Project measure / variable:   Schoonjans1   TCDCA_liver_CD

ID, description, units MPD:112841   TCDCA_liver_CD   bile acid taurochenodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurochenodeoxycholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means1.8229   ng/mL
Median of the strain means1.6801   ng/mL
SD of the strain means± 0.54156
Coefficient of variation (CV)0.2971
Min–max range of strain means0.95492   –   3.2296   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 47.0903 1.3454 5.7808 < 0.0001
Residuals 134 31.1876 0.2327


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.3167 0.3008   4 0.1504 0.2284 1.0837, 1.7578 -0.93
BXD100 m 1.5421 0.34032   6 0.13894 0.2207 1.0504, 1.9514 -0.52
BXD11 m 1.6725 0.06143   4 0.03072 0.0367 1.6015, 1.7285 -0.28
BXD12 m 3.2296 1.1286   4 0.56428 0.3494 2.5468, 4.9172 2.6
BXD27 m 2.5577 0.53354   4 0.26677 0.2086 2.1275, 3.2647 1.36
BXD32 m 1.5095 0.25707   5 0.11496 0.1703 1.3077, 1.8719 -0.58
BXD34 m 2.6832 0.39782   5 0.17791 0.1483 2.1228, 3.2386 1.59
BXD39 m 1.6954 0.43146   5 0.19295 0.2545 1.2403, 2.233 -0.24
BXD40 m 1.2345 0.16979   5 0.07593 0.1375 1.0802, 1.4877 -1.09
BXD43 m 1.6613 1.2386   3 0.71513 0.7456 0.74268, 3.07 -0.3
BXD45 m 2.2794 0.31379   4 0.15689 0.1377 2.0001, 2.6905 0.84
BXD48 m 2.6148 1.0989   5 0.49146 0.4203 1.6148, 4.4312 1.46
BXD48a m 2.0979 0.35589   4 0.17794 0.1696 1.7555, 2.517 0.51
BXD49 m 1.9696 0.40893   4 0.20446 0.2076 1.499, 2.4491 0.27
BXD51 m 1.554 0.58994   5 0.26383 0.3796 0.88967, 2.4826 -0.5
BXD53 m 1.626 0.54292   5 0.2428 0.3339 0.96971, 2.2492 -0.36
BXD55 m 1.869 0.36627   5 0.1638 0.196 1.2772, 2.155 0.09
BXD6 m 1.4772 0.39767   5 0.17784 0.2692 1.0079, 1.9938 -0.64
BXD62 m 1.8171 0.24258   5 0.10848 0.1335 1.5444, 2.1562 -0.01
BXD63 m 0.95492 0.15592   5 0.06973 0.1633 0.79033, 1.1595 -1.6
BXD64 m 2.2931 0.45644   3 0.26353 0.1991 1.91, 2.7981 0.87
BXD66 m 2.1942 0.45755   7 0.17294 0.2085 1.589, 2.874 0.69
BXD67 m 1.0124 0.16018   4 0.08009 0.1582 0.85847, 1.2083 -1.5
BXD69 m 2.4611 0.72603   5 0.32469 0.295 1.5789, 3.1408 1.18
BXD73 m 1.4203 0.26522   5 0.11861 0.1867 1.1079, 1.6873 -0.74
BXD75 m 1.5511 0.18902   5 0.08453 0.1219 1.2586, 1.7224 -0.5
BXD77 m 1.8876 0.38844   5 0.17372 0.2058 1.4974, 2.372 0.12
BXD79 m 2.8179 0.82311   5 0.3681 0.2921 2.0125, 4.1529 1.84
BXD8 m 1.4101 0.30498   5 0.13639 0.2163 1.0869, 1.8182 -0.76
BXD81 m 1.2508 0.33941   4 0.1697 0.2713 0.83667, 1.6567 -1.06
BXD84 m 1.405 0.37235   5 0.16652 0.265 1.0428, 1.8693 -0.77
BXD87 m 1.432 0.14069   5 0.06292 0.0982 1.1836, 1.5276 -0.72
BXD89 m 2.4511 0.43698   5 0.19543 0.1783 1.9097, 3.0822 1.16
BXD90 m 1.754 0.38704   5 0.17309 0.2207 1.4184, 2.3426 -0.13
C57BL/6J m 1.6877 0.22755   5 0.10177 0.1348 1.4088, 1.9525 -0.25
DBA/2J m 1.2341 0.23807   5 0.10647 0.1929 0.96633, 1.563 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.316725 0.2412174468 1.7938110795 0.8396389205
BXD100 m 1.5421333333 0.1969532205 1.9316724861 1.1525941806
BXD11 m 1.672475 0.2412174468 2.1495610795 1.1953889205
BXD12 m 3.22965 0.2412174468 3.7067360795 2.7525639205
BXD27 m 2.5577 0.2412174468 3.0347860795 2.0806139205
BXD32 m 1.5095 0.2157514433 1.936218762 1.082781238
BXD34 m 2.68324 0.2157514433 3.109958762 2.256521238
BXD39 m 1.69538 0.2157514433 2.122098762 1.268661238
BXD40 m 1.23446 0.2157514433 1.661178762 0.807741238
BXD43 m 1.6612933333 0.2785339156 2.2121848862 1.1104017805
BXD45 m 2.279375 0.2412174468 2.7564610795 1.8022889205
BXD48 m 2.61478 0.2157514433 3.041498762 2.188061238
BXD48a m 2.097875 0.2412174468 2.5749610795 1.6207889205
BXD49 m 1.969575 0.2412174468 2.4466610795 1.4924889205
BXD51 m 1.554014 0.2157514433 1.980732762 1.127295238
BXD53 m 1.625982 0.2157514433 2.052700762 1.199263238
BXD55 m 1.86898 0.2157514433 2.295698762 1.442261238
BXD6 m 1.47718 0.2157514433 1.903898762 1.050461238
BXD62 m 1.81708 0.2157514433 2.243798762 1.390361238
BXD63 m 0.954916 0.2157514433 1.381634762 0.528197238
BXD64 m 2.2930666667 0.2785339156 2.8439582195 1.7421751138
BXD66 m 2.1942142857 0.1823432503 2.554857463 1.8335711085
BXD67 m 1.0123775 0.2412174468 1.4894635795 0.5352914205
BXD69 m 2.46106 0.2157514433 2.887778762 2.034341238
BXD73 m 1.42034 0.2157514433 1.847058762 0.993621238
BXD75 m 1.55106 0.2157514433 1.977778762 1.124341238
BXD77 m 1.8876 0.2157514433 2.314318762 1.460881238
BXD79 m 2.81788 0.2157514433 3.244598762 2.391161238
BXD8 m 1.4101 0.2157514433 1.836818762 0.983381238
BXD81 m 1.2508425 0.2412174468 1.7279285795 0.7737564205
BXD84 m 1.40498 0.2157514433 1.831698762 0.978261238
BXD87 m 1.43198 0.2157514433 1.858698762 1.005261238
BXD89 m 2.4511 0.2157514433 2.877818762 2.024381238
BXD90 m 1.75404 0.2157514433 2.180758762 1.327321238
C57BL/6J m 1.6877 0.2157514433 2.114418762 1.260981238
DBA/2J m 1.234126 0.2157514433 1.660844762 0.807407238




  GWAS USING LINEAR MIXED MODELS