Project measure / variable:   Schoonjans1   wMCA_liver_HFD

ID, description, units MPD:112854   wMCA_liver_HFD   bile acid ω-muricholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid ω-muricholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.06843   ng/mL
Median of the strain means0.04303   ng/mL
SD of the strain means± 0.06389
Coefficient of variation (CV)0.9336
Min–max range of strain means0.00949525   –   0.26242   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.6248 0.0179 2.4342 0.0001
Residuals 141 1.0341 0.0073


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.08212 0.07193   5 0.03217 0.8759 0.02498, 0.20562 0.21
BXD100 m 0.01411 0.00838203   7 0.00316811 0.5941 0.00375, 0.0297 -0.85
BXD11 m 0.12429 0.18874   3 0.10897 1.5185 0.00987769, 0.34213 0.87
BXD12 m 0.17891 0.25112   4 0.12556 1.4036 0.02067, 0.55205 1.73
BXD27 m 0.02314 0.01952   5 0.00873048 0.8435 0.01179, 0.05795 -0.71
BXD32 m 0.23339 0.20969   4 0.10485 0.8985 0.08584, 0.53619 2.58
BXD34 m 0.14038 0.03644   4 0.01822 0.2596 0.08611, 0.1646 1.13
BXD39 m 0.05748 0.0481   5 0.02151 0.8368 0.01745, 0.1388 -0.17
BXD40 m 0.02928 0.01535   5 0.00686517 0.5242 0.0158, 0.05377 -0.61
BXD43 m 0.05839 0.02656   5 0.01188 0.455 0.03235, 0.09544 -0.16
BXD45 m 0.12823 0.03922   5 0.01754 0.3058 0.09318, 0.1893 0.94
BXD48 m 0.02267 0.01384   5 0.00619106 0.6108 0.00527891, 0.04036 -0.72
BXD48a m 0.02166 0.02244   5 0.01004 1.0361 0.00904762, 0.06136 -0.73
BXD49 m 0.08564 0.08854   5 0.0396 1.0339 0.00716258, 0.22593 0.27
BXD51 m 0.01203 0.00434556   5 0.00194339 0.3611 0.00503465, 0.01567 -0.88
BXD53 m 0.01443 0.00690241   5 0.00308685 0.4785 0.00292208, 0.02152 -0.85
BXD55 m 0.02911 0.0265   5 0.01185 0.9105 0.00608519, 0.07035 -0.62
BXD6 m 0.12086 0.06783   5 0.03033 0.5612 0.04718, 0.2169 0.82
BXD62 m 0.00949525 0.00818286   5 0.00365949 0.8618 0.00390329, 0.02387 -0.92
BXD63 m 0.01866 0.00808477   5 0.00361562 0.4332 0.00544103, 0.02697 -0.78
BXD64 m 0.09291 0.03717   5 0.01662 0.4 0.03494, 0.13214 0.38
BXD66 m 0.05511 0.04343   9 0.01448 0.788 0.00672261, 0.14345 -0.21
BXD67 m 0.07537 0.03461   5 0.01548 0.4592 0.03754, 0.12185 0.11
BXD69 m 0.02325 0.02566   5 0.01147 1.1037 0.00286853, 0.0675 -0.71
BXD73 m 0.03564 0.02205   5 0.00985938 0.6186 0.00934891, 0.06938 -0.51
BXD75 m 0.05702 0.0391   4 0.01955 0.6857 0.01743, 0.09535 -0.18
BXD77 m 0.04474 0.03963   5 0.01773 0.8859 0.01271, 0.11166 -0.37
BXD79 m 0.04132 0.03274   5 0.01464 0.7923 0.0124, 0.09354 -0.42
BXD8 m 0.26242 0.34445   4 0.17222 1.3126 0.02604, 0.77428 3.04
BXD81 m 0.01337 0.01016   5 0.00454163 0.7594 0.00383616, 0.03054 -0.86
BXD84 m 0.03258 0.02251   5 0.01007 0.6909 0.01041, 0.05701 -0.56
BXD87 m 0.1052 0.06759   5 0.03023 0.6425 0.03187, 0.21656 0.58
BXD89 m 0.15811 0.17035   5 0.07618 1.0774 0.05518, 0.461 1.4
BXD90 m 0.01963 0.02051   3 0.01184 1.0449 0.00435672, 0.04294 -0.76
C57BL/6J m 0.03131 0.00950617   5 0.00425129 0.3036 0.02195, 0.04497 -0.58
DBA/2J m 0.0114 0.01361   5 0.00608695 1.1944 0.00098704, 0.03509 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.082122 0.0382985605 0.1578356303 0.0064083697
BXD100 m 0.0141080429 0.0323681914 0.0780977397 -0.0498816539
BXD11 m 0.12428923 0.0494432291 0.2220351064 0.0265433536
BXD12 m 0.178915 0.0428190924 0.2635654121 0.0942645879
BXD27 m 0.023144 0.0382985605 0.0988576303 -0.0525696303
BXD32 m 0.2333875 0.0428190924 0.3180379121 0.1487370879
BXD34 m 0.1403775 0.0428190924 0.2250279121 0.0557270879
BXD39 m 0.057482 0.0382985605 0.1331956303 -0.0182316303
BXD40 m 0.029284 0.0382985605 0.1049976303 -0.0464296303
BXD43 m 0.058386 0.0382985605 0.1340996303 -0.0173276303
BXD45 m 0.128228 0.0382985605 0.2039416303 0.0525143697
BXD48 m 0.022665782 0.0382985605 0.0983794123 -0.0530478483
BXD48a m 0.021659682 0.0382985605 0.0973733123 -0.0540539483
BXD49 m 0.085636516 0.0382985605 0.1613501463 0.0099228857
BXD51 m 0.01203493 0.0382985605 0.0877485603 -0.0636787003
BXD53 m 0.014426416 0.0382985605 0.0901400463 -0.0612872143
BXD55 m 0.02910821 0.0382985605 0.1048218403 -0.0466054203
BXD6 m 0.120862 0.0382985605 0.1965756303 0.0451483697
BXD62 m 0.009495252 0.0382985605 0.0852088823 -0.0662183783
BXD63 m 0.018664206 0.0382985605 0.0943778363 -0.0570494243
BXD64 m 0.092914 0.0382985605 0.1686276303 0.0172003697
BXD66 m 0.0551114011 0.0285460616 0.1115450092 -0.001322207
BXD67 m 0.075366 0.0382985605 0.1510796303 -0.0003476303
BXD69 m 0.023245706 0.0382985605 0.0989593363 -0.0524679243
BXD73 m 0.035639782 0.0382985605 0.1113534123 -0.0400738483
BXD75 m 0.0570175 0.0428190924 0.1416679121 -0.0276329121
BXD77 m 0.04474 0.0382985605 0.1204536303 -0.0309736303
BXD79 m 0.041324 0.0382985605 0.1170376303 -0.0343896303
BXD8 m 0.2624225 0.0428190924 0.3470729121 0.1777720879
BXD81 m 0.013372496 0.0382985605 0.0890861263 -0.0623411343
BXD84 m 0.032582 0.0382985605 0.1082956303 -0.0431316303
BXD87 m 0.105202 0.0382985605 0.1809156303 0.0294883697
BXD89 m 0.158114 0.0382985605 0.2338276303 0.0824003697
BXD90 m 0.0196289067 0.0494432291 0.1173747831 -0.0781169698
C57BL/6J m 0.03131 0.0382985605 0.1070236303 -0.0444036303
DBA/2J m 0.01139516 0.0382985605 0.0871087903 -0.0643184703




  GWAS USING LINEAR MIXED MODELS