Project measure / variable:   Schoonjans1   TUDCA_liver_HFD

ID, description, units MPD:112850   TUDCA_liver_HFD   bile acid tauroursodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauroursodeoxycholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means2.1412   ng/mL
Median of the strain means1.8045   ng/mL
SD of the strain means± 1.0673
Coefficient of variation (CV)0.4984
Min–max range of strain means0.87009   –   5.7347   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 187.0213 5.3435 5.6829 < 0.0001
Residuals 141 132.5782 0.9403


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.0686 1.1663   5 0.5216 0.3801 1.8048, 4.4946 0.87
BXD100 m 1.3381 0.68797   7 0.26003 0.5141 0.56322, 2.2748 -0.75
BXD11 m 0.87009 0.06447   3 0.03722 0.0741 0.79861, 0.92385 -1.19
BXD12 m 2.8218 1.3884   4 0.69421 0.492 1.4294, 4.6858 0.64
BXD27 m 2.9064 1.2716   5 0.56867 0.4375 1.8657, 4.3392 0.72
BXD32 m 3.1811 1.1399   4 0.56997 0.3583 1.7789, 4.51 0.97
BXD34 m 5.021 3.2207   4 1.6103 0.6414 2.4573, 9.6949 2.7
BXD39 m 1.8273 0.69431   5 0.3105 0.38 1.1592, 2.7861 -0.29
BXD40 m 3.0956 1.5122   5 0.67629 0.4885 1.7828, 5.5388 0.89
BXD43 m 1.7338 0.97193   5 0.43466 0.5606 0.66097, 3.2861 -0.38
BXD45 m 5.7347 1.4829   5 0.66318 0.2586 3.4265, 7.0494 3.37
BXD48 m 1.7569 0.43932   5 0.19647 0.2501 1.0459, 2.2258 -0.36
BXD48a m 2.7968 0.98339   5 0.43978 0.3516 1.7618, 4.1421 0.61
BXD49 m 2.1542 0.75285   5 0.33668 0.3495 1.2352, 2.9315 0.01
BXD51 m 2.4074 0.62616   5 0.28003 0.2601 1.7014, 3.2169 0.25
BXD53 m 1.5977 0.32013   5 0.14317 0.2004 1.1519, 1.9821 -0.51
BXD55 m 1.8912 0.91898   5 0.41098 0.4859 1.17, 3.1145 -0.23
BXD6 m 1.2673 0.44669   5 0.19977 0.3525 0.839, 1.9959 -0.82
BXD62 m 1.6145 0.62497   5 0.2795 0.3871 1.1679, 2.718 -0.49
BXD63 m 1.0127 0.32616   5 0.14586 0.3221 0.62556, 1.5052 -1.06
BXD64 m 2.0661 0.82786   5 0.37023 0.4007 1.0844, 2.9089 -0.07
BXD66 m 1.6894 0.80729   9 0.2691 0.4779 0.80326, 3.1713 -0.42
BXD67 m 1.2827 0.27962   5 0.12505 0.218 0.99329, 1.7393 -0.8
BXD69 m 1.2384 0.82242   5 0.3678 0.6641 0.61065, 2.633 -0.85
BXD73 m 1.4621 0.45306   5 0.20262 0.3099 0.88303, 2.1426 -0.64
BXD75 m 3.0744 1.1348   4 0.56741 0.3691 1.9723, 4.5521 0.87
BXD77 m 1.7816 0.44222   5 0.19777 0.2482 1.2179, 2.3736 -0.34
BXD79 m 1.1827 0.80267   5 0.35896 0.6787 0.49363, 2.5274 -0.9
BXD8 m 1.621 0.30857   4 0.15429 0.1904 1.2797, 1.9358 -0.49
BXD81 m 0.96075 0.11694   5 0.0523 0.1217 0.78871, 1.0659 -1.11
BXD84 m 0.96798 0.36405   5 0.16281 0.3761 0.65114, 1.5756 -1.1
BXD87 m 2.3628 0.952   5 0.42575 0.4029 1.1898, 3.6079 0.21
BXD89 m 3.3022 1.43   5 0.63952 0.433 1.53, 5.5159 1.09
BXD90 m 2.0123 0.89802   3 0.51847 0.4463 1.2994, 3.0209 -0.12
C57BL/6J m 2.361 1.0572   5 0.47278 0.4478 0.87894, 3.7237 0.21
DBA/2J m 1.622 0.36921   5 0.16512 0.2276 1.0795, 2.0516 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.06856 0.433652156 3.9258606024 2.2112593976
BXD100 m 1.3381014286 0.3665029648 2.0626526803 0.6135501769
BXD11 m 0.87009 0.5598425261 1.9768603186 -0.2366803186
BXD12 m 2.82185 0.4848378498 3.7803412121 1.8633587879
BXD27 m 2.90636 0.433652156 3.7636606024 2.0490593976
BXD32 m 3.1811 0.4848378498 4.1395912121 2.2226087879
BXD34 m 5.02095 0.4848378498 5.9794412121 4.0624587879
BXD39 m 1.82732 0.433652156 2.6846206024 0.9700193976
BXD40 m 3.09556 0.433652156 3.9528606024 2.2382593976
BXD43 m 1.733754 0.433652156 2.5910546024 0.8764533976
BXD45 m 5.73466 0.433652156 6.5919606024 4.8773593976
BXD48 m 1.75688 0.433652156 2.6141806024 0.8995793976
BXD48a m 2.79682 0.433652156 3.6541206024 1.9395193976
BXD49 m 2.15422 0.433652156 3.0115206024 1.2969193976
BXD51 m 2.4074 0.433652156 3.2647006024 1.5500993976
BXD53 m 1.59772 0.433652156 2.4550206024 0.7404193976
BXD55 m 1.89124 0.433652156 2.7485406024 1.0339393976
BXD6 m 1.267334 0.433652156 2.1246346024 0.4100333976
BXD62 m 1.61452 0.433652156 2.4718206024 0.7572193976
BXD63 m 1.012696 0.433652156 1.8699966024 0.1553953976
BXD64 m 2.06612 0.433652156 2.9234206024 1.2088193976
BXD66 m 1.68936 0.3232252332 2.3283541414 1.0503658586
BXD67 m 1.282678 0.433652156 2.1399786024 0.4253773976
BXD69 m 1.238352 0.433652156 2.0956526024 0.3810513976
BXD73 m 1.462126 0.433652156 2.3194266024 0.6048253976
BXD75 m 3.07445 0.4848378498 4.0329412121 2.1159587879
BXD77 m 1.78156 0.433652156 2.6388606024 0.9242593976
BXD79 m 1.182656 0.433652156 2.0399566024 0.3253553976
BXD8 m 1.621025 0.4848378498 2.5795162121 0.6625337879
BXD81 m 0.960746 0.433652156 1.8180466024 0.1034453976
BXD84 m 0.967978 0.433652156 1.8252786024 0.1106773976
BXD87 m 2.3628 0.433652156 3.2201006024 1.5054993976
BXD89 m 3.30224 0.433652156 4.1595406024 2.4449393976
BXD90 m 2.0123333333 0.5598425261 3.1191036519 0.9055630147
C57BL/6J m 2.361008 0.433652156 3.2183086024 1.5037073976
DBA/2J m 1.622 0.433652156 2.4793006024 0.7646993976




  GWAS USING LINEAR MIXED MODELS