Project measure / variable:   Schoonjans1   keto_DCA_liver_HFD

ID, description, units MPD:112810   keto_DCA_liver_HFD   bile acid 7-ketodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   8 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid 7-ketodeoxycholic acid amount in liver, at 29 wks HFD

BXD49BXD12BXD32BXD89BXD1BXD45BXD11BXD73 ng/mL 0.010.020.030.040.050.060.070.080.090.10femalemale


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means0.02087   ng/mL
Median of the strain means0.01432   ng/mL
SD of the strain means± 0.01168
Coefficient of variation (CV)0.5595
Min–max range of strain means0.00989879   –   0.04082   ng/mL
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 3 0.0014 0.0005 0.623 0.6223
Residuals 7 0.0052 0.0007


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
BXD1 m 0.01425 0.0   1   0.0 0.0 0.01425, 0.01425 -0.57
BXD11 m 0.01322 0.0   1   0.0 0.0 0.01322, 0.01322 -0.66
BXD12 m 0.03592 0.02028   2   0.01434 0.5646 0.02158, 0.05026 1.29
BXD32 m 0.02469 0.01584   2   0.0112 0.6415 0.01349, 0.03589 0.33
BXD45 m 0.01377 0.00245636   3 0.00141818 0.1784 0.01106, 0.01585 -0.61
BXD49 m 0.04082 0.03876   4 0.01938 0.9495 0.01309, 0.09619 1.71
BXD73 m 0.00989879 0.0   1   0.0 0.0 0.00989879, 0.00989879 -0.94
BXD89 m 0.01438 0.0   1   0.0 0.0 0.01438, 0.01438 -0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD12 m 0.03592 0.0192388099 0.0814125564 -0.0095725564
BXD32 m 0.02469 0.0192388099 0.0701825564 -0.0208025564
BXD45 m 0.01377 0.0157084225 0.0509145168 -0.0233745168
BXD49 m 0.0408225 0.0136038929 0.0729905951 0.0086544049




  GWAS USING LINEAR MIXED MODELS

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