Project measure / variable:   Schoonjans1   TDCA_feces_CD

ID, description, units MPD:112796   TDCA_feces_CD   bile acid taurodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurodeoxycholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.20875   ng/mL
Median of the strain means0.19007   ng/mL
SD of the strain means± 0.13337
Coefficient of variation (CV)0.6389
Min–max range of strain means0.02817   –   0.57212   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 2.8762 0.0822 2.2357 0.0005
Residuals 139 5.1092 0.0368


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.2919 0.11942   5 0.05341 0.4091 0.16772, 0.4403 0.62
BXD100 m 0.19984 0.10506   5 0.04698 0.5257 0.08546, 0.35542 -0.07
BXD11 m 0.5678 0.69915   4 0.34957 1.2313 0.19689, 1.616 2.69
BXD12 m 0.11059 0.068   4 0.034 0.6149 0.04466, 0.19529 -0.74
BXD27 m 0.37544 0.2225   4 0.11125 0.5926 0.10061, 0.5876 1.25
BXD32 m 0.42372 0.49067   4 0.24534 1.158 0.12775, 1.1574 1.61
BXD34 m 0.02817 0.00505523   4 0.00252762 0.1795 0.02322, 0.03511 -1.35
BXD39 m 0.07298 0.01398   5 0.00625368 0.1916 0.0521, 0.08533 -1.02
BXD40 m 0.03013 0.00698984   5 0.00312595 0.232 0.02334, 0.03909 -1.34
BXD43 m 0.19085 0.14848   4 0.07424 0.778 0.07518, 0.40437 -0.13
BXD45 m 0.25966 0.32018   3 0.18485 1.2331 0.07289, 0.62936 0.38
BXD48 m 0.35677 0.39318   5 0.17584 1.1021 0.11568, 1.0306 1.11
BXD48a m 0.11918 0.01003   4 0.00501725 0.0842 0.11002, 0.13233 -0.67
BXD49 m 0.2688 0.14851   5 0.06642 0.5525 0.08071, 0.43947 0.45
BXD51 m 0.17179 0.10335   5 0.04622 0.6016 0.08771, 0.3459 -0.28
BXD53 m 0.09657 0.04719   5 0.0211 0.4886 0.05345, 0.15537 -0.84
BXD55 m 0.25931 0.06672   5 0.02984 0.2573 0.1609, 0.32512 0.38
BXD6 m 0.1049 0.1986   5 0.08882 1.8932 0.0123, 0.46011 -0.78
BXD62 m 0.10035 0.03634   5 0.01625 0.3621 0.06062, 0.14932 -0.81
BXD63 m 0.26581 0.26214   5 0.11723 0.9862 0.09109, 0.71489 0.43
BXD64 m 0.06252 0.01196   5 0.00535063 0.1914 0.04941, 0.07825 -1.1
BXD66 m 0.09735 0.05595   5 0.02502 0.5747 0.04959, 0.1931 -0.84
BXD67 m 0.06774 0.04638   4 0.02319 0.6847 0.03262, 0.13603 -1.06
BXD69 m 0.23141 0.09918   5 0.04435 0.4286 0.10864, 0.35122 0.17
BXD73 m 0.15195 0.05957   5 0.02664 0.392 0.08906, 0.24464 -0.43
BXD75 m 0.19319 0.07604   5 0.03401 0.3936 0.1014, 0.3 -0.12
BXD77 m 0.07733 0.02548   5 0.0114 0.3295 0.05618, 0.11924 -0.99
BXD79 m 0.27191 0.14655   5 0.06554 0.539 0.13323, 0.50487 0.47
BXD8 m 0.29581 0.1773   5 0.07929 0.5994 0.10888, 0.49457 0.65
BXD81 m 0.15656 0.10442   5 0.0467 0.667 0.01147, 0.28304 -0.39
BXD84 m 0.18929 0.08339   5 0.03729 0.4405 0.11132, 0.32456 -0.15
BXD87 m 0.26621 0.07724   5 0.03454 0.2902 0.18523, 0.36517 0.43
BXD89 m 0.2905 0.12632   5 0.05649 0.4348 0.18423, 0.49236 0.61
BXD90 m 0.18312 0.13763   5 0.06155 0.7516 0.05471, 0.37899 -0.19
C57BL/6J m 0.11349 0.07021   10 0.0222 0.6186 0.008925, 0.22153 -0.71
DBA/2J m 0.57212 0.38102   5 0.1704 0.666 0.17165, 1.0297 2.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.291896 0.0857398875 0.4614189956 0.1223730044
BXD100 m 0.199842 0.0857398875 0.3693649956 0.0303190044
BXD11 m 0.5677975 0.0958601084 0.757329971 0.378265029
BXD12 m 0.1105925 0.0958601084 0.300124971 -0.078939971
BXD27 m 0.3754375 0.0958601084 0.564969971 0.185905029
BXD32 m 0.4237225 0.0958601084 0.613254971 0.234190029
BXD34 m 0.0281675 0.0958601084 0.217699971 -0.161364971
BXD39 m 0.072984 0.0857398875 0.2425069956 -0.0965389956
BXD40 m 0.03013 0.0857398875 0.1996529956 -0.1393929956
BXD43 m 0.1908525 0.0958601084 0.380384971 0.001320029
BXD45 m 0.25966 0.1106897188 0.4785132463 0.0408067537
BXD48 m 0.356772 0.0857398875 0.5262949956 0.1872490044
BXD48a m 0.1191825 0.0958601084 0.308714971 -0.070349971
BXD49 m 0.268802 0.0857398875 0.4383249956 0.0992790044
BXD51 m 0.17179 0.0857398875 0.3413129956 0.0022670044
BXD53 m 0.09657 0.0857398875 0.2660929956 -0.0729529956
BXD55 m 0.25931 0.0857398875 0.4288329956 0.0897870044
BXD6 m 0.104902 0.0857398875 0.2744249956 -0.0646209956
BXD62 m 0.100346 0.0857398875 0.2698689956 -0.0691769956
BXD63 m 0.265806 0.0857398875 0.4353289956 0.0962830044
BXD64 m 0.062522 0.0857398875 0.2320449956 -0.1070009956
BXD66 m 0.097352 0.0857398875 0.2668749956 -0.0721709956
BXD67 m 0.067735 0.0958601084 0.257267471 -0.121797471
BXD69 m 0.231412 0.0857398875 0.4009349956 0.0618890044
BXD73 m 0.151952 0.0857398875 0.3214749956 -0.0175709956
BXD75 m 0.193192 0.0857398875 0.3627149956 0.0236690044
BXD77 m 0.077326 0.0857398875 0.2468489956 -0.0921969956
BXD79 m 0.27191 0.0857398875 0.4414329956 0.1023870044
BXD8 m 0.295806 0.0857398875 0.4653289956 0.1262830044
BXD81 m 0.156562 0.0857398875 0.3260849956 -0.0129609956
BXD84 m 0.189294 0.0857398875 0.3588169956 0.0197710044
BXD87 m 0.266206 0.0857398875 0.4357289956 0.0966830044
BXD89 m 0.290498 0.0857398875 0.4600209956 0.1209750044
BXD90 m 0.18312 0.0857398875 0.3526429956 0.0135970044
C57BL/6J m 0.1134865 0.0606272559 0.2333573598 -0.0063843598
DBA/2J m 0.572122 0.0857398875 0.7416449956 0.4025990044




  GWAS USING LINEAR MIXED MODELS