Project measure / variable:   Schoonjans1   TLCA_liver_HFD

ID, description, units MPD:112848   TLCA_liver_HFD   bile acid taurolithocholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   12 strains     sex: m     age: 29wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurolithocholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested12 strains
Mean of the strain means0.05134   ng/mL
Median of the strain means0.04848   ng/mL
SD of the strain means± 0.00906406
Coefficient of variation (CV)0.1766
Min–max range of strain means0.04007   –   0.07305   ng/mL
Mean sample size per strain2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 0.0016 0.0002 0.9795 0.4716
Residuals 21 0.005 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.05841 0.00285882   5 0.0012785 0.0489 0.05546, 0.06243 0.78
BXD11 m 0.04487 0.0   1   0.0 0.0 0.04487, 0.04487 -0.71
BXD45 m 0.05436 0.0203   2   0.01435 0.3735 0.04, 0.06871 0.33
BXD48 m 0.05589 0.02097   2   0.01483 0.3753 0.04106, 0.07072 0.5
BXD49 m 0.04796 0.00231743   4 0.00115871 0.0483 0.04562, 0.05053 -0.37
BXD53 m 0.04163 0.0   1   0.0 0.0 0.04163, 0.04163 -1.07
BXD55 m 0.04007 0.0   1   0.0 0.0 0.04007, 0.04007 -1.24
BXD69 m 0.04899 0.01521   5 0.00680214 0.3105 0.03723, 0.07281 -0.26
BXD75 m 0.07305 0.0364   3 0.02101 0.4982 0.03814, 0.11077 2.4
BXD81 m 0.05705 0.01086   5 0.00485503 0.1903 0.04386, 0.06785 0.63
C57BL/6J m 0.04711 0.00383728   3 0.00221545 0.0815 0.04273, 0.04988 -0.47
DBA/2J m 0.04665 0.0   1   0.0 0.0 0.04665, 0.04665 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.05841 0.0068843482 0.0727267859 0.0440932141
BXD45 m 0.054355 0.0108851103 0.0769918261 0.0317181739
BXD48 m 0.05589 0.0108851103 0.0785268261 0.0332531739
BXD49 m 0.04796 0.0076969353 0.0639666532 0.0319533468
BXD69 m 0.048992 0.0068843482 0.0633087859 0.0346752141
BXD75 m 0.0730533333 0.0088876554 0.0915362245 0.0545704422
BXD81 m 0.057046 0.0068843482 0.0713627859 0.0427292141
C57BL/6J m 0.04711 0.0088876554 0.0655928911 0.0286271089




  GWAS USING LINEAR MIXED MODELS