Project measure / variable:   Graham3   ics_CD4_pos_IFNg_pos

ID, description, units MPD:113844   ics_CD4_pos_IFNg_pos   percentage of splenic CD4+ T cells that are IFNg+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28   [%]  
Data set, strains Graham3   CC RIX   102 strains     sex: m     age: 8-10wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Graham3 - percentage of splenic CD4+ T cells that are IFNg+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested102 strains
Mean of the strain means1.3341   %
Median of the strain means0.16173   %
SD of the strain means± 3.1677
Coefficient of variation (CV)2.3744
Min–max range of strain means0.0046   –   18.132   %
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 101 5459.9271 54.0587 2.7685 < 0.0001
Residuals 358 6990.4766 19.5265


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(001 x 055) m 0.04702 0.02812   6 0.01148 0.598 0.0192, 0.101 -0.41
RIX:CC(001 x 074) m 0.0343 0.0386   3 0.02229 1.1254 -0.41
RIX:CC(002 x 011) m 2.0632 2.142   5 0.95795 1.0382 0.23
RIX:CC(002 x 021) m 0.0382 0.05061   6 0.02066 1.325 -0.41
RIX:CC(003 x 051) m 3.7665 3.8143   6 1.5572 1.0127 0.136, 8.18 0.77
RIX:CC(003 x 062) m 0.45402 0.92974   6 0.37956 2.0478 0.0453, 2.35 -0.28
RIX:CC(004 x 011) m 1.3842 1.2985   6 0.53011 0.9381 0.508, 3.75 0.02
RIX:CC(004 x 012) m 1.894 2.4287   6 0.99152 1.2823 0.18
RIX:CC(005 x 001) m 0.37015 0.23958   6 0.09781 0.6473 0.0719, 0.76 -0.3
RIX:CC(005 x 038) m 0.0152 0.01408   3 0.00812978 0.9264 -0.42
RIX:CC(005 x 040) m 7.2946 12.311   6 5.026 1.6877 0.0176, 30.6 1.88
RIX:CC(006 x 007) m 0.32125 0.24658   6 0.10067 0.7676 0.0686, 0.639 -0.32
RIX:CC(006 x 039) m 0.16133 0.05033   3 0.02906 0.312 0.108, 0.208 -0.37
RIX:CC(007 x 070) m 0.1165 0.05176   3 0.02988 0.4443 0.0585, 0.158 -0.38
RIX:CC(008 x 009) m 0.488 0.10623   3 0.06133 0.2177 0.37, 0.576 -0.27
RIX:CC(008 x 010) m 0.14867 0.15941   3 0.09204 1.0723 -0.37
RIX:CC(008 x 018) m 0.03103 0.02797   3 0.01615 0.9013 -0.41
RIX:CC(009 x 040) m 0.67637 0.8682   6 0.35444 1.2836 -0.21
RIX:CC(010 x 015) m 0.03649 0.02787   6 0.01138 0.7637 0.00607, 0.0739 -0.41
RIX:CC(010 x 060) m 0.0717 0.03573   3 0.02063 0.4983 0.0323, 0.102 -0.4
RIX:CC(011 x 032) m 0.0592 0.01162   3 0.00670994 0.1963 0.051, 0.0725 -0.4
RIX:CC(011 x 042) m 0.20992 0.31414   6 0.12825 1.4965 0.0266, 0.843 -0.35
RIX:CC(012 x 032) m 0.00859333 0.01387   6 0.00566228 1.614 -0.42
RIX:CC(012 x 038) m 0.06437 0.01637   3 0.00945098 0.2543 0.0455, 0.0748 -0.4
RIX:CC(013 x 041) m 0.08833 0.0601   9 0.02003 0.6803 0.0159, 0.183 -0.39
