Project measure / variable:   Schoonjans1   TUDCA_liver_CD

ID, description, units MPD:112849   TUDCA_liver_CD   bile acid tauroursodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauroursodeoxycholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.92606   ng/mL
Median of the strain means0.86822   ng/mL
SD of the strain means± 0.30587
Coefficient of variation (CV)0.3303
Min–max range of strain means0.51124   –   1.6837   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 16.3043 0.4658 4.1251 < 0.0001
Residuals 134 15.1321 0.1129


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.59619 0.08513   4 0.04256 0.1428 0.48814, 0.67482 -1.08
BXD100 m 0.92853 0.21904   6 0.08942 0.2359 0.61811, 1.2639 0.01
BXD11 m 0.9619 0.3859   4 0.19295 0.4012 0.41571, 1.3085 0.12
BXD12 m 1.499 0.4429   4 0.22145 0.2955 0.87894, 1.8224 1.87
BXD27 m 1.1857 0.32419   4 0.16209 0.2734 0.79228, 1.5313 0.85
BXD32 m 0.59915 0.13589   5 0.06077 0.2268 0.4695, 0.7667 -1.07
BXD34 m 0.82777 0.1036   5 0.04633 0.1252 0.69324, 0.9385 -0.32
BXD39 m 0.9718 0.36923   5 0.16513 0.38 0.5487, 1.4327 0.15
BXD40 m 0.61031 0.16119   5 0.07209 0.2641 0.39228, 0.83039 -1.03
BXD43 m 0.75385 0.54824   3 0.31653 0.7273 0.41, 1.3861 -0.56
BXD45 m 0.97169 0.13456   4 0.06728 0.1385 0.77547, 1.0715 0.15
BXD48 m 1.0745 0.40951   5 0.18314 0.3811 0.41017, 1.4445 0.49
BXD48a m 0.86909 0.40417   4 0.20209 0.4651 0.46138, 1.2587 -0.19
BXD49 m 0.6865 0.3044   4 0.1522 0.4434 0.46365, 1.1365 -0.78
BXD51 m 1.0499 0.15288   5 0.06837 0.1456 0.88684, 1.2698 0.4
BXD53 m 0.6778 0.23144   5 0.1035 0.3415 0.36845, 0.96501 -0.81
BXD55 m 0.7901 0.30597   5 0.13683 0.3873 0.3896, 1.1098 -0.44
BXD6 m 1.2679 0.79991   5 0.35773 0.6309 0.69521, 2.6206 1.12
BXD62 m 1.1291 0.45242   5 0.20233 0.4007 0.68273, 1.8108 0.66
BXD63 m 0.62388 0.14832   5 0.06633 0.2377 0.42053, 0.76846 -0.99
BXD64 m 1.3831 0.63337   3 0.36568 0.458 0.72418, 1.9874 1.49
BXD66 m 1.6378 0.52478   7 0.19835 0.3204 0.99617, 2.434 2.33
BXD67 m 0.75922 0.33774   4 0.16887 0.4449 0.44867, 1.0753 -0.55
BXD69 m 0.84834 0.27496   5 0.12297 0.3241 0.49218, 1.1749 -0.25
BXD73 m 0.56108 0.13776   5 0.06161 0.2455 0.34834, 0.68058 -1.19
BXD75 m 0.51124 0.05904   5 0.0264 0.1155 0.43651, 0.60155 -1.36
BXD77 m 0.78442 0.38404   5 0.17175 0.4896 0.3494, 1.3883 -0.46
BXD79 m 1.6837 0.51699   5 0.23121 0.3071 0.90339, 2.3405 2.48
BXD8 m 0.58278 0.18801   5 0.08408 0.3226 0.47827, 0.9169 -1.12
BXD81 m 0.86735 0.26881   4 0.1344 0.3099 0.49222, 1.1173 -0.19
BXD84 m 0.87959 0.3404   5 0.15223 0.387 0.47345, 1.3433 -0.15
BXD87 m 0.87368 0.15459   5 0.06913 0.1769 0.74181, 1.0569 -0.17
BXD89 m 1.2572 0.30774   5 0.13763 0.2448 0.78106, 1.5713 1.08
BXD90 m 1.2424 0.25186   5 0.11263 0.2027 0.90491, 1.5593 1.03
C57BL/6J m 0.71131 0.06967   5 0.03116 0.0979 0.62343, 0.77952 -0.7
DBA/2J m 0.68033 0.15315   5 0.06849 0.2251 0.4668, 0.88878 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.5961875 0.1680226705 0.9285070656 0.2638679344
BXD100 m 0.928525 0.137189936 1.1998627891 0.6571872109
BXD11 m 0.961895 0.1680226705 1.2942145656 0.6295754344
BXD12 m 1.498985 0.1680226705 1.8313045656 1.1666654344
BXD27 m 1.185695 0.1680226705 1.5180145656 0.8533754344
BXD32 m 0.59915 0.1502840452 0.8963856556 0.3019143444
BXD34 m 0.827772 0.1502840452 1.1250076556 0.5305363444
BXD39 m 0.971798 0.1502840452 1.2690336556 0.6745623444
BXD40 m 0.610312 0.1502840452 0.9075476556 0.3130763444
BXD43 m 0.7538533333 0.1940158681 1.1375829146 0.370123752
BXD45 m 0.9716875 0.1680226705 1.3040070656 0.6393679344
BXD48 m 1.074494 0.1502840452 1.3717296556 0.7772583444
BXD48a m 0.8690925 0.1680226705 1.2014120656 0.5367729344
BXD49 m 0.6865 0.1680226705 1.0188195656 0.3541804344
BXD51 m 1.04988 0.1502840452 1.3471156556 0.7526443444
BXD53 m 0.677798 0.1502840452 0.9750336556 0.3805623444
BXD55 m 0.790102 0.1502840452 1.0873376556 0.4928663444
BXD6 m 1.267904 0.1502840452 1.5651396556 0.9706683444
BXD62 m 1.129084 0.1502840452 1.4263196556 0.8318483444
BXD63 m 0.623882 0.1502840452 0.9211176556 0.3266463444
BXD64 m 1.38306 0.1940158681 1.7667895813 0.9993304187
BXD66 m 1.6377671429 0.1270132002 1.8889771218 1.3865571639
BXD67 m 0.7592225 0.1680226705 1.0915420656 0.4269029344
BXD69 m 0.84834 0.1502840452 1.1455756556 0.5511043444
BXD73 m 0.56108 0.1502840452 0.8583156556 0.2638443444
BXD75 m 0.511244 0.1502840452 0.8084796556 0.2140083444
BXD77 m 0.784418 0.1502840452 1.0816536556 0.4871823444
BXD79 m 1.683698 0.1502840452 1.9809336556 1.3864623444
BXD8 m 0.582778 0.1502840452 0.8800136556 0.2855423444
BXD81 m 0.867345 0.1680226705 1.1996645656 0.5350254344
BXD84 m 0.879594 0.1502840452 1.1768296556 0.5823583444
BXD87 m 0.87368 0.1502840452 1.1709156556 0.5764443444
BXD89 m 1.257232 0.1502840452 1.5544676556 0.9599963444
BXD90 m 1.242362 0.1502840452 1.5395976556 0.9451263444
C57BL/6J m 0.711306 0.1502840452 1.0085416556 0.4140703444
DBA/2J m 0.680332 0.1502840452 0.9775676556 0.3830963444




  GWAS USING LINEAR MIXED MODELS