Project measure / variable:   CSNA03   omit_in_acq_Binghamton

ID, description, units MPD:112877   omit_in_acq_Binghamton   total number of omissions (successful response in central nose poke hole, but no response in flanking hole within 30 s) (reversal learning assay), founders   [n]  acquisition  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - total number of omissions (successful response in central nose poke hole, but no response in flanking hole within 30 s) (reversal learning assay), founders acquisition



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means47.337   n 41.267   n
Median of the strain means44.145   n 19.0   n
SD of the strain means± 29.593 ± 39.571
Coefficient of variation (CV)0.6251 0.9589
Min–max range of strain means11.4   –   94.67   n 4.5   –   91.75   n
Mean sample size per strain6.0   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 828.5762 828.5762 0.4402 0.5092
strain 7 76889.5602 10984.2229 5.8358 < 0.0001
sex:strain 7 9550.3457 1364.3351 0.7249 0.6513
Residuals 69 129871.8238 1882.2003


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 55.57 34.923   7 13.2 0.6284 8.0, 111.0 0.28
129S1/SvImJ m 84.8 81.78   5 36.574 0.9644 11.0, 192.0 1.1
A/J f 94.67 72.66   6 29.662 0.7675 9.0, 217.0 1.6
A/J m 89.0 65.07   6 26.563 0.7311 15.0, 181.0 1.21
C57BL/6J f 33.0 29.086   6 11.874 0.8814 2.0, 77.0 -0.48
C57BL/6J m 16.833 19.052   6 7.7778 1.1318 1.0, 50.0 -0.62
CAST/EiJ f 80.57 43.745   7 16.534 0.5429 7.0, 125.0 1.12
CAST/EiJ m 91.75 48.617   4 24.308 0.5299 47.0, 159.0 1.28
NOD/ShiLtJ f 15.2 19.499   5 8.7201 1.2828 3.0, 49.0 -1.09
NOD/ShiLtJ m 18.25 17.095   4 8.5477 0.9367 2.0, 34.0 -0.58
NZO/HlLtJ f 53.29 51.8   7 19.58 0.9722 6.0, 156.0 0.2
NZO/HlLtJ m 5.25 4.3493   4 2.1747 0.8284 1.0, 11.0 -0.91
PWK/PhJ f 11.4 6.9857   5 3.1241 0.6128 2.0, 20.0 -1.21
PWK/PhJ m 4.5 5.1962   4 2.5981 1.1547 1.0, 12.0 -0.93
WSB/EiJ f 35.0 29.487   5 13.187 0.8425 9.0, 81.0 -0.42
WSB/EiJ m 19.75 20.903   4 10.451 1.0584 1.0, 47.0 -0.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 55.5714285714 16.3977365383 88.2840178967 22.8588392461
129S1/SvImJ m 84.8 19.4020635246 123.506057672 46.093942328
A/J f 94.6666666667 17.7115797576 130.0003014985 59.3330318349
A/J m 89.0 17.7115797576 124.3336348318 53.6663651682
C57BL/6J f 33.0 17.7115797576 68.3336348318 -2.3336348318
C57BL/6J m 16.8333333333 17.7115797576 52.1669681651 -18.5003014985
CAST/EiJ f 80.5714285714 16.3977365383 113.2840178967 47.8588392461
CAST/EiJ m 91.75 21.6921664724 135.0246880479 48.4753119521
NOD/ShiLtJ f 15.2 19.4020635246 53.906057672 -23.506057672
NOD/ShiLtJ m 18.25 21.6921664724 61.5246880479 -25.0246880479
NZO/HlLtJ f 53.2857142857 16.3977365383 85.998303611 20.5731249604
NZO/HlLtJ m 5.25 21.6921664724 48.5246880479 -38.0246880479
PWK/PhJ f 11.4 19.4020635246 50.106057672 -27.306057672
PWK/PhJ m 4.5 21.6921664724 47.7746880479 -38.7746880479
WSB/EiJ f 35.0 19.4020635246 73.706057672 -3.706057672
WSB/EiJ m 19.75 21.6921664724 63.0246880479 -23.5246880479


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 70.1857142857 12.7016321057 95.5247770194 44.8466515521
A/J both 91.8333333333 12.5239781521 116.8179861269 66.8486805398
C57BL/6J both 24.9166666667 12.5239781521 49.9013194602 -0.0679861269
CAST/EiJ both 86.1607142857 13.5962848772 113.284560464 59.0368681075
NOD/ShiLtJ both 16.725 14.5515476435 45.754543254 -12.304543254
NZO/HlLtJ both 29.2678571429 13.5962848772 56.3917033211 2.1440109646
PWK/PhJ both 7.95 14.5515476435 36.979543254 -21.079543254
WSB/EiJ both 27.375 14.5515476435 56.404543254 -1.654543254




  GWAS USING LINEAR MIXED MODELS