RIX:CC(014 x 059) m 0.02908 0.01618   6 0.00660734 0.5565 0.0128, 0.0506 -0.41
RIX:CC(015 x 018) m 6.6033 6.1193   6 2.4982 0.9267 1.1, 16.3 1.66
RIX:CC(015 x 059) m 0.1123 0.06995   3 0.04039 0.6229 0.0611, 0.192 -0.39
RIX:CC(016 x 038) m 18.132 19.618   6 8.0089 1.0819 0.0801, 38.4 5.3
RIX:CC(017 x 004) m 0.05997 0.05005   6 0.02043 0.8347 0.0215, 0.157 -0.4
RIX:CC(017 x 041) m 0.08355 0.0533   6 0.02176 0.638 0.0356, 0.185 -0.39
RIX:CC(018 x 009) m 10.953 18.143   3 10.475 1.6564 0.177, 31.9 3.04
RIX:CC(018 x 065) m 0.06903 0.07218   3 0.04167 1.0456 -0.4
RIX:CC(019 x 002) m 0.22825 0.31217   11 0.09412 1.3676 0.0143, 0.907 -0.35
RIX:CC(019 x 004) m 0.40573 0.32394   6 0.13225 0.7984 0.0984, 0.796 -0.29
RIX:CC(019 x 027) m 0.11623 0.06315   3 0.03646 0.5433 0.0437, 0.159 -0.38
RIX:CC(021 x 023) m 0.45067 0.15483   3 0.08939 0.3436 0.302, 0.611 -0.28
RIX:CC(022 x 024) m 4.9 0.28618   3 0.16523 0.0584 4.72, 5.23 1.13
RIX:CC(022 x 044) m 0.0317 0.01337   3 0.00772032 0.4218 0.0192, 0.0458 -0.41
RIX:CC(023 x 025) m 7.7917 8.367   6 3.4158 1.0738 0.163, 18.1 2.04
RIX:CC(024 x 023) m 0.01471 0.01606   6 0.00655505 1.0919 -0.42
RIX:CC(024 x 052) m 0.0865 0.02077   3 0.01199 0.2402 0.0627, 0.101 -0.39
RIX:CC(025 x 028) m 0.364 0.22655   6 0.09249 0.6224 0.11, 0.703 -0.31
RIX:CC(026 x 034) m 1.4929 2.2169   6 0.90503 1.485 0.05
RIX:CC(027 x 036) m 0.0793 0.04379   3 0.02528 0.5522 0.0289, 0.108 -0.4
RIX:CC(027 x 045) m 0.44367 0.14755   3 0.08519 0.3326 0.31, 0.602 -0.28
RIX:CC(029 x 027) m 0.242 0.30461   6 0.12436 1.2587 -0.34
RIX:CC(029 x 071) m 0.10767 0.0023094   3 0.00133333 0.0214 0.105, 0.109 -0.39
RIX:CC(030 x 023) m 0.186 0.16139   3 0.09318 0.8677 -0.36
RIX:CC(030 x 061) m 1.1428 0.81678   6 0.33345 0.7147 0.236, 2.33 -0.06
RIX:CC(032 x 013) m 1.4733 1.1808   6 0.48205 0.8014 0.364, 2.84 0.04
RIX:CC(032 x 017) m 0.09643 0.06256   6 0.02554 0.6488 0.0236, 0.172 -0.39
RIX:CC(033 x 046) m 0.0046 0.00722689   6 0.00295037 1.5711 -0.42
RIX:CC(035 x 020) m 0.79267 0.37344   3 0.21561 0.4711 0.529, 1.22 -0.17
RIX:CC(035 x 071) m 0.05177 0.0080829   3 0.00466667 0.1561 0.0431, 0.0591 -0.4
RIX:CC(036 x 051) m 0.26933 0.02656   3 0.01533 0.0986 0.254, 0.3 -0.34
RIX:CC(037 x 046) m 0.08083 0.02631   3 0.01519 0.3255 0.0528, 0.105 -0.4
RIX:CC(037 x 057) m 0.16213 0.08972   6 0.03663 0.5534 0.0578, 0.328 -0.37
RIX:CC(038 x 013) m 17.765 19.678   6 8.0336 1.1077 0.0175, 41.2 5.19
RIX:CC(039 x 020) m 0.46867 0.13848   3 0.07995 0.2955 0.32, 0.594 -0.27
RIX:CC(040 x 003) m 1.9623 2.2281   6 0.90963 1.1355 0.0363, 5.14 0.2
