Project measure / variable:   Schoonjans1   TLCA_liver_CD

ID, description, units MPD:112847   TLCA_liver_CD   bile acid taurolithocholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   20 strains     sex: m     age: 29wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurolithocholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested20 strains
Mean of the strain means0.05641   ng/mL
Median of the strain means0.05206   ng/mL
SD of the strain means± 0.02094
Coefficient of variation (CV)0.3711
Min–max range of strain means0.03737   –   0.1228   ng/mL
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 0.0025 0.0002 1.4091 0.199
Residuals 39 0.0054 0.0001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.04509 0.00394462   3 0.00227743 0.0875 0.0406, 0.04801 -0.54
BXD12 m 0.10066 0.0   1   0.0 0.0 0.10066, 0.10066 2.11
BXD27 m 0.04633 0.0   1   0.0 0.0 0.04633, 0.04633 -0.48
BXD32 m 0.04168 0.00365433   3 0.00210983 0.0877 0.03905, 0.04585 -0.7
BXD34 m 0.04044 0.0   1   0.0 0.0 0.04044, 0.04044 -0.76
BXD43 m 0.1228 0.0   1   0.0 0.0 0.1228, 0.1228 3.17
BXD45 m 0.05969 0.00508972   4 0.00254486 0.0853 0.05232, 0.06331 0.16
BXD48 m 0.06962 0.01754   2   0.0124 0.2519 0.05722, 0.08202 0.63
BXD48a m 0.03967 0.0   1   0.0 0.0 0.03967, 0.03967 -0.8
BXD49 m 0.05228 0.00768319   4 0.00384159 0.147 0.04222, 0.06012 -0.2
BXD55 m 0.06081 0.02257   5 0.01009 0.3711 0.04054, 0.09727 0.21
BXD63 m 0.04734 0.00920067   5 0.00411467 0.1944 0.03871, 0.05849 -0.43
BXD69 m 0.061 0.01631   5 0.00729209 0.2673 0.04123, 0.08559 0.22
BXD73 m 0.04795 0.00717959   5 0.00321081 0.1497 0.0383, 0.05719 -0.4
BXD75 m 0.0535 0.00705272   3 0.00407189 0.1318 0.04887, 0.06162 -0.14
BXD79 m 0.05436 0.01552   3 0.00896052 0.2855 0.03887, 0.06991 -0.1
BXD8 m 0.03737 0.0   1   0.0 0.0 0.03737, 0.03737 -0.91
BXD81 m 0.05183 0.00834226   4 0.00417113 0.161 0.04077, 0.06048 -0.22
BXD87 m 0.04325 0.0039414   3 0.00227557 0.0911 0.03886, 0.04649 -0.63
C57BL/6J m 0.05259 0.00949503   4 0.00474751 0.1805 0.04268, 0.06468 -0.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.0450866667 0.0067666446 0.0587734972 0.0313998361
BXD32 m 0.0416766667 0.0067666446 0.0553634972 0.0279898361
BXD45 m 0.0596925 0.0058600861 0.071545643 0.047839357
BXD48 m 0.06962 0.0082874133 0.0863828755 0.0528571245
BXD49 m 0.052275 0.0058600861 0.064128143 0.040421857
BXD55 m 0.060808 0.0052414204 0.0714097734 0.0502062266
BXD63 m 0.04734 0.0052414204 0.0579417734 0.0367382266
BXD69 m 0.061 0.0052414204 0.0716017734 0.0503982266
BXD73 m 0.047948 0.0052414204 0.0585497734 0.0373462266
BXD75 m 0.0535033333 0.0067666446 0.0671901639 0.0398165028
BXD79 m 0.0543633333 0.0067666446 0.0680501639 0.0406765028
BXD81 m 0.051825 0.0058600861 0.063678143 0.039971857
BXD87 m 0.0432466667 0.0067666446 0.0569334972 0.0295598361
C57BL/6J m 0.0525925 0.0058600861 0.064445643 0.040739357




  GWAS USING LINEAR MIXED MODELS