x 072) m 2.2533333333 2.2106610494 6.6039379935 -2.0972713269
RIX:CC(063 x 001) m 0.6493333333 2.2106610494 4.9999379935 -3.7012713269
RIX:CC(063 x 002) m 1.6333333333 2.2106610494 5.9839379935 -2.7172713269
RIX:CC(065 x 010) m 3.9 1.5631734189 6.9763420575 0.8236579425
RIX:CC(065 x 072) m 3.8566666667 2.2106610494 8.2072713269 -0.4939379935
RIX:CC(068 x 035) m 5.4566666667 2.2106610494 9.8072713269 1.1060620065
RIX:CC(068 x 043) m 2.2566666667 2.2106610494 6.6072713269 -2.0939379935
RIX:CC(070 x 003) m 0.877 2.2106610494 5.2276046602 -3.4736046602
RIX:CC(072 x 063) m 4.4166666667 2.2106610494 8.7672713269 0.0660620065
RIX:CC(072 x 075) m 0.5023333333 2.2106610494 4.8529379935 -3.8482713269
RIX:CC(074 x 058) m 0.847 2.2106610494 5.1976046602 -3.5036046602
RIX:CC(074 x 062) m 1.8633333333 2.2106610494 6.2139379935 -2.4872713269
RIX:CC(075 x 021) m 2.18 2.2106610494 6.5306046602 -2.1706046602
RIX:CC(075 x 035) m 0.455 2.2106610494 4.8056046602 -3.8956046602




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA