Project measure / variable:   Schoonjans1   GCA_liver_HFD

ID, description, units MPD:112823   GCA_liver_HFD   bile acid glycocholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid glycocholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.04557   ng/mL
Median of the strain means0.03401   ng/mL
SD of the strain means± 0.03684
Coefficient of variation (CV)0.8085
Min–max range of strain means0.00981273   –   0.17999   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.2297 0.0066 7.9349 < 0.0001
Residuals 141 0.1166 0.0008


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.17999 0.0784   5 0.03506 0.4356 0.11874, 0.30408 3.65
BXD100 m 0.01038 0.00242466   7 0.00091644 0.2337 0.00679074, 0.01352 -0.96
BXD11 m 0.01731 0.01552   3 0.00896171 0.8968 0.00808708, 0.03523 -0.77
BXD12 m 0.03308 0.02264   4 0.01132 0.6842 0.01423, 0.06189 -0.34
BXD27 m 0.01751 0.01708   5 0.00763754 0.9751 0.00878698, 0.04798 -0.76
BXD32 m 0.06193 0.02069   4 0.01034 0.3341 0.04255, 0.08747 0.44
BXD34 m 0.14578 0.07098   4 0.03549 0.4869 0.07021, 0.239 2.72
BXD39 m 0.0911 0.06464   5 0.02891 0.7095 0.02184, 0.18394 1.24
BXD40 m 0.05126 0.02418   5 0.01081 0.4717 0.0212, 0.08307 0.15
BXD43 m 0.02267 0.00922083   5 0.00412368 0.4067 0.01045, 0.03213 -0.62
BXD45 m 0.02515 0.00644327   5 0.00288152 0.2562 0.01661, 0.03081 -0.55
BXD48 m 0.03087 0.01808   5 0.00808353 0.5855 0.00959939, 0.05912 -0.4
BXD48a m 0.03508 0.00999187   5 0.0044685 0.2848 0.02265, 0.04838 -0.28
BXD49 m 0.06126 0.02542   5 0.01137 0.415 0.02973, 0.0809 0.43
BXD51 m 0.01305 0.00110844   5 0.00049571 0.0849 0.01184, 0.01466 -0.88
BXD53 m 0.06716 0.0221   5 0.00988281 0.3291 0.03465, 0.09667 0.59
BXD55 m 0.03262 0.01664   5 0.00744319 0.5102 0.01689, 0.05125 -0.35
BXD6 m 0.05107 0.01173   5 0.00524396 0.2296 0.0373, 0.06361 0.15
BXD62 m 0.0223 0.01279   5 0.00571917 0.5736 0.01119, 0.04221 -0.63
BXD63 m 0.0281 0.01722   5 0.00770321 0.613 0.00915996, 0.0562 -0.47
BXD64 m 0.05003 0.04949   5 0.02213 0.9893 0.01766, 0.13655 0.12
BXD66 m 0.00991871 0.00150837   9 0.00050279 0.1521 0.00797525, 0.01188 -0.97
BXD67 m 0.02797 0.00913099   5 0.0040835 0.3264 0.01575, 0.03942 -0.48
BXD69 m 0.05258 0.03396   5 0.01519 0.6458 0.02165, 0.10879 0.19
BXD73 m 0.03494 0.00918325   5 0.00410687 0.2628 0.02394, 0.0445 -0.29
BXD75 m 0.06672 0.03162   4 0.01581 0.4739 0.02643, 0.0969 0.57
BXD77 m 0.04793 0.03238   5 0.01448 0.6757 0.00811573, 0.0783 0.06
BXD79 m 0.01324 0.00502565   5 0.00224754 0.3796 0.00927941, 0.02173 -0.88
BXD8 m 0.03173 0.01603   4 0.00801646 0.5053 0.0135, 0.05194 -0.38
BXD81 m 0.05331 0.01701   5 0.00760723 0.3191 0.03538, 0.07198 0.21
BXD84 m 0.05007 0.02627   5 0.01175 0.5247 0.01221, 0.08391 0.12
BXD87 m 0.05565 0.05311   5 0.02375 0.9543 0.01828, 0.14561 0.27
BXD89 m 0.02437 0.00434053   5 0.00194114 0.1781 0.02026, 0.03119 -0.58
BXD90 m 0.01072 0.0016152   3 0.00093254 0.1506 0.00885965, 0.01172 -0.95
C57BL/6J m 0.10376 0.0342   5 0.01529 0.3296 0.05028, 0.13737 1.58
DBA/2J m 0.00981273 0.00141467   5 0.00063266 0.1442 0.00829534, 0.01193 -0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.179986 0.0128627908 0.2054148561 0.1545571439
BXD100 m 0.0103757771 0.0108710423 0.0318670831 -0.0111155288
BXD11 m 0.0173091167 0.0166057915 0.0501376287 -0.0155193954
BXD12 m 0.0330825 0.0143810373 0.0615128254 0.0046521746
BXD27 m 0.01751375 0.0128627908 0.0429426061 -0.0079151061
BXD32 m 0.0619325 0.0143810373 0.0903628254 0.0335021746
BXD34 m 0.145785 0.0143810373 0.1742153254 0.1173546746
BXD39 m 0.091102 0.0128627908 0.1165308561 0.0656731439
BXD40 m 0.051258 0.0128627908 0.0766868561 0.0258291439
BXD43 m 0.022674 0.0128627908 0.0481028561 -0.0027548561
BXD45 m 0.025154 0.0128627908 0.0505828561 -0.0002748561
BXD48 m 0.030871878 0.0128627908 0.0563007341 0.0054430219
BXD48a m 0.035078 0.0128627908 0.0605068561 0.0096491439
BXD49 m 0.061256 0.0128627908 0.0866848561 0.0358271439
BXD51 m 0.01305 0.0128627908 0.0384788561 -0.0123788561
BXD53 m 0.067156 0.0128627908 0.0925848561 0.0417271439
BXD55 m 0.032622 0.0128627908 0.0580508561 0.0071931439
BXD6 m 0.051072 0.0128627908 0.0765008561 0.0256431439
BXD62 m 0.022296 0.0128627908 0.0477248561 -0.0031328561
BXD63 m 0.028097992 0.0128627908 0.0535268481 0.0026691359
BXD64 m 0.050026 0.0128627908 0.0754548561 0.0245971439
BXD66 m 0.00991871 0.0095873582 0.0288722603 -0.0090348403
BXD67 m 0.027972 0.0128627908 0.0534008561 0.0025431439
BXD69 m 0.052584 0.0128627908 0.0780128561 0.0271551439
BXD73 m 0.03494 0.0128627908 0.0603688561 0.0095111439
BXD75 m 0.06672 0.0143810373 0.0951503254 0.0382896746
BXD77 m 0.047927146 0.0128627908 0.0733560021 0.0224982899
BXD79 m 0.01324022 0.0128627908 0.0386690761 -0.0121886361
BXD8 m 0.03173 0.0143810373 0.0601603254 0.0032996746
BXD81 m 0.053312 0.0128627908 0.0787408561 0.0278831439
BXD84 m 0.05007 0.0128627908 0.0754988561 0.0246411439
BXD87 m 0.055652 0.0128627908 0.0810808561 0.0302231439
BXD89 m 0.024372 0.0128627908 0.0498008561 -0.0010568561
BXD90 m 0.0107232167 0.0166057915 0.0435517287 -0.0221052954
C57BL/6J m 0.103758 0.0128627908 0.1291868561 0.0783291439
DBA/2J m 0.009812732 0.0128627908 0.0352415881 -0.0156161241




  GWAS USING LINEAR MIXED MODELS