Project measure / variable:   Schoonjans1   wMCA_feces_HFD

ID, description, units MPD:112807   wMCA_feces_HFD   bile acid ω-muricholic acid in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid ω-muricholic acid in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means48.608   ng/mL
Median of the strain means45.397   ng/mL
SD of the strain means± 17.836
Coefficient of variation (CV)0.3669
Min–max range of strain means17.566   –   84.59   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 52668.1748 1504.805 6.7073 < 0.0001
Residuals 136 30512.1034 224.3537


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 49.228 6.6219   5 2.9614 0.1345 41.534, 57.24 0.03
BXD100 m 22.017 9.5605   4 4.7802 0.4342 11.755, 34.449 -1.49
BXD11 m 48.404 36.943   3 21.329 0.7632 19.22, 89.94 -0.01
BXD12 m 25.414 15.586   4 7.7928 0.6133 8.6262, 40.219 -1.3
BXD27 m 33.484 14.035   6 5.7296 0.4191 16.276, 58.31 -0.85
BXD32 m 28.604 8.4919   4 4.2459 0.2969 20.593, 39.059 -1.12
BXD34 m 77.73 11.263   4 5.6314 0.1449 65.34, 92.28 1.63
BXD39 m 41.512 11.161   5 4.9915 0.2689 31.184, 54.8 -0.4
BXD40 m 56.09 21.56   5 9.6419 0.3844 28.314, 88.23 0.42
BXD43 m 52.37 16.654   5 7.4481 0.318 36.235, 77.59 0.21
BXD45 m 43.709 11.114   5 4.9704 0.2543 27.982, 58.21 -0.27
BXD48 m 80.94 12.639   5 5.6521 0.1561 67.97, 96.93 1.81
BXD48a m 38.883 11.208   5 5.0124 0.2882 24.273, 55.36 -0.55
BXD49 m 35.803 13.407   5 5.996 0.3745 23.83, 56.08 -0.72
BXD51 m 53.83 12.345   5 5.5207 0.2293 37.314, 70.94 0.29
BXD53 m 33.851 18.221   5 8.1486 0.5383 2.9669, 48.476 -0.83
BXD55 m 40.384 5.6417   5 2.5231 0.1397 33.95, 49.238 -0.46
BXD6 m 17.566 4.8292   5 2.1597 0.2749 11.547, 21.664 -1.74
BXD62 m 32.77 8.3382   5 3.7289 0.2544 24.798, 43.484 -0.89
BXD63 m 35.091 23.204   5 10.377 0.6612 14.979, 74.03 -0.76
BXD64 m 44.74 9.8956   5 4.4254 0.2212 35.843, 59.76 -0.22
BXD66 m 75.83 13.681   5 6.1185 0.1804 62.07, 91.9 1.53
BXD67 m 53.71 12.441   5 5.5638 0.2316 39.929, 66.1 0.29
BXD69 m 46.053 8.891   5 3.9762 0.1931 34.73, 57.21 -0.14
BXD73 m 34.238 22.23   5 9.9414 0.6493 16.168, 70.66 -0.81
BXD75 m 73.69 19.775   5 8.8435 0.2683 44.956, 95.01 1.41
BXD77 m 84.59 23.771   5 10.631 0.281 51.0, 113.4 2.02
BXD79 m 54.98 20.397   5 9.1217 0.371 20.772, 71.83 0.36
BXD8 m 30.379 8.1191   4 4.0596 0.2673 22.459, 38.976 -1.02
BXD81 m 42.976 6.1847   5 2.7659 0.1439 36.594, 51.23 -0.32
BXD84 m 62.96 19.104   3 11.03 0.3035 44.716, 82.82 0.8
BXD87 m 57.18 5.4518   5 2.4381 0.0953 52.18, 63.29 0.48
BXD89 m 78.22 14.419   5 6.4483 0.1843 58.89, 92.94 1.66
BXD90 m 67.91 22.665   5 10.136 0.3337 41.301, 100.8 1.08
C57BL/6J m 61.49 9.1194   5 4.0783 0.1483 51.51, 75.03 0.72
DBA/2J m 33.255 12.762   5 5.7072 0.3837 16.845, 51.47 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 49.2282 6.6985625517 62.4750145615 35.9813854385
BXD100 m 22.0165 7.4892206085 36.8268889224 7.2061110776
BXD11 m 48.4036666667 8.6478070687 65.505230729 31.3021026043
BXD12 m 25.41355 7.4892206085 40.2239389224 10.6031610776
BXD27 m 33.4836666667 6.1149230207 45.5762985841 21.3910347493
BXD32 m 28.60375 7.4892206085 43.4141389224 13.7933610776
BXD34 m 77.73 7.4892206085 92.5403889224 62.9196110776
BXD39 m 41.5116 6.6985625517 54.7584145615 28.2647854385
BXD40 m 56.092 6.6985625517 69.3388145615 42.8451854385
BXD43 m 52.3748 6.6985625517 65.6216145615 39.1279854385
BXD45 m 43.709 6.6985625517 56.9558145615 30.4621854385
BXD48 m 80.944 6.6985625517 94.1908145615 67.6971854385
BXD48a m 38.8834 6.6985625517 52.1302145615 25.6365854385
BXD49 m 35.803 6.6985625517 49.0498145615 22.5561854385
BXD51 m 53.8274 6.6985625517 67.0742145615 40.5805854385
BXD53 m 33.85058 6.6985625517 47.0973945615 20.6037654385
BXD55 m 40.3838 6.6985625517 53.6306145615 27.1369854385
BXD6 m 17.5662 6.6985625517 30.8130145615 4.3193854385
BXD62 m 32.7698 6.6985625517 46.0166145615 19.5229854385
BXD63 m 35.0914 6.6985625517 48.3382145615 21.8445854385
BXD64 m 44.7404 6.6985625517 57.9872145615 31.4935854385
BXD66 m 75.834 6.6985625517 89.0808145615 62.5871854385
BXD67 m 53.7112 6.6985625517 66.9580145615 40.4643854385
BXD69 m 46.0528 6.6985625517 59.2996145615 32.8059854385
BXD73 m 34.2382 6.6985625517 47.4850145615 20.9913854385
BXD75 m 73.6932 6.6985625517 86.9400145615 60.4463854385
BXD77 m 84.594 6.6985625517 97.8408145615 71.3471854385
BXD79 m 54.9784 6.6985625517 68.2252145615 41.7315854385
BXD8 m 30.37875 7.4892206085 45.1891389224 15.5683610776
BXD81 m 42.9762 6.6985625517 56.2230145615 29.7293854385
BXD84 m 62.9553333333 8.6478070687 80.0568973957 45.853769271
BXD87 m 57.18 6.6985625517 70.4268145615 43.9331854385
BXD89 m 78.22 6.6985625517 91.4668145615 64.9731854385
BXD90 m 67.9142 6.6985625517 81.1610145615 54.6673854385
C57BL/6J m 61.486 6.6985625517 74.7328145615 48.2391854385
DBA/2J m 33.2552 6.6985625517 46.5020145615 20.0083854385




  GWAS USING LINEAR MIXED MODELS