Project measure / variable:   Schoonjans1   bMCA_liver_CD

ID, description, units MPD:112814   bMCA_liver_CD   bile acid β-muricholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid β-muricholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.09709   ng/mL
Median of the strain means0.07184   ng/mL
SD of the strain means± 0.06816
Coefficient of variation (CV)0.702
Min–max range of strain means0.02144   –   0.35387   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.6997 0.02 2.4728 0.0001
Residuals 134 1.0834 0.0081


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.05691 0.0134   4 0.00669895 0.2354 0.04546, 0.07622 -0.59
BXD100 m 0.03235 0.01248   6 0.00509456 0.3858 0.01443, 0.04572 -0.95
BXD11 m 0.0656 0.03614   4 0.01807 0.5509 0.02392, 0.10789 -0.46
BXD12 m 0.1889 0.1672   4 0.0836 0.8851 0.04218, 0.40688 1.35
BXD27 m 0.13709 0.06128   4 0.03064 0.447 0.07128, 0.20268 0.59
BXD32 m 0.1028 0.08696   5 0.03889 0.8459 0.02215, 0.24818 0.08
BXD34 m 0.0621 0.01799   5 0.00804557 0.2897 0.04533, 0.09231 -0.51
BXD39 m 0.07158 0.02763   5 0.01236 0.386 0.04578, 0.11176 -0.37
BXD40 m 0.05875 0.03291   5 0.01472 0.5602 0.01651, 0.1021 -0.56
BXD43 m 0.35387 0.48726   3 0.28132 1.3769 0.0605, 0.91634 3.77
BXD45 m 0.04104 0.01293   4 0.00646495 0.3151 0.02525, 0.05254 -0.82
BXD48 m 0.05686 0.04272   5 0.0191 0.7513 0.02571, 0.12979 -0.59
BXD48a m 0.03052 0.01308   4 0.00654052 0.4287 0.01521, 0.04662 -0.98
BXD49 m 0.02144 0.00597419   4 0.00298709 0.2787 0.01341, 0.02773 -1.11
BXD51 m 0.08166 0.046   5 0.02057 0.5633 0.04602, 0.14984 -0.23
BXD53 m 0.11117 0.09548   5 0.0427 0.8588 0.04775, 0.27841 0.21
BXD55 m 0.049 0.01952   5 0.00872751 0.3983 0.02062, 0.07046 -0.71
BXD6 m 0.13205 0.05054   5 0.0226 0.3827 0.08952, 0.21729 0.51
BXD62 m 0.06563 0.02796   5 0.0125 0.426 0.03634, 0.10514 -0.46
BXD63 m 0.0625 0.03189   5 0.01426 0.5103 0.0206, 0.10599 -0.51
BXD64 m 0.09507 0.0469   3 0.02708 0.4933 0.05045, 0.14395 -0.03
BXD66 m 0.24438 0.15997   7 0.06046 0.6546 0.09733, 0.57032 2.16
BXD67 m 0.1232 0.1036   4 0.0518 0.8409 0.04085, 0.27055 0.38
BXD69 m 0.06125 0.04431   5 0.01982 0.7235 0.02628, 0.13837 -0.53
BXD73 m 0.0721 0.03833   5 0.01714 0.5316 0.03742, 0.12612 -0.37
BXD75 m 0.02402 0.00563179   5 0.00251861 0.2345 0.0195, 0.03373 -1.07
BXD77 m 0.07489 0.0277   5 0.01239 0.3699 0.05219, 0.12004 -0.33
BXD79 m 0.15086 0.06685   5 0.0299 0.4431 0.04173, 0.21056 0.79
BXD8 m 0.10222 0.03933   5 0.01759 0.3848 0.06425, 0.16125 0.08
BXD81 m 0.04905 0.01182   4 0.00590914 0.2409 0.03236, 0.05867 -0.7
BXD84 m 0.19258 0.12713   5 0.05686 0.6602 0.08445, 0.40625 1.4
BXD87 m 0.1687 0.1279   5 0.0572 0.7581 0.06078, 0.33049 1.05
BXD89 m 0.13902 0.05666   5 0.02534 0.4075 0.09692, 0.22846 0.62
BXD90 m 0.1089 0.04019   5 0.01798 0.3691 0.05834, 0.14992 0.17
C57BL/6J m 0.04573 0.02967   5 0.01327 0.6489 0.02888, 0.09865 -0.75
DBA/2J m 0.06149 0.05595   5 0.02502 0.9099 0.01989, 0.15663 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.0569075 0.0449584801 0.1458275399 -0.0320125399
BXD100 m 0.03235 0.0367084453 0.1049529086 -0.0402529086
BXD11 m 0.0656025 0.0449584801 0.1545225399 -0.0233175399
BXD12 m 0.1889 0.0449584801 0.2778200399 0.0999799601
BXD27 m 0.137085 0.0449584801 0.2260050399 0.0481649601
BXD32 m 0.102796 0.040212087 0.1823285015 0.0232634985
BXD34 m 0.062102 0.040212087 0.1416345015 -0.0174305015
BXD39 m 0.071578 0.040212087 0.1511105015 -0.0079545015
BXD40 m 0.058746 0.040212087 0.1382785015 -0.0207865015
BXD43 m 0.3538733333 0.0519135811 0.4565493513 0.2511973153
BXD45 m 0.041035 0.0449584801 0.1299550399 -0.0478850399
BXD48 m 0.056858 0.040212087 0.1363905015 -0.0226745015
BXD48a m 0.030515 0.0449584801 0.1194350399 -0.0584050399
BXD49 m 0.0214375 0.0449584801 0.1103575399 -0.0674825399
BXD51 m 0.081662 0.040212087 0.1611945015 0.0021294985
BXD53 m 0.111174 0.040212087 0.1907065015 0.0316414985
BXD55 m 0.048998 0.040212087 0.1285305015 -0.0305345015
BXD6 m 0.132046 0.040212087 0.2115785015 0.0525134985
BXD62 m 0.065632 0.040212087 0.1451645015 -0.0139005015
BXD63 m 0.062498 0.040212087 0.1420305015 -0.0170345015
BXD64 m 0.09507 0.0519135811 0.197746018 -0.007606018
BXD66 m 0.24438 0.0339854165 0.3115972321 0.1771627679
BXD67 m 0.1231975 0.0449584801 0.2121175399 0.0342774601
BXD69 m 0.061252 0.040212087 0.1407845015 -0.0182805015
BXD73 m 0.072098 0.040212087 0.1516305015 -0.0074345015
BXD75 m 0.024016 0.040212087 0.1035485015 -0.0555165015
BXD77 m 0.074888 0.040212087 0.1544205015 -0.0046445015
BXD79 m 0.150864 0.040212087 0.2303965015 0.0713314985
BXD8 m 0.102224 0.040212087 0.1817565015 0.0226914985
BXD81 m 0.049055 0.0449584801 0.1379750399 -0.0398650399
BXD84 m 0.19258 0.040212087 0.2721125015 0.1130474985
BXD87 m 0.1687 0.040212087 0.2482325015 0.0891674985
BXD89 m 0.13902 0.040212087 0.2185525015 0.0594874985
BXD90 m 0.1089 0.040212087 0.1884325015 0.0293674985
C57BL/6J m 0.04573 0.040212087 0.1252625015 -0.0338025015
DBA/2J m 0.061494 0.040212087 0.1410265015 -0.0180385015




  GWAS USING LINEAR MIXED MODELS