Project measure / variable:   Schoonjans1   UDCA_feces_HFD

ID, description, units MPD:112805   UDCA_feces_HFD   bile acid ursodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid ursodeoxycholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.94538   ng/mL
Median of the strain means0.66679   ng/mL
SD of the strain means± 0.78673
Coefficient of variation (CV)0.8322
Min–max range of strain means0.19715   –   3.2515   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 104.0817 2.9738 5.311 < 0.0001
Residuals 135 75.5897 0.5599


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.0976 0.40317   5 0.1803 0.3673 0.68886, 1.559 0.19
BXD100 m 0.29513 0.12923   4 0.06462 0.4379 0.14529, 0.46019 -0.83
BXD11 m 0.36487 0.25812   3 0.14902 0.7074 0.15753, 0.65396 -0.74
BXD12 m 0.32661 0.1904   4 0.0952 0.583 0.10815, 0.56012 -0.79
BXD27 m 1.0442 0.60918   6 0.2487 0.5834 0.38603, 2.1692 0.13
BXD32 m 1.2536 0.69035   4 0.34518 0.5507 0.78256, 2.2697 0.39
BXD34 m 1.8214 0.61482   4 0.30741 0.3376 1.3565, 2.727 1.11
BXD39 m 0.25161 0.10957   5 0.049 0.4355 0.12227, 0.38927 -0.88
BXD40 m 0.38092 0.2342   5 0.10474 0.6148 0.15325, 0.746 -0.72
BXD43 m 0.54173 0.11196   5 0.05007 0.2067 0.36908, 0.65314 -0.51
BXD45 m 1.3077 0.77896   5 0.34836 0.5957 0.55344, 2.4953 0.46
BXD48 m 3.0293 1.7462   5 0.7809 0.5764 1.0216, 4.9971 2.65
BXD48a m 1.1442 0.6751   5 0.30192 0.59 0.43505, 2.1343 0.25
BXD49 m 0.66753 0.28785   5 0.12873 0.4312 0.37526, 1.1082 -0.35
BXD51 m 2.1531 0.72982   5 0.32638 0.339 1.3929, 3.2665 1.54
BXD53 m 0.34641 0.29558   5 0.13219 0.8533 0.02611, 0.80917 -0.76
BXD55 m 0.87438 0.20575   5 0.09202 0.2353 0.59599, 1.1451 -0.09
BXD6 m 0.21633 0.11849   5 0.05299 0.5477 0.09648, 0.37464 -0.93
BXD62 m 0.64474 0.41415   5 0.18521 0.6423 0.18632, 1.1977 -0.38
BXD63 m 0.28536 0.10586   5 0.04734 0.371 0.15871, 0.3997 -0.84
BXD64 m 0.29974 0.09088   5 0.04064 0.3032 0.15008, 0.38808 -0.82
BXD66 m 0.77383 0.38424   5 0.17184 0.4965 0.45068, 1.2696 -0.22
BXD67 m 0.34406 0.17879   5 0.07996 0.5197 0.14521, 0.59756 -0.76
BXD69 m 0.66605 0.36256   5 0.16214 0.5443 0.29275, 1.201 -0.36
BXD73 m 0.60141 0.27533   5 0.12313 0.4578 0.15387, 0.85193 -0.44
BXD75 m 1.9568 1.1886   5 0.53156 0.6074 0.46817, 3.4478 1.29
BXD77 m 2.4406 1.5682   5 0.70134 0.6426 0.57281, 4.0565 1.9
BXD79 m 0.3918 0.20845   5 0.09322 0.532 0.06804, 0.57097 -0.7
BXD8 m 0.19715 0.05103   3 0.02946 0.2588 0.15499, 0.25388 -0.95
BXD81 m 0.51271 0.35917   5 0.16063 0.7005 0.22331, 1.0549 -0.55
BXD84 m 0.35988 0.2734   3 0.15785 0.7597 0.14113, 0.66639 -0.74
BXD87 m 0.84319 0.63699   5 0.28487 0.7555 0.27693, 1.9027 -0.13
BXD89 m 1.3477 0.40856   5 0.18271 0.3032 0.98628, 2.0072 0.51
BXD90 m 1.1338 0.71115   5 0.31804 0.6272 0.70355, 2.3897 0.24
C57BL/6J m 3.2515 2.5424   5 1.137 0.7819 1.176, 6.2526 2.93
DBA/2J m 0.86684 0.63502   5 0.28399 0.7326 0.24075, 1.8565 -0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.0976 0.3346412879 1.7594174907 0.4357825093
BXD100 m 0.2951325 0.3741403339 1.0350669489 -0.4448019489
BXD11 m 0.3648666667 0.432020045 1.2192693732 -0.4895360399
BXD12 m 0.326605 0.3741403339 1.0665394489 -0.4133294489
BXD27 m 1.044215 0.3054843034 1.6483689477 0.4400610523
BXD32 m 1.253585 0.3741403339 1.9935194489 0.5136505511
BXD34 m 1.821425 0.3741403339 2.5613594489 1.0814905511
BXD39 m 0.251612 0.3346412879 0.9134294907 -0.4102054907
BXD40 m 0.380922 0.3346412879 1.0427394907 -0.2808954907
BXD43 m 0.541726 0.3346412879 1.2035434907 -0.1200914907
BXD45 m 1.307712 0.3346412879 1.9695294907 0.6458945093
BXD48 m 3.0293 0.3346412879 3.6911174907 2.3674825093
BXD48a m 1.144204 0.3346412879 1.8060214907 0.4823865093
BXD49 m 0.667532 0.3346412879 1.3293494907 0.0057145093
BXD51 m 2.15308 0.3346412879 2.8148974907 1.4912625093
BXD53 m 0.346406 0.3346412879 1.0082234907 -0.3154114907
BXD55 m 0.874376 0.3346412879 1.5361934907 0.2125585093
BXD6 m 0.216334 0.3346412879 0.8781514907 -0.4454834907
BXD62 m 0.644742 0.3346412879 1.3065594907 -0.0170754907
BXD63 m 0.285358 0.3346412879 0.9471754907 -0.3764594907
BXD64 m 0.299744 0.3346412879 0.9615614907 -0.3620734907
BXD66 m 0.773826 0.3346412879 1.4356434907 0.1120085093
BXD67 m 0.344058 0.3346412879 1.0058754907 -0.3177594907
BXD69 m 0.666054 0.3346412879 1.3278714907 0.0042365093
BXD73 m 0.601414 0.3346412879 1.2632314907 -0.0604034907
BXD75 m 1.956834 0.3346412879 2.6186514907 1.2950165093
BXD77 m 2.440562 0.3346412879 3.1023794907 1.7787445093
BXD79 m 0.391802 0.3346412879 1.0536194907 -0.2700154907
BXD8 m 0.1971533333 0.432020045 1.0515560399 -0.6572493732
BXD81 m 0.512706 0.3346412879 1.1745234907 -0.1491114907
BXD84 m 0.3598833333 0.432020045 1.2142860399 -0.4945193732
BXD87 m 0.843192 0.3346412879 1.5050094907 0.1813745093
BXD89 m 1.347656 0.3346412879 2.0094734907 0.6858385093
BXD90 m 1.133814 0.3346412879 1.7956314907 0.4719965093
C57BL/6J m 3.25148 0.3346412879 3.9132974907 2.5896625093
DBA/2J m 0.866844 0.3346412879 1.5286614907 0.2050265093




  GWAS USING LINEAR MIXED MODELS