Project measure / variable:   Schoonjans1   TUDCA_feces_HFD

ID, description, units MPD:112803   TUDCA_feces_HFD   bile acid tauroursodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauroursodeoxycholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.33172   ng/mL
Median of the strain means0.13726   ng/mL
SD of the strain means± 0.60292
Coefficient of variation (CV)1.8176
Min–max range of strain means0.04276   –   3.2937   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 63.2894 1.8083 4.3902 < 0.0001
Residuals 136 56.0167 0.4119


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.39154 0.34785   5 0.15556 0.8884 0.09737, 0.9592 0.1
BXD100 m 0.41936 0.10641   4 0.0532 0.2537 0.27725, 0.53287 0.15
BXD11 m 0.17805 0.11262   3 0.06502 0.6326 0.05841, 0.28202 -0.25
BXD12 m 0.13756 0.09857   4 0.04928 0.7166 0.07249, 0.28442 -0.32
BXD27 m 0.6088 0.74458   6 0.30397 1.223 0.08604, 2.0701 0.46
BXD32 m 0.12495 0.0467   4 0.02335 0.3738 0.08268, 0.1781 -0.34
BXD34 m 0.12805 0.02245   4 0.01123 0.1753 0.10348, 0.14821 -0.34
BXD39 m 0.11085 0.05856   5 0.02619 0.5283 0.05234, 0.20289 -0.37
BXD40 m 0.09361 0.02871   5 0.01284 0.3067 0.06095, 0.12696 -0.39
BXD43 m 0.13666 0.04628   5 0.0207 0.3387 0.0885, 0.20784 -0.32
BXD45 m 0.13696 0.02733   5 0.01222 0.1995 0.09349, 0.16024 -0.32
BXD48 m 1.9173 1.6343   5 0.73088 0.8524 0.13143, 4.4891 2.63
BXD48a m 0.14105 0.09601   5 0.04294 0.6807 0.04925, 0.28446 -0.32
BXD49 m 0.1366 0.02504   5 0.0112 0.1833 0.10936, 0.15903 -0.32
BXD51 m 3.2937 2.9418   5 1.3156 0.8931 0.45674, 8.251 4.91
BXD53 m 0.09423 0.10281   5 0.04598 1.0911 0.00957035, 0.27266 -0.39
BXD55 m 0.19564 0.02159   5 0.00965319 0.1103 0.15822, 0.20984 -0.23
BXD6 m 0.1 0.07997   5 0.03576 0.7997 0.04375, 0.2271 -0.38
BXD62 m 0.08039 0.01574   5 0.00703991 0.1958 0.06191, 0.09728 -0.42
BXD63 m 0.07502 0.04695   5 0.021 0.6258 0.03699, 0.15601 -0.43
BXD64 m 0.08943 0.02902   5 0.01298 0.3245 0.06152, 0.13392 -0.4
BXD66 m 0.19931 0.07674   5 0.03432 0.385 0.13723, 0.31413 -0.22
BXD67 m 0.05427 0.01168   5 0.00522211 0.2152 0.03999, 0.06439 -0.46
BXD69 m 0.04707 0.01078   5 0.00482001 0.229 0.03497, 0.06438 -0.47
BXD73 m 0.17208 0.07516   5 0.03361 0.4368 0.06966, 0.26943 -0.26
BXD75 m 0.67947 0.7479   5 0.33447 1.1007 0.09291, 1.8841 0.58
BXD77 m 0.29097 0.25056   5 0.11206 0.8611 0.05278, 0.65619 -0.07
BXD79 m 0.13317 0.06423   5 0.02872 0.4823 0.0242, 0.18619 -0.33
BXD8 m 0.13255 0.0354   4 0.0177 0.2671 0.09376, 0.17479 -0.33
BXD81 m 0.36052 0.69881   5 0.31252 1.9384 0.0326, 1.6101 0.05
BXD84 m 0.04276 0.00669516   3 0.00386546 0.1566 0.03506, 0.04718 -0.48
BXD87 m 0.19658 0.13761   5 0.06154 0.7 0.07506, 0.41264 -0.22
BXD89 m 0.14435 0.05819   5 0.02603 0.4032 0.084, 0.23895 -0.31
BXD90 m 0.10666 0.05036   5 0.02252 0.4722 0.05944, 0.19137 -0.37
C57BL/6J m 0.27279 0.30389   5 0.1359 1.114 0.03475, 0.63517 -0.1
DBA/2J m 0.51963 0.74753   5 0.3343 1.4386 0.06544, 1.8486 0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.391536 0.2870148387 0.9591252874 -0.1760532874
BXD100 m 0.419365 0.320892345 1.0539491149 -0.2152191149
BXD11 m 0.1780466667 0.3705345635 0.9108012858 -0.5547079525
BXD12 m 0.13756 0.320892345 0.7721441149 -0.4970241149
BXD27 m 0.6087966667 0.2620075025 1.1269324268 0.0906609065
BXD32 m 0.1249475 0.320892345 0.7595316149 -0.5096366149
BXD34 m 0.1280475 0.320892345 0.7626316149 -0.5065366149
BXD39 m 0.110848 0.2870148387 0.6784372874 -0.4567412874
BXD40 m 0.093612 0.2870148387 0.6612012874 -0.4739772874
BXD43 m 0.136662 0.2870148387 0.7042512874 -0.4309272874
BXD45 m 0.13696 0.2870148387 0.7045492874 -0.4306292874
BXD48 m 1.917326 0.2870148387 2.4849152874 1.3497367126
BXD48a m 0.141048 0.2870148387 0.7086372874 -0.4265412874
BXD49 m 0.1366 0.2870148387 0.7041892874 -0.4309892874
BXD51 m 3.293728 0.2870148387 3.8613172874 2.7261387126
BXD53 m 0.09423207 0.2870148387 0.6618213574 -0.4733572174
BXD55 m 0.195644 0.2870148387 0.7632332874 -0.3719452874
BXD6 m 0.1 0.2870148387 0.6675892874 -0.4675892874
BXD62 m 0.080386 0.2870148387 0.6479752874 -0.4872032874
BXD63 m 0.075018 0.2870148387 0.6426072874 -0.4925712874
BXD64 m 0.089426 0.2870148387 0.6570152874 -0.4781632874
BXD66 m 0.19931 0.2870148387 0.7668992874 -0.3682792874
BXD67 m 0.054272 0.2870148387 0.6218612874 -0.5133172874
BXD69 m 0.047068 0.2870148387 0.6146572874 -0.5205212874
BXD73 m 0.172082 0.2870148387 0.7396712874 -0.3955072874
BXD75 m 0.679474 0.2870148387 1.2470632874 0.1118847126
BXD77 m 0.290968 0.2870148387 0.8585572874 -0.2766212874
BXD79 m 0.133172 0.2870148387 0.7007612874 -0.4344172874
BXD8 m 0.1325525 0.320892345 0.7671366149 -0.5020316149
BXD81 m 0.360516 0.2870148387 0.9281052874 -0.2070732874
BXD84 m 0.0427633333 0.3705345635 0.7755179525 -0.6899912858
BXD87 m 0.19658 0.2870148387 0.7641692874 -0.3710092874
BXD89 m 0.144346 0.2870148387 0.7119352874 -0.4232432874
BXD90 m 0.10666 0.2870148387 0.6742492874 -0.4609292874
C57BL/6J m 0.272794 0.2870148387 0.8403832874 -0.2947952874
DBA/2J m 0.519628 0.2870148387 1.0872172874 -0.0479612874




  GWAS USING LINEAR MIXED MODELS