Project measure / variable:   Schoonjans1   keto_DCA_liver_CD

ID, description, units MPD:112809   keto_DCA_liver_CD   bile acid 7-ketodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   7 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid 7-ketodeoxycholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means0.03162   ng/mL
Median of the strain means0.03163   ng/mL
SD of the strain means± 0.01294
Coefficient of variation (CV)0.4092
Min–max range of strain means0.01012   –   0.04695   ng/mL
Mean sample size per strain1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 3 0.0014 0.0005 2.3341 0.2154
Residuals 4 0.0008 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD12 m 0.03163 0.01717   2   0.01214 0.5428 0.01949, 0.04377 0.0
BXD32 m 0.04196 0.0   1   0.0 0.0 0.04196, 0.04196 0.8
BXD43 m 0.04108 0.0   1   0.0 0.0 0.04108, 0.04108 0.73
BXD48 m 0.02181 0.0   1   0.0 0.0 0.02181, 0.02181 -0.76
BXD6 m 0.04695 0.01132   2   0.008005 0.2411 0.03895, 0.05496 1.18
BXD87 m 0.02779 0.01901   2   0.01344 0.684 0.01435, 0.04123 -0.3
BXD89 m 0.01012 0.00097865   2   0.00069201 0.0967 0.00942598, 0.01081 -1.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD12 m 0.03163 0.0099067162 0.0591354537 0.0041245463
BXD6 m 0.046955 0.0099067162 0.0744604537 0.0194495463
BXD87 m 0.02779 0.0099067162 0.0552954537 0.0002845463
BXD89 m 0.01011799 0.0099067162 0.0376234437 -0.0173874637




  GWAS USING LINEAR MIXED MODELS