Project measure / variable:   Schoonjans1   wMCA_liver_CD

ID, description, units MPD:112853   wMCA_liver_CD   bile acid ω-muricholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid ω-muricholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.04087   ng/mL
Median of the strain means0.02638   ng/mL
SD of the strain means± 0.05969
Coefficient of variation (CV)1.4605
Min–max range of strain means0.00326338   –   0.34586   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.4186 0.012 1.8806 0.0056
Residuals 134 0.8521 0.0064


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.01992 0.00824753   4 0.00412377 0.4141 0.01281, 0.03171 -0.35
BXD100 m 0.00521693 0.00293685   6 0.00119896 0.5629 0.0019031, 0.00982863 -0.6
BXD11 m 0.01587 0.01013   4 0.00506372 0.6382 0.00683602, 0.03036 -0.42
BXD12 m 0.15854 0.20135   4 0.10067 1.27 0.03401, 0.45668 1.97
BXD27 m 0.03848 0.04809   4 0.02405 1.2498 0.01253, 0.11058 -0.04
BXD32 m 0.04048 0.03371   5 0.01507 0.8327 0.00636409, 0.09542 -0.01
BXD34 m 0.03198 0.01382   5 0.00618254 0.4322 0.0231, 0.05626 -0.15
BXD39 m 0.0223 0.00772787   5 0.00345601 0.3465 0.01225, 0.02824 -0.31
BXD40 m 0.04246 0.03518   5 0.01573 0.8286 0.01106, 0.09972 0.03
BXD43 m 0.34586 0.56844   3 0.32819 1.6436 0.01161, 1.0022 5.11
BXD45 m 0.01996 0.0107   4 0.00534877 0.5359 0.00732487, 0.02894 -0.35
BXD48 m 0.02686 0.02899   5 0.01296 1.079 0.01047, 0.07818 -0.23
BXD48a m 0.01338 0.00691454   4 0.00345727 0.5168 0.00497988, 0.02191 -0.46
BXD49 m 0.00326338 0.00206798   4 0.00103399 0.6337 0.00104514, 0.00503003 -0.63
BXD51 m 0.01375 0.00718905   5 0.00321504 0.523 0.00761858, 0.02546 -0.45
BXD53 m 0.04593 0.03452   5 0.01544 0.7516 0.02133, 0.1061 0.08
BXD55 m 0.01166 0.00486836   5 0.00217719 0.4174 0.00378728, 0.0152 -0.49
BXD6 m 0.03898 0.02983   5 0.01334 0.7654 0.01759, 0.09059 -0.03
BXD62 m 0.0055979 0.00175951   5 0.00078687 0.3143 0.00306122, 0.00728008 -0.59
BXD63 m 0.01779 0.01025   5 0.00458276 0.5761 0.00402764, 0.03062 -0.39
BXD64 m 0.03946 0.01502   3 0.00867181 0.3807 0.02445, 0.05449 -0.02
BXD66 m 0.05171 0.03589   7 0.01356 0.694 0.02115, 0.12269 0.18
BXD67 m 0.0235 0.0133   4 0.00665154 0.566 0.00960239, 0.04049 -0.29
BXD69 m 0.01863 0.01507   5 0.0067402 0.8091 0.00554217, 0.04412 -0.37
BXD73 m 0.03151 0.01097   5 0.00490799 0.3483 0.01942, 0.04768 -0.16
BXD75 m 0.00768888 0.00428115   5 0.00191459 0.5568 0.003045, 0.01386 -0.56
BXD77 m 0.0259 0.01171   5 0.00523713 0.4522 0.01606, 0.046 -0.25
BXD79 m 0.06021 0.029   5 0.01297 0.4817 0.01564, 0.09014 0.32
BXD8 m 0.0335 0.01537   5 0.00687531 0.4589 0.01984, 0.05921 -0.12
