Project measure / variable:   Schoonjans1   TaMCA_liver_HFD

ID, description, units MPD:112836   TaMCA_liver_HFD   bile acid tauro-α-muricholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauro-α-muricholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means7.8384   ng/mL
Median of the strain means7.0902   ng/mL
SD of the strain means± 2.9164
Coefficient of variation (CV)0.3721
Min–max range of strain means3.5719   –   16.902   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1359.3578 38.8388 3.6236 < 0.0001
Residuals 141 1511.2923 10.7184


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 9.5984 5.0831   5 2.2732 0.5296 5.1091, 16.726 0.6
BXD100 m 6.1277 2.7037   7 1.0219 0.4412 2.704, 10.183 -0.59
BXD11 m 3.5719 0.87208   3 0.5035 0.2442 2.6897, 4.4335 -1.46
BXD12 m 7.5823 3.9295   4 1.9648 0.5183 3.3289, 12.825 -0.09
BXD27 m 11.39 4.7698   5 2.1331 0.4188 6.8405, 19.21 1.22
BXD32 m 10.371 1.8476   4 0.92382 0.1781 8.0107, 12.277 0.87
BXD34 m 16.902 7.1486   4 3.5743 0.4229 11.884, 27.137 3.11
BXD39 m 9.5398 3.2043   5 1.433 0.3359 7.0597, 14.431 0.58
BXD40 m 8.3336 2.8518   5 1.2754 0.3422 5.8977, 12.926 0.17
BXD43 m 7.1118 3.0696   5 1.3728 0.4316 4.5213, 11.606 -0.25
BXD45 m 14.589 3.1298   5 1.3997 0.2145 10.222, 18.456 2.31
BXD48 m 7.7492 2.4692   5 1.1043 0.3186 4.0584, 11.011 -0.03
BXD48a m 11.194 4.6471   5 2.0782 0.4151 6.1805, 17.913 1.15
BXD49 m 6.3504 2.9912   5 1.3377 0.471 2.911, 9.1329 -0.51
BXD51 m 8.3052 1.8166   5 0.81242 0.2187 7.1874, 11.529 0.16
BXD53 m 6.0639 1.6104   5 0.72019 0.2656 3.5377, 7.3599 -0.61
BXD55 m 7.0686 4.3346   5 1.9385 0.6132 3.1413, 13.688 -0.26
BXD6 m 3.9181 0.59411   5 0.26569 0.1516 3.3206, 4.7693 -1.34
BXD62 m 6.8275 2.198   5 0.98299 0.3219 4.6209, 9.653 -0.35
BXD63 m 4.2219 1.0113   5 0.45228 0.2395 3.1108, 5.4469 -1.24
BXD64 m 9.3135 3.864   5 1.728 0.4149 5.6124, 14.673 0.51
BXD66 m 6.3113 3.1961   9 1.0654 0.5064 3.0037, 13.35 -0.52
BXD67 m 6.1093 1.2135   5 0.54271 0.1986 4.065, 7.3004 -0.59
BXD69 m 5.8969 4.2589   5 1.9046 0.7222 2.3345, 13.148 -0.67
BXD73 m 5.729 1.4942   5 0.66824 0.2608 4.4323, 8.1041 -0.72
BXD75 m 11.725 4.8596   4 2.4298 0.4145 7.7477, 17.937 1.33
BXD77 m 7.6298 2.7386   5 1.2247 0.3589 5.1216, 11.492 -0.07
BXD79 m 5.1998 4.0434   5 1.8083 0.7776 1.8041, 12.107 -0.9
BXD8 m 6.1006 2.0112   4 1.0056 0.3297 4.0671, 8.7127 -0.6
BXD81 m 6.2368 2.0737   5 0.92741 0.3325 3.9776, 9.4655 -0.55
BXD84 m 4.3012 1.5524   5 0.69424 0.3609 2.5918, 6.6117 -1.21
BXD87 m 5.9376 2.422   5 1.0832 0.4079 3.4114, 9.6763 -0.65
BXD89 m 9.9958 4.1448   5 1.8536 0.4147 7.1826, 17.253 0.74
BXD90 m 7.6689 3.0325   3 1.7508 0.3954 5.4303, 11.12 -0.06
C57BL/6J m 10.916 4.3559   5 1.948 0.399 5.1609, 17.425 1.06
DBA/2J m 6.2956 2.2687   5 1.0146 0.3604 4.0576, 9.7752 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 9.59842 1.4641301414 12.49290498 6.70393502
BXD100 m 6.1277428571 1.2374158185 8.5740291532 3.6814565611
BXD11 m 3.5719 1.8901838848 7.3086640411 -0.1648640411
BXD12 m 7.58225 1.636947262 10.8183825876 4.3461174124
BXD27 m 11.38986 1.4641301414 14.28434498 8.49537502
BXD32 m 10.371275 1.636947262 13.6074075876 7.1351424124
BXD34 m 16.9025 1.636947262 20.1386325876 13.6663674124
BXD39 m 9.53978 1.4641301414 12.43426498 6.64529502
BXD40 m 8.33362 1.4641301414 11.22810498 5.43913502
BXD43 m 7.11178 1.4641301414 10.00626498 4.21729502
BXD45 m 14.5892 1.4641301414 17.48368498 11.69471502
BXD48 m 7.74918 1.4641301414 10.64366498 4.85469502
BXD48a m 11.19402 1.4641301414 14.08850498 8.29953502
BXD49 m 6.35044 1.4641301414 9.24492498 3.45595502
BXD51 m 8.3052 1.4641301414 11.19968498 5.41071502
BXD53 m 6.06386 1.4641301414 8.95834498 3.16937502
BXD55 m 7.0686 1.4641301414 9.96308498 4.17411502
BXD6 m 3.9181 1.4641301414 6.81258498 1.02361502
BXD62 m 6.8275 1.4641301414 9.72198498 3.93301502
BXD63 m 4.22194 1.4641301414 7.11642498 1.32745502
BXD64 m 9.31352 1.4641301414 12.20800498 6.41903502
BXD66 m 6.3112888889 1.0912981747 8.4687106139 4.1538671639
BXD67 m 6.1093 1.4641301414 9.00378498 3.21481502
BXD69 m 5.89686 1.4641301414 8.79134498 3.00237502
BXD73 m 5.72896 1.4641301414 8.62344498 2.83447502
BXD75 m 11.72535 1.636947262 14.9614825876 8.4892174124
BXD77 m 7.62976 1.4641301414 10.52424498 4.73527502
BXD79 m 5.19978 1.4641301414 8.09426498 2.30529502
BXD8 m 6.10065 1.636947262 9.3367825876 2.8645174124
BXD81 m 6.23682 1.4641301414 9.13130498 3.34233502
BXD84 m 4.30116 1.4641301414 7.19564498 1.40667502
BXD87 m 5.9376 1.4641301414 8.83208498 3.04311502
BXD89 m 9.99582 1.4641301414 12.89030498 7.10133502
BXD90 m 7.6689 1.8901838848 11.4056640411 3.9321359589
C57BL/6J m 10.91598 1.4641301414 13.81046498 8.02149502
DBA/2J m 6.29564 1.4641301414 9.19012498 3.40115502




  GWAS USING LINEAR MIXED MODELS