RIX:CC(040 x 015) m 0.02852 0.01786   3 0.01031 0.626 0.00827, 0.042 -0.41
RIX:CC(041 x 012) m 0.94033 0.69596   6 0.28413 0.7401 0.229, 2.13 -0.12
RIX:CC(041 x 016) m 0.03474 0.01999   6 0.00815953 0.5752 0.00937, 0.059 -0.41
RIX:CC(042 x 017) m 0.01183 0.01025   3 0.00592012 0.8665 -0.42
RIX:CC(042 x 019) m 5.5348 6.0813   6 2.4827 1.0987 1.33
RIX:CC(043 x 033) m 0.2319 0.29194   3 0.16855 1.2589 0.062, 0.569 -0.35
RIX:CC(043 x 037) m 0.2115 0.08036   6 0.03281 0.38 0.12, 0.352 -0.35
RIX:CC(044 x 060) m 0.0157 0.01864   3 0.01076 1.1872 -0.42
RIX:CC(045 x 044) m 0.06233 0.07776   6 0.03175 1.2475 -0.4
RIX:CC(046 x 068) m 0.2975 0.14685   6 0.05995 0.4936 0.116, 0.515 -0.33
RIX:CC(049 x 036) m 0.11087 0.01917   3 0.01107 0.1729 0.0996, 0.133 -0.39
RIX:CC(051 x 005) m 0.10854 0.06167   7 0.02331 0.5682 0.0455, 0.224 -0.39
RIX:CC(051 x 009) m 3.0617 1.6609   6 0.67806 0.5425 1.06, 5.21 0.55
RIX:CC(052 x 007) m 0.52967 0.1282   3 0.07402 0.242 0.429, 0.674 -0.25
RIX:CC(052 x 014) m 0.03174 0.01058   5 0.00473187 0.3334 0.0221, 0.0491 -0.41
RIX:CC(055 x 006) m 0.01443 0.00125033   3 0.00072188 0.0866 0.0132, 0.0157 -0.42
RIX:CC(055 x 028) m 3.61 0.62746   3 0.36226 0.1738 3.18, 4.33 0.72
RIX:CC(056 x 033) m 0.0814 0.0298   3 0.01721 0.3661 0.0538, 0.113 -0.4
RIX:CC(057 x 052) m 0.02312 0.03291   6 0.01344 1.4237 -0.41
RIX:CC(058 x 022) m 0.03587 0.03118   3 0.018 0.8693 -0.41
RIX:CC(059 x 065) m 0.16568 0.0817   6 0.03335 0.4931 0.0511, 0.302 -0.37
RIX:CC(060 x 006) m 0.0293 0.02997   6 0.01224 1.0228 -0.41
RIX:CC(060 x 037) m 0.0114 0.00553634   3 0.00319641 0.4856 0.00731, 0.0177 -0.42
RIX:CC(061 x 025) m 0.09847 0.10356   3 0.05979 1.0517 0.0359, 0.218 -0.39
RIX:CC(061 x 026) m 0.34812 0.40438   6 0.16509 1.1616 0.024, 1.04 -0.31
RIX:CC(061 x 039) m 10.22 11.172   6 4.5611 1.0932 0.0184, 21.3 2.81
RIX:CC(062 x 046) m 0.0145 0.00115326   3 0.00066583 0.0795 0.0134, 0.0157 -0.42
RIX:CC(062 x 072) m 5.1553 7.1428   3 4.1239 1.3855 0.836, 13.4 1.21
RIX:CC(063 x 001) m 0.1772 0.09687   3 0.05593 0.5467 0.0666, 0.247 -0.37
RIX:CC(063 x 002) m 0.21833 0.02401   3 0.01386 0.11 0.191, 0.236 -0.35
RIX:CC(065 x 010) m 0.04133 0.06221   6 0.0254 1.505 -0.41
RIX:CC(065 x 072) m 1.1303 0.4391   3 0.25352 0.3885 0.641, 1.49 -0.06
RIX:CC(068 x 035) m 0.1017 0.12697   3 0.0733 1.2484 -0.39
RIX:CC(068 x 043) m 0.366 0.18789   3 0.10848 0.5133 0.202, 0.571 -0.31
RIX:CC(070 x 003) m 0.03021 0.02453   3 0.01416 0.812 0.00904, 0.0571 -0.41
RIX:CC(072 x 063) m 0.12933 0.22401   3 0.12933 1.7321 -0.38
