Project measure / variable:   Schoonjans1   GCA_liver_CD

ID, description, units MPD:112822   GCA_liver_CD   bile acid glycocholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid glycocholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.03927   ng/mL
Median of the strain means0.03333   ng/mL
SD of the strain means± 0.02452
Coefficient of variation (CV)0.6243
Min–max range of strain means0.01281   –   0.13185   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.1032 0.0029 4.11 < 0.0001
Residuals 134 0.0962 0.0007


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.04864 0.02002   4 0.01001 0.4115 0.02659, 0.0752 0.38
BXD100 m 0.03868 0.02789   6 0.01138 0.721 0.01498, 0.08524 -0.02
BXD11 m 0.01821 0.00417726   4 0.00208863 0.2294 0.01328, 0.02335 -0.86
BXD12 m 0.03432 0.01496   4 0.00747788 0.4358 0.01835, 0.05227 -0.2
BXD27 m 0.0676 0.02007   4 0.01004 0.2969 0.05093, 0.09679 1.16
BXD32 m 0.0489 0.02273   5 0.01016 0.4648 0.02022, 0.07386 0.39
BXD34 m 0.05302 0.00895004   5 0.00400258 0.1688 0.04227, 0.06046 0.56
BXD39 m 0.01431 0.00325093   5 0.00145386 0.2272 0.0107, 0.01898 -1.02
BXD40 m 0.04031 0.01842   5 0.00823721 0.4569 0.01159, 0.05911 0.04
BXD43 m 0.03234 0.0285   3 0.01645 0.8812 0.01115, 0.06474 -0.28
BXD45 m 0.01736 0.0041965   4 0.00209825 0.2417 0.01384, 0.02341 -0.89
BXD48 m 0.06048 0.05969   5 0.0267 0.9871 0.02932, 0.16699 0.86
BXD48a m 0.01973 0.00780791   4 0.00390396 0.3957 0.01099, 0.02741 -0.8
BXD49 m 0.05332 0.02184   4 0.01092 0.4096 0.035, 0.08228 0.57
BXD51 m 0.02704 0.0072637   5 0.00324842 0.2686 0.01673, 0.03685 -0.5
BXD53 m 0.04096 0.04477   5 0.02002 1.093 0.01543, 0.12052 0.07
BXD55 m 0.0306 0.00916548   5 0.00409893 0.2995 0.02277, 0.04514 -0.35
BXD6 m 0.02096 0.0077813   5 0.0034799 0.3712 0.01335, 0.03337 -0.75
BXD62 m 0.02 0.00784698   5 0.00350928 0.3924 0.01434, 0.03348 -0.79
BXD63 m 0.02488 0.01026   5 0.00458872 0.4123 0.01352, 0.04135 -0.59
BXD64 m 0.0272 0.008805   3 0.00508357 0.3237 0.02061, 0.0372 -0.49
BXD66 m 0.01281 0.00285821   7 0.0010803 0.2232 0.00960301, 0.01796 -1.08
BXD67 m 0.02626 0.01168   4 0.00584097 0.4449 0.01713, 0.04283 -0.53
BXD69 m 0.04989 0.02403   5 0.01075 0.4817 0.01842, 0.07706 0.43
BXD73 m 0.05529 0.0205   5 0.00916601 0.3707 0.03617, 0.08683 0.65
BXD75 m 0.04122 0.0124   5 0.00554742 0.3009 0.02693, 0.05853 0.08
BXD77 m 0.0496 0.02035   5 0.00910144 0.4103 0.03014, 0.07719 0.42
BXD79 m 0.13185 0.10832   5 0.04844 0.8216 0.02183, 0.27569 3.78
BXD8 m 0.03032 0.00605963   5 0.00270995 0.1998 0.02396, 0.03873 -0.37
BXD81 m 0.02009 0.00537708   4 0.00268854 0.2676 0.01204, 0.02321 -0.78
BXD84 m 0.02053 0.00332834   5 0.00148848 0.1621 0.01587, 0.02399 -0.76
BXD87 m 0.10054 0.01407   5 0.00629223 0.1399 0.07792, 0.11026 2.5
BXD89 m 0.0416 0.01524   5 0.00681421 0.3662 0.02136, 0.06404 0.09
BXD90 m 0.01456 0.00474706   5 0.00212295 0.326 0.0083284, 0.01962 -1.01
C57BL/6J m 0.06068 0.02095   5 0.00936785 0.3452 0.02633, 0.08122 0.87
DBA/2J m 0.01974 0.01311   5 0.00586121 0.6638 0.01038, 0.04124 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.0486425 0.0133946716 0.0751348265 0.0221501735
BXD100 m 0.038675 0.0109367035 0.060305894 0.017044106
BXD11 m 0.01821 0.0133946716 0.0447023265 -0.0082823265
BXD12 m 0.0343175 0.0133946716 0.0608098265 0.0078251735
BXD27 m 0.0676 0.0133946716 0.0940923265 0.0411076735
BXD32 m 0.048898 0.0119805585 0.0725934571 0.0252025429
BXD34 m 0.053024 0.0119805585 0.0767194571 0.0293285429
BXD39 m 0.014308 0.0119805585 0.0380034571 -0.0093874571
BXD40 m 0.040312 0.0119805585 0.0640074571 0.0166165429
BXD43 m 0.03234 0.0154668345 0.0629307036 0.0017492964
BXD45 m 0.01736 0.0133946716 0.0438523265 -0.0091323265
BXD48 m 0.060476 0.0119805585 0.0841714571 0.0367805429
BXD48a m 0.0197325 0.0133946716 0.0462248265 -0.0067598265
BXD49 m 0.0533175 0.0133946716 0.0798098265 0.0268251735
BXD51 m 0.027042 0.0119805585 0.0507374571 0.0033465429
BXD53 m 0.040962 0.0119805585 0.0646574571 0.0172665429
BXD55 m 0.030604 0.0119805585 0.0542994571 0.0069085429
BXD6 m 0.02096 0.0119805585 0.0446554571 -0.0027354571
BXD62 m 0.019996 0.0119805585 0.0436914571 -0.0036994571
BXD63 m 0.024884 0.0119805585 0.0485794571 0.0011885429
BXD64 m 0.0272 0.0154668345 0.0577907036 -0.0033907036
BXD66 m 0.0128061443 0.01012542 0.0328324607 -0.0072201721
BXD67 m 0.02626 0.0133946716 0.0527523265 -0.0002323265
BXD69 m 0.049888 0.0119805585 0.0735834571 0.0261925429
BXD73 m 0.05529 0.0119805585 0.0789854571 0.0315945429
BXD75 m 0.041218 0.0119805585 0.0649134571 0.0175225429
BXD77 m 0.049596 0.0119805585 0.0732914571 0.0259005429
BXD79 m 0.13185 0.0119805585 0.1555454571 0.1081545429
BXD8 m 0.030324 0.0119805585 0.0540194571 0.0066285429
BXD81 m 0.0200925 0.0133946716 0.0465848265 -0.0063998265
BXD84 m 0.020534 0.0119805585 0.0442294571 -0.0031614571
BXD87 m 0.100538 0.0119805585 0.1242334571 0.0768425429
BXD89 m 0.041604 0.0119805585 0.0652994571 0.0179085429
BXD90 m 0.01456368 0.0119805585 0.0382591371 -0.0091317771
C57BL/6J m 0.060678 0.0119805585 0.0843734571 0.0369825429
DBA/2J m 0.019744 0.0119805585 0.0434394571 -0.0039514571




  GWAS USING LINEAR MIXED MODELS