BXD81 m 0.01334 0.00600341   4 0.00300171 0.4502 0.00433131, 0.01645 -0.46
BXD84 m 0.05134 0.04962   5 0.02219 0.9666 0.01529, 0.13855 0.18
BXD87 m 0.09312 0.07914   5 0.03539 0.8499 0.03249, 0.20317 0.88
BXD89 m 0.05722 0.0208   5 0.00930348 0.3636 0.03858, 0.09147 0.27
BXD90 m 0.02906 0.0144   5 0.00644062 0.4955 0.00930473, 0.04319 -0.2
C57BL/6J m 0.00703096 0.00554718   5 0.00248077 0.789 0.00159, 0.01619 -0.57
DBA/2J m 0.00977868 0.01186   5 0.00530541 1.2132 0.00017769, 0.02943 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.0199175 0.0398709409 0.098775274 -0.058940274
BXD100 m 0.0052169333 0.032554487 0.0696040362 -0.0591701695
BXD11 m 0.015869005 0.0398709409 0.094726779 -0.062988769
BXD12 m 0.15854 0.0398709409 0.237397774 0.079682226
BXD27 m 0.03848 0.0398709409 0.117337774 -0.040377774
BXD32 m 0.040476818 0.0356616537 0.1110093553 -0.0300557193
BXD34 m 0.031984 0.0356616537 0.1025165373 -0.0385485373
BXD39 m 0.022304 0.0356616537 0.0928365373 -0.0482285373
BXD40 m 0.042458 0.0356616537 0.1129905373 -0.0280745373
BXD43 m 0.3458566667 0.046038997 0.4369137808 0.2547995526
BXD45 m 0.0199612175 0.0398709409 0.0988189915 -0.0588965565
BXD48 m 0.026864 0.0356616537 0.0973965373 -0.0436685373
BXD48a m 0.01337997 0.0398709409 0.092237744 -0.065477804
BXD49 m 0.0032633825 0.0398709409 0.0821211565 -0.0755943915
BXD51 m 0.013745656 0.0356616537 0.0842781933 -0.0567868813
BXD53 m 0.045934 0.0356616537 0.1164665373 -0.0245985373
BXD55 m 0.011663456 0.0356616537 0.0821959933 -0.0588690813
BXD6 m 0.03898 0.0356616537 0.1095125373 -0.0315525373
BXD62 m 0.0055979 0.0356616537 0.0761304373 -0.0649346373
BXD63 m 0.017787528 0.0356616537 0.0883200653 -0.0527450093
BXD64 m 0.0394566667 0.046038997 0.1305137808 -0.0516004474
BXD66 m 0.0517142857 0.0301395984 0.1113251597 -0.0078965883
BXD67 m 0.0235030975 0.0398709409 0.1023608715 -0.0553546765
BXD69 m 0.018628654 0.0356616537 0.0891611913 -0.0519038833
BXD73 m 0.031506 0.0356616537 0.1020385373 -0.0390265373
BXD75 m 0.007688882 0.0356616537 0.0782214193 -0.0628436553
BXD77 m 0.025896 0.0356616537 0.0964285373 -0.0446365373
BXD79 m 0.060212 0.0356616537 0.1307445373 -0.0103205373
BXD8 m 0.033498 0.0356616537 0.1040305373 -0.0370345373
BXD81 m 0.0133353275 0.0398709409 0.0921931015 -0.0655224465
BXD84 m 0.051336 0.0356616537 0.1218685373 -0.0191965373
BXD87 m 0.093116 0.0356616537 0.1636485373 0.0225834627
BXD89 m 0.057222 0.0356616537 0.1277545373 -0.0133105373
BXD90 m 0.029064946 0.0356616537 0.0995974833 -0.0414675913
C57BL/6J m 0.007030956 0.0356616537 0.0775634933 -0.0635015813
DBA/2J m 0.009778676 0.0356616537 0.0803112133 -0.0607538613




  GWAS USING LINEAR MIXED MODELS