RIX:CC(072 x 075) m 0.20187 0.11086   3 0.064 0.5492 0.0806, 0.298 -0.36
RIX:CC(074 x 058) m 5.0033 4.775   3 2.7568 0.9544 1.88, 10.5 1.16
RIX:CC(074 x 062) m 0.03348 0.02273   3 0.01312 0.679 0.00774, 0.0508 -0.41
RIX:CC(075 x 021) m 0.51067 0.11906   3 0.06874 0.2331 0.38, 0.613 -0.26
RIX:CC(075 x 035) m 0.01633 0.02829   3 0.01633 1.7321 -0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(001 x 055) m 0.0470166667 1.8039988384 3.5947833663 -3.500750033
RIX:CC(001 x 074) m 0.0343 2.5512396238 5.0515997828 -4.9829997828
RIX:CC(002 x 011) m 2.0632 1.9761817151 5.9495837004 -1.8231837004
RIX:CC(002 x 021) m 0.0382 1.8039988384 3.5859666997 -3.5095666997
RIX:CC(003 x 051) m 3.7665 1.8039988384 7.3142666997 0.2187333003
RIX:CC(003 x 062) m 0.4540166667 1.8039988384 4.0017833663 -3.093750033
RIX:CC(004 x 011) m 1.3841666667 1.8039988384 4.9319333663 -2.163600033
RIX:CC(004 x 012) m 1.8939833333 1.8039988384 5.441750033 -1.6537833663
RIX:CC(005 x 001) m 0.37015 1.8039988384 3.9179166997 -3.1776166997
RIX:CC(005 x 038) m 0.0152 2.5512396238 5.0324997828 -5.0020997828
RIX:CC(005 x 040) m 7.2945833333 1.8039988384 10.842350033 3.7468166337
RIX:CC(006 x 007) m 0.32125 1.8039988384 3.8690166997 -3.2265166997
RIX:CC(006 x 039) m 0.1613333333 2.5512396238 5.1786331161 -4.8559664495
RIX:CC(007 x 070) m 0.1165 2.5512396238 5.1337997828 -4.9007997828
RIX:CC(008 x 009) m 0.488 2.5512396238 5.5052997828 -4.5292997828
RIX:CC(008 x 010) m 0.1486666667 2.5512396238 5.1659664495 -4.8686331161
RIX:CC(008 x 018) m 0.0310333333 2.5512396238 5.0483331161 -4.9862664495
RIX:CC(009 x 040) m 0.6763666667 1.8039988384 4.2241333663 -2.871400033
RIX:CC(010 x 015) m 0.036495 1.8039988384 3.5842616997 -3.5112716997
RIX:CC(010 x 060) m 0.0717 2.5512396238 5.0889997828 -4.9455997828
RIX:CC(011 x 032) m 0.0592 2.5512396238 5.0764997828 -4.9580997828
RIX:CC(011 x 042) m 0.2099166667 1.8039988384 3.7576833663 -3.337850033
RIX:CC(012 x 032) m 0.0085933333 1.8039988384 3.556360033 -3.5391733663
RIX:CC(012 x 038) m 0.0643666667 2.5512396238 5.0816664495 -4.9529331161
RIX:CC(013 x 041) m 0.0883333333 1.4729588836 2.9850727135 -2.8084060469
RIX:CC(014 x 059) m 0.0290833333 1.8039988384 3.576850033 -3.5186833663
RIX:CC(015 x 018) m 6.6033333333 1.8039988384 10.151100033 3.0555666337
RIX:CC(015 x 059) m 0.1123 2.5512396238 5.1295997828 -4.9049997828
RIX:CC(016 x 038) m 18.13235 1.8039988384 21.6801166997 14.5845833003
RIX:CC(017 x 004) m 0.0599666667 1.8039988384 3.6077333663 -3.487800033
RIX:CC(017 x 041) m 0.08355 1.8039988384 3.6313166997 -3.4642166997
