Project measure / variable:   Schoonjans1   TUDCA_feces_CD

ID, description, units MPD:112802   TUDCA_feces_CD   bile acid tauroursodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauroursodeoxycholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.09274   ng/mL
Median of the strain means0.06784   ng/mL
SD of the strain means± 0.06732
Coefficient of variation (CV)0.7259
Min–max range of strain means0.02986   –   0.39139   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.7848 0.0224 3.8266 < 0.0001
Residuals 139 0.8145 0.0059


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.07067 0.02133   5 0.00954084 0.3019 0.0443, 0.09848 -0.33
BXD100 m 0.16467 0.04031   5 0.01803 0.2448 0.12806, 0.23355 1.07
BXD11 m 0.13679 0.01211   4 0.00605529 0.0885 0.12049, 0.14796 0.65
BXD12 m 0.04163 0.00897098   4 0.00448549 0.2155 0.03508, 0.05417 -0.76
BXD27 m 0.13451 0.06228   4 0.03114 0.463 0.06366, 0.20428 0.62
BXD32 m 0.2056 0.30734   4 0.15367 1.4949 0.04718, 0.66658 1.68
BXD34 m 0.0465 0.02163   4 0.01081 0.4651 0.02286, 0.06677 -0.69
BXD39 m 0.0641 0.02132   5 0.00953312 0.3326 0.03689, 0.0845 -0.43
BXD40 m 0.0373 0.01434   5 0.00641489 0.3845 0.02506, 0.05719 -0.82
BXD43 m 0.06212 0.03888   4 0.01944 0.626 0.03111, 0.11852 -0.45
BXD45 m 0.12017 0.13284   3 0.0767 1.1055 0.02269, 0.27148 0.41
BXD48 m 0.02986 0.00718375   5 0.00321267 0.2406 0.0218, 0.04132 -0.93
BXD48a m 0.12083 0.0267   4 0.01335 0.221 0.09283, 0.1554 0.42
BXD49 m 0.04846 0.01023   5 0.00457456 0.2111 0.03953, 0.06536 -0.66
BXD51 m 0.08117 0.01813   5 0.00810913 0.2234 0.05717, 0.10128 -0.17
BXD53 m 0.04768 0.01348   5 0.006029 0.2828 0.02888, 0.06351 -0.67
BXD55 m 0.05552 0.0151   5 0.00675208 0.2719 0.04029, 0.0769 -0.55
BXD6 m 0.05027 0.01053   5 0.00471003 0.2095 0.03646, 0.06388 -0.63
BXD62 m 0.1075 0.04455   5 0.01992 0.4144 0.06908, 0.18241 0.22
BXD63 m 0.03979 0.02594   5 0.0116 0.6519 0.02595, 0.08589 -0.79
BXD64 m 0.08894 0.01497   5 0.00669621 0.1684 0.07594, 0.11398 -0.06
BXD66 m 0.13362 0.07177   5 0.03209 0.5371 0.06613, 0.24512 0.61
BXD67 m 0.05814 0.01652   4 0.00825887 0.2841 0.03974, 0.07638 -0.51
BXD69 m 0.06146 0.02324   5 0.0104 0.3782 0.03317, 0.08319 -0.46
BXD73 m 0.04643 0.01632   5 0.00729877 0.3515 0.02365, 0.06122 -0.69
BXD75 m 0.08626 0.04612   5 0.02063 0.5346 0.0465, 0.16162 -0.1
BXD77 m 0.06366 0.02658   5 0.01189 0.4176 0.02876, 0.10054 -0.43
BXD79 m 0.11542 0.04771   5 0.02134 0.4134 0.07492, 0.18384 0.34
BXD8 m 0.10606 0.06537   5 0.02923 0.6164 0.05059, 0.19528 0.2
BXD81 m 0.065 0.01667   5 0.00745551 0.2565 0.05015, 0.08544 -0.41
BXD84 m 0.04433 0.01385   5 0.00619256 0.3124 0.02608, 0.05969 -0.72
BXD87 m 0.07525 0.01643   5 0.00734594 0.2183 0.05023, 0.09462 -0.26
BXD89 m 0.14865 0.11971   5 0.05354 0.8053 0.08348, 0.36244 0.83
BXD90 m 0.15683 0.19025   5 0.08508 1.2131 0.05155, 0.49649 0.95
C57BL/6J m 0.03209 0.01742   10 0.00550934 0.5429 0.01391, 0.07007 -0.9
DBA/2J m 0.39139 0.21151   5 0.09459 0.5404 0.1123, 0.60952 4.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.070674 0.0342338454 0.1383603965 0.0029876035
BXD100 m 0.164672 0.0342338454 0.2323583965 0.0969856035
BXD11 m 0.13679 0.0382746027 0.2124656918 0.0611143082
BXD12 m 0.041635 0.0382746027 0.1173106918 -0.0340406918
BXD27 m 0.13451 0.0382746027 0.2101856918 0.0588343082
BXD32 m 0.2056 0.0382746027 0.2812756918 0.1299243082
BXD34 m 0.046505 0.0382746027 0.1221806918 -0.0291706918
BXD39 m 0.064096 0.0342338454 0.1317823965 -0.0035903965
BXD40 m 0.037304 0.0342338454 0.1049903965 -0.0303823965
BXD43 m 0.062115 0.0382746027 0.1377906918 -0.0135606918
BXD45 m 0.12017 0.0441957043 0.2075527621 0.0327872379
BXD48 m 0.02986 0.0342338454 0.0975463965 -0.0378263965
BXD48a m 0.1208275 0.0382746027 0.1965031918 0.0451518082
BXD49 m 0.048464 0.0342338454 0.1161503965 -0.0192223965
BXD51 m 0.08117 0.0342338454 0.1488563965 0.0134836035
BXD53 m 0.047676 0.0342338454 0.1153623965 -0.0200103965
BXD55 m 0.055522 0.0342338454 0.1232083965 -0.0121643965
BXD6 m 0.050266 0.0342338454 0.1179523965 -0.0174203965
BXD62 m 0.107504 0.0342338454 0.1751903965 0.0398176035
BXD63 m 0.039788 0.0342338454 0.1074743965 -0.0278983965
BXD64 m 0.088936 0.0342338454 0.1566223965 0.0212496035
BXD66 m 0.13362 0.0342338454 0.2013063965 0.0659336035
BXD67 m 0.058145 0.0382746027 0.1338206918 -0.0175306918
BXD69 m 0.06146 0.0342338454 0.1291463965 -0.0062263965
BXD73 m 0.046428 0.0342338454 0.1141143965 -0.0212583965
BXD75 m 0.086264 0.0342338454 0.1539503965 0.0185776035
BXD77 m 0.063656 0.0342338454 0.1313423965 -0.0040303965
BXD79 m 0.115418 0.0342338454 0.1831043965 0.0477316035
BXD8 m 0.106058 0.0342338454 0.1737443965 0.0383716035
BXD81 m 0.064998 0.0342338454 0.1326843965 -0.0026883965
BXD84 m 0.044326 0.0342338454 0.1120123965 -0.0233603965
BXD87 m 0.075246 0.0342338454 0.1429323965 0.0075596035
BXD89 m 0.14865 0.0342338454 0.2163363965 0.0809636035
BXD90 m 0.156834 0.0342338454 0.2245203965 0.0891476035
C57BL/6J m 0.032093 0.0242069842 0.0799545099 -0.0157685099
DBA/2J m 0.391394 0.0342338454 0.4590803965 0.3237076035




  GWAS USING LINEAR MIXED MODELS