Project measure / variable:   Schoonjans1   TLCA_feces_HFD

ID, description, units MPD:112801   TLCA_feces_HFD   bile acid taurolithocholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurolithocholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.05285   ng/mL
Median of the strain means0.03683   ng/mL
SD of the strain means± 0.04718
Coefficient of variation (CV)0.8926
Min–max range of strain means0.00861242   –   0.1855   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.3966 0.0113 2.3945 0.0002
Residuals 135 0.6389 0.0047


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.04621 0.0159   5 0.00710927 0.344 0.03027, 0.06899 -0.14
BXD100 m 0.00861242 0.00252057   4 0.00126028 0.2927 0.0055099, 0.01137 -0.94
BXD11 m 0.01646 0.01794   3 0.01036 1.0894 0.0054249, 0.03716 -0.77
BXD12 m 0.03513 0.02138   4 0.01069 0.6087 0.01408, 0.0546 -0.38
BXD27 m 0.1855 0.21008   6 0.08576 1.1325 0.06462, 0.60793 2.81
BXD32 m 0.07414 0.06051   4 0.03026 0.8163 0.03839, 0.16458 0.45
BXD34 m 0.01858 0.01185   4 0.00592255 0.6374 0.01042, 0.03618 -0.73
BXD39 m 0.02437 0.0118   5 0.00527614 0.4842 0.01085, 0.03893 -0.6
BXD40 m 0.01356 0.01139   5 0.0050945 0.8402 0.00571148, 0.03358 -0.83
BXD43 m 0.07098 0.02345   5 0.01049 0.3303 0.03583, 0.09588 0.38
BXD45 m 0.01416 0.00239319   5 0.00107027 0.169 0.01022, 0.01641 -0.82
BXD48 m 0.18073 0.08244   5 0.03687 0.4561 0.07098, 0.24684 2.71
BXD48a m 0.02002 0.00604722   5 0.0027044 0.3021 0.01238, 0.02775 -0.7
BXD49 m 0.06429 0.05215   5 0.02332 0.8111 0.01112, 0.1497 0.24
BXD51 m 0.16974 0.23267   5 0.10405 1.3707 0.05412, 0.58542 2.48
BXD53 m 0.03033 0.02398   5 0.01073 0.7908 0.00118403, 0.06309 -0.48
BXD55 m 0.05918 0.02546   5 0.01138 0.4302 0.02724, 0.09691 0.13
BXD6 m 0.04911 0.08105   5 0.03624 1.6504 0.00627219, 0.19359 -0.08
BXD62 m 0.0227 0.01133   5 0.00506798 0.4992 0.01075, 0.04123 -0.64
BXD63 m 0.05941 0.02086   5 0.00932802 0.3511 0.03776, 0.08127 0.14
BXD64 m 0.01119 0.0044356   5 0.00198366 0.3965 0.00532738, 0.01733 -0.88
BXD66 m 0.0096325 0.0039762   5 0.00177821 0.4128 0.0057157, 0.01607 -0.92
BXD67 m 0.02038 0.01688   5 0.00755038 0.8284 0.00552554, 0.04095 -0.69
BXD69 m 0.03221 0.01728   5 0.00772987 0.5365 0.00873399, 0.05342 -0.44
BXD73 m 0.03674 0.02902   5 0.01298 0.7899 0.01205, 0.07925 -0.34
BXD75 m 0.06909 0.05577   5 0.02494 0.8071 0.01832, 0.16401 0.34
BXD77 m 0.03781 0.02343   5 0.01048 0.6197 0.01797, 0.07846 -0.32
BXD79 m 0.01102 0.00859825   5 0.00384525 0.7801 0.00568571, 0.02628 -0.89
BXD8 m 0.07648 0.03323   4 0.01661 0.4344 0.03623, 0.10525 0.5
BXD81 m 0.08727 0.09672   5 0.04326 1.1084 0.00548563, 0.24935 0.73
BXD84 m 0.01821 0.00319193   3 0.00184286 0.1753 0.01625, 0.02189 -0.73
BXD87 m 0.06107 0.06525   5 0.02918 1.0684 0.0146, 0.16757 0.17
BXD89 m 0.02961 0.01154   5 0.0051597 0.3897 0.01712, 0.0442 -0.49
BXD90 m 0.0685 0.05615   5 0.02511 0.8197 0.02165, 0.16568 0.33
C57BL/6J m 0.03692 0.02141   4 0.0107 0.5798 0.01748, 0.05551 -0.34
DBA/2J m 0.13334 0.06933   5 0.031 0.5199 0.05227, 0.21672 1.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.046208 0.0307649671 0.1070516378 -0.0146356378
BXD100 m 0.008612425 0.0343962788 0.07663768 -0.05941283
BXD11 m 0.01646454 0.0397174017 0.0950133386 -0.0620842586
BXD12 m 0.0351275 0.0343962788 0.103152755 -0.032897755
BXD27 m 0.1855 0.0280844441 0.2410423882 0.1299576118
BXD32 m 0.0741375 0.0343962788 0.142162755 0.006112245
BXD34 m 0.0185825 0.0343962788 0.086607755 -0.049442755
BXD39 m 0.024368 0.0307649671 0.0852116378 -0.0364756378
BXD40 m 0.013558752 0.0307649671 0.0744023898 -0.0472848858
BXD43 m 0.07098 0.0307649671 0.1318236378 0.0101363622
BXD45 m 0.01416 0.0307649671 0.0750036378 -0.0466836378
BXD48 m 0.18073 0.0307649671 0.2415736378 0.1198863622
BXD48a m 0.020016 0.0307649671 0.0808596378 -0.0408276378
BXD49 m 0.064292 0.0307649671 0.1251356378 0.0034483622
BXD51 m 0.169742 0.0307649671 0.2305856378 0.1088983622
BXD53 m 0.030328806 0.0307649671 0.0911724438 -0.0305148318
BXD55 m 0.059178 0.0307649671 0.1200216378 -0.0016656378
BXD6 m 0.049106614 0.0307649671 0.1099502518 -0.0117370238
BXD62 m 0.022702 0.0307649671 0.0835456378 -0.0381416378
BXD63 m 0.05941 0.0307649671 0.1202536378 -0.0014336378
BXD64 m 0.011187464 0.0307649671 0.0720311018 -0.0496561738
BXD66 m 0.0096325 0.0307649671 0.0704761378 -0.0512111378
BXD67 m 0.020380648 0.0307649671 0.0812242858 -0.0404629898
BXD69 m 0.032214798 0.0307649671 0.0930584358 -0.0286288398
BXD73 m 0.03674 0.0307649671 0.0975836378 -0.0241036378
BXD75 m 0.069092 0.0307649671 0.1299356378 0.0082483622
BXD77 m 0.037814 0.0307649671 0.0986576378 -0.0230296378
BXD79 m 0.011021624 0.0307649671 0.0718652618 -0.0498220138
BXD8 m 0.0764825 0.0343962788 0.144507755 0.008457245
BXD81 m 0.087267126 0.0307649671 0.1481107638 0.0264234882
BXD84 m 0.0182066667 0.0397174017 0.0967554653 -0.060342132
BXD87 m 0.061068 0.0307649671 0.1219116378 0.0002243622
BXD89 m 0.029608 0.0307649671 0.0904516378 -0.0312356378
BXD90 m 0.0685 0.0307649671 0.1293436378 0.0076563622
C57BL/6J m 0.0369225 0.0343962788 0.104947755 -0.031102755
DBA/2J m 0.133342 0.0307649671 0.1941856378 0.0724983622




  GWAS USING LINEAR MIXED MODELS