RIX:CC(018 x 009) m 10.9533333333 2.5512396238 15.9706331161 5.9360335505
RIX:CC(018 x 065) m 0.0690333333 2.5512396238 5.0863331161 -4.9482664495
RIX:CC(019 x 002) m 0.2282545455 1.3323414405 2.8484539017 -2.3919448108
RIX:CC(019 x 004) m 0.4057333333 1.8039988384 3.953500033 -3.1420333663
RIX:CC(019 x 027) m 0.1162333333 2.5512396238 5.1335331161 -4.9010664495
RIX:CC(021 x 023) m 0.4506666667 2.5512396238 5.4679664495 -4.5666331161
RIX:CC(022 x 024) m 4.9 2.5512396238 9.9172997828 -0.1172997828
RIX:CC(022 x 044) m 0.0317 2.5512396238 5.0489997828 -4.9855997828
RIX:CC(023 x 025) m 7.7916666667 1.8039988384 11.3394333663 4.243899967
RIX:CC(024 x 023) m 0.014705 1.8039988384 3.5624716997 -3.5330616997
RIX:CC(024 x 052) m 0.0865 2.5512396238 5.1037997828 -4.9307997828
RIX:CC(025 x 028) m 0.364 1.8039988384 3.9117666997 -3.1837666997
RIX:CC(026 x 034) m 1.49285 1.8039988384 5.0406166997 -2.0549166997
RIX:CC(027 x 036) m 0.0793 2.5512396238 5.0965997828 -4.9379997828
RIX:CC(027 x 045) m 0.4436666667 2.5512396238 5.4609664495 -4.5736331161
RIX:CC(029 x 027) m 0.242 1.8039988384 3.7897666997 -3.3057666997
RIX:CC(029 x 071) m 0.1076666667 2.5512396238 5.1249664495 -4.9096331161
RIX:CC(030 x 023) m 0.186 2.5512396238 5.2032997828 -4.8312997828
RIX:CC(030 x 061) m 1.1428333333 1.8039988384 4.690600033 -2.4049333663
RIX:CC(032 x 013) m 1.4733333333 1.8039988384 5.021100033 -2.0744333663
RIX:CC(032 x 017) m 0.0964333333 1.8039988384 3.644200033 -3.4513333663
RIX:CC(033 x 046) m 0.0046 1.8039988384 3.5523666997 -3.5431666997
RIX:CC(035 x 020) m 0.7926666667 2.5512396238 5.8099664495 -4.2246331161
RIX:CC(035 x 071) m 0.0517666667 2.5512396238 5.0690664495 -4.9655331161
RIX:CC(036 x 051) m 0.2693333333 2.5512396238 5.2866331161 -4.7479664495
RIX:CC(037 x 046) m 0.0808333333 2.5512396238 5.0981331161 -4.9364664495
RIX:CC(037 x 057) m 0.1621333333 1.8039988384 3.709900033 -3.3856333663
RIX:CC(038 x 013) m 17.7650166667 1.8039988384 21.3127833663 14.217249967
RIX:CC(039 x 020) m 0.4686666667 2.5512396238 5.4859664495 -4.5486331161
RIX:CC(040 x 003) m 1.9623166667 1.8039988384 5.5100833663 -1.585450033
RIX:CC(040 x 015) m 0.0285233333 2.5512396238 5.0458231161 -4.9887764495
RIX:CC(041 x 012) m 0.9403333333 1.8039988384 4.488100033 -2.6074333663
RIX:CC(041 x 016) m 0.034745 1.8039988384 3.5825116997 -3.5130216997
RIX:CC(042 x 017) m 0.0118333333 2.5512396238 5.0291331161 -5.0054664495
RIX:CC(042 x 019) m 5.5348416667 1.8039988384 9.0826083663 1.987074967
RIX:CC(043 x 033) m 0.2319 2.5512396238 5.2491997828 -4.7853997828
