Project measure / variable:   Schoonjans1   GUDCA_liver_HFD

ID, description, units MPD:112830   GUDCA_liver_HFD   bile acid glycoursodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   32 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid glycoursodeoxycholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested32 strains
Mean of the strain means0.00303672   ng/mL
Median of the strain means0.00211496   ng/mL
SD of the strain means± 0.00295964
Coefficient of variation (CV)0.9746
Min–max range of strain means0.00096885   –   0.01643   ng/mL
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 29 0.0003 0.0 2.8253 < 0.0001
Residuals 91 0.0004 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.0056001 0.00204025   5 0.00091243 0.3643 0.00372024, 0.00884848 0.87
BXD11 m 0.01643 0.0   1   0.0 0.0 0.01643, 0.01643 4.53
BXD12 m 0.00317975 0.00281439   4 0.0014072 0.8851 0.00140118, 0.00735265 0.05
BXD27 m 0.00121975 0.00049674   2   0.00035125 0.4072 0.0008685, 0.001571 -0.61
BXD32 m 0.00321028 0.00092074   4 0.00046037 0.2868 0.0024006, 0.00445382 0.06
BXD34 m 0.00778582 0.00458218   4 0.00229109 0.5885 0.00390856, 0.01432 1.6
BXD39 m 0.00578203 0.00644544   5 0.00288249 1.1147 0.00082759, 0.01686 0.93
BXD40 m 0.00491349 0.00320313   5 0.00143248 0.6519 0.00132572, 0.00978641 0.63
BXD43 m 0.00098288 0.00011764   2   8.319e-05 0.1197 0.0008997, 0.00106607 -0.69
BXD45 m 0.00438719 0.00120439   5 0.00053862 0.2745 0.00278827, 0.00567932 0.46
BXD48 m 0.00200764 0.00112051   4 0.00056026 0.5581 0.00100701, 0.00352239 -0.35
BXD48a m 0.00222228 0.00066441   5 0.00029713 0.299 0.00148515, 0.00325558 -0.28
BXD49 m 0.00252088 0.00068406   4 0.00034203 0.2714 0.00180982, 0.00338279 -0.17
BXD53 m 0.00118066 0.00019828   5 8.867e-05 0.1679 0.00096386, 0.00146342 -0.63
BXD55 m 0.00333271 0.0019463   5 0.00087041 0.584 0.00119704, 0.00582 0.1
BXD6 m 0.00312299 0.001293   5 0.00057825 0.414 0.00167001, 0.00451049 0.03
BXD62 m 0.00135666 0.00091903   4 0.00045951 0.6774 0.0008209, 0.00273273 -0.57
BXD63 m 0.00128133 0.00050141   4 0.00025071 0.3913 0.00088945, 0.00195328 -0.59
BXD64 m 0.00246933 0.0008343   3 0.00048168 0.3379 0.00177632, 0.00339537 -0.19
BXD67 m 0.00154382 0.00081206   5 0.00036316 0.526 0.00087262, 0.00244186 -0.5
BXD69 m 0.00133196 0.00038916   4 0.00019458 0.2922 0.00094124, 0.00167497 -0.58
BXD73 m 0.00263704 0.00093068   4 0.00046534 0.3529 0.00144231, 0.00368528 -0.14
BXD75 m 0.00127387 0.00032158   4 0.00016079 0.2524 0.00108325, 0.00175516 -0.6
BXD77 m 0.0048204 0.00250304   4 0.00125152 0.5193 0.0012674, 0.00708955 0.6
BXD79 m 0.00110242 0.00027731   2   0.00019609 0.2515 0.00090634, 0.00129851 -0.65
BXD8 m 0.00193489 0.0007886   3 0.0004553 0.4076 0.00109901, 0.00266566 -0.37
BXD81 m 0.00130542 7.638e-05   3 4.41e-05 0.0585 0.00126012, 0.00139361 -0.58
BXD84 m 0.00096885 0.00012777   4 6.389e-05 0.1319 0.00083988, 0.0011194 -0.7
BXD87 m 0.00174472 0.00081949   4 0.00040975 0.4697 0.00081244, 0.00276742 -0.44
BXD89 m 0.00264674 0.00115205   5 0.00051521 0.4353 0.00140483, 0.0042666 -0.13
BXD90 m 0.00122145 0.0   1   0.0 0.0 0.00122145, 0.00122145 -0.61
C57BL/6J m 0.00165783 0.00047729   4 0.00023864 0.2879 0.00110119, 0.00225598 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.0056001 0.0009222772 0.0074320903 0.0037681097
BXD12 m 0.003179755 0.0010311372 0.0052279825 0.0011315275
BXD27 m 0.00121975 0.0014582483 0.0041163811 -0.0016768811
BXD32 m 0.0032102775 0.0010311372 0.005258505 0.00116205
BXD34 m 0.00778582 0.0010311372 0.0098340475 0.0057375925
BXD39 m 0.00578203 0.0009222772 0.0076140203 0.0039500397
BXD40 m 0.004913492 0.0009222772 0.0067454823 0.0030815017
BXD43 m 0.000982885 0.0014582483 0.0038795161 -0.0019137461
BXD45 m 0.004387192 0.0009222772 0.0062191823 0.0025552017
BXD48 m 0.002007645 0.0010311372 0.0040558725 -4.05825e-05
BXD48a m 0.00222228 0.0009222772 0.0040542703 0.0003902897
BXD49 m 0.0025208775 0.0010311372 0.004569105 0.00047265
BXD53 m 0.001180664 0.0009222772 0.0030126543 -0.0006513263
BXD55 m 0.003332706 0.0009222772 0.0051646963 0.0015007157
BXD6 m 0.003122994 0.0009222772 0.0049549843 0.0012910037
BXD62 m 0.001356665 0.0010311372 0.0034048925 -0.0006915625
BXD63 m 0.0012813275 0.0010311372 0.003329555 -0.0007669
BXD64 m 0.0024693333 0.0011906547 0.0048344227 0.000104244
BXD67 m 0.001543824 0.0009222772 0.0033758143 -0.0002881663
BXD69 m 0.0013319575 0.0010311372 0.003380185 -0.00071627
BXD73 m 0.0026370375 0.0010311372 0.004685265 0.00058881
BXD75 m 0.00127387 0.0010311372 0.0033220975 -0.0007743575
BXD77 m 0.0048204 0.0010311372 0.0068686275 0.0027721725
BXD79 m 0.001102425 0.0014582483 0.0039990561 -0.0017942061
BXD8 m 0.00193489 0.0011906547 0.0042999794 -0.0004301994
BXD81 m 0.00130542 0.0011906547 0.0036705094 -0.0010596694
BXD84 m 0.00096885 0.0010311372 0.0030170775 -0.0010793775
BXD87 m 0.00174472 0.0010311372 0.0037929475 -0.0003035075
BXD89 m 0.002646744 0.0009222772 0.0044787343 0.0008147537
C57BL/6J m 0.001657835 0.0010311372 0.0037060625 -0.0003903925




  GWAS USING LINEAR MIXED MODELS