RIX:CC(043 x 037) m 0.2115 1.8039988384 3.7592666997 -3.3362666997
RIX:CC(044 x 060) m 0.0157 2.5512396238 5.0329997828 -5.0015997828
RIX:CC(045 x 044) m 0.0623333333 1.8039988384 3.610100033 -3.4854333663
RIX:CC(046 x 068) m 0.2975 1.8039988384 3.8452666997 -3.2502666997
RIX:CC(049 x 036) m 0.1108666667 2.5512396238 5.1281664495 -4.9064331161
RIX:CC(051 x 005) m 0.1085428571 1.6701783846 3.393136577 -3.1760508627
RIX:CC(051 x 009) m 3.0616666667 1.8039988384 6.6094333663 -0.486100033
RIX:CC(052 x 007) m 0.5296666667 2.5512396238 5.5469664495 -4.4876331161
RIX:CC(052 x 014) m 0.03174 1.9761817151 3.9181237004 -3.8546437004
RIX:CC(055 x 006) m 0.0144333333 2.5512396238 5.0317331161 -5.0028664495
RIX:CC(055 x 028) m 3.61 2.5512396238 8.6272997828 -1.4072997828
RIX:CC(056 x 033) m 0.0814 2.5512396238 5.0986997828 -4.9358997828
RIX:CC(057 x 052) m 0.0231166667 1.8039988384 3.5708833663 -3.524650033
RIX:CC(058 x 022) m 0.0358666667 2.5512396238 5.0531664495 -4.9814331161
RIX:CC(059 x 065) m 0.1656833333 1.8039988384 3.713450033 -3.3820833663
RIX:CC(060 x 006) m 0.0293016667 1.8039988384 3.5770683663 -3.518465033
RIX:CC(060 x 037) m 0.0114 2.5512396238 5.0286997828 -5.0058997828
RIX:CC(061 x 025) m 0.0984666667 2.5512396238 5.1157664495 -4.9188331161
RIX:CC(061 x 026) m 0.3481166667 1.8039988384 3.8958833663 -3.199650033
RIX:CC(061 x 039) m 10.22015 1.8039988384 13.7679166997 6.6723833003
RIX:CC(062 x 046) m 0.0145 2.5512396238 5.0317997828 -5.0027997828
RIX:CC(062 x 072) m 5.1553333333 2.5512396238 10.1726331161 0.1380335505
RIX:CC(063 x 001) m 0.1772 2.5512396238 5.1944997828 -4.8400997828
RIX:CC(063 x 002) m 0.2183333333 2.5512396238 5.2356331161 -4.7989664495
RIX:CC(065 x 010) m 0.0413333333 1.8039988384 3.589100033 -3.5064333663
RIX:CC(065 x 072) m 1.1303333333 2.5512396238 6.1476331161 -3.8869664495
RIX:CC(068 x 035) m 0.1017 2.5512396238 5.1189997828 -4.9155997828
RIX:CC(068 x 043) m 0.366 2.5512396238 5.3832997828 -4.6512997828
RIX:CC(070 x 003) m 0.0302133333 2.5512396238 5.0475131161 -4.9870864495
RIX:CC(072 x 063) m 0.1293333333 2.5512396238 5.1466331161 -4.8879664495
RIX:CC(072 x 075) m 0.2018666667 2.5512396238 5.2191664495 -4.8154331161
RIX:CC(074 x 058) m 5.0033333333 2.5512396238 10.0206331161 -0.0139664495
RIX:CC(074 x 062) m 0.03348 2.5512396238 5.0507797828 -4.9838197828
RIX:CC(075 x 021) m 0.5106666667 2.5512396238 5.5279664495 -4.5066331161
RIX:CC(075 x 035) m 0.0163333333 2.5512396238 5.0336331161 -5.0009664495




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA