Project measure / variable:   Schoonjans1   TCA_feces_HFD

ID, description, units MPD:112793   TCA_feces_HFD   bile acid taurocholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurocholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means7.4402   ng/mL
Median of the strain means1.9298   ng/mL
SD of the strain means± 18.212
Coefficient of variation (CV)2.4478
Min–max range of strain means0.42815   –   101.6   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 57765.224 1650.435 4.1501 < 0.0001
Residuals 136 54085.595 397.6882


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 13.245 10.547   5 4.717 0.7963 2.2945, 26.871 0.32
BXD100 m 7.4392 1.6461   4 0.82307 0.2213 5.2071, 8.7618 0.0
BXD11 m 4.9821 5.2738   3 3.0448 1.0585 1.8108, 11.07 -0.13
BXD12 m 1.3659 0.6504   4 0.3252 0.4762 0.42871, 1.8904 -0.33
BXD27 m 8.3261 9.1733   6 3.745 1.1018 0.98467, 25.466 0.05
BXD32 m 0.98194 0.3433   4 0.17165 0.3496 0.61282, 1.3691 -0.35
BXD34 m 1.2437 0.57668   4 0.28834 0.4637 0.73917, 2.0735 -0.34
BXD39 m 1.5361 0.54184   5 0.24232 0.3527 0.77885, 2.2405 -0.32
BXD40 m 1.131 0.176   5 0.07871 0.1556 0.90213, 1.3403 -0.35
BXD43 m 4.3074 2.1462   5 0.9598 0.4983 1.5801, 6.6967 -0.17
BXD45 m 0.59811 0.16654   5 0.07448 0.2784 0.44792, 0.82062 -0.38
BXD48 m 49.58 41.686   5 18.643 0.8408 2.1005, 106.8 2.31
BXD48a m 2.4531 2.0781   5 0.92936 0.8472 0.61595, 5.9704 -0.27
BXD49 m 1.2931 0.91087   5 0.40735 0.7044 0.60851, 2.8813 -0.34
BXD51 m 101.6 102.2   5 45.696 1.0059 12.749, 277.0 5.17
BXD53 m 1.2466 1.3541   5 0.60556 1.0862 0.18187, 3.6055 -0.34
BXD55 m 1.6534 0.43968   5 0.19663 0.2659 1.1248, 2.1475 -0.32
BXD6 m 1.7719 1.2314   5 0.55071 0.695 0.83206, 3.3827 -0.31
BXD62 m 0.56967 0.16623   5 0.07434 0.2918 0.39217, 0.74288 -0.38
BXD63 m 2.0876 2.519   5 1.1265 1.2066 0.55522, 6.552 -0.29
BXD64 m 0.68083 0.33328   5 0.14905 0.4895 0.42696, 1.2461 -0.37
BXD66 m 2.2328 1.0589   5 0.47355 0.4742 1.3635, 3.5285 -0.29
BXD67 m 0.62858 0.31356   5 0.14023 0.4988 0.37171, 1.1583 -0.37
BXD69 m 0.42815 0.1952   5 0.0873 0.4559 0.23366, 0.70423 -0.39
BXD73 m 1.1451 0.53202   5 0.23792 0.4646 0.69358, 1.9719 -0.35
BXD75 m 13.72 20.986   5 9.3852 1.5296 0.64295, 50.64 0.34
BXD77 m 3.6729 2.4812   5 1.1096 0.6756 0.5007, 6.6506 -0.21
BXD79 m 1.3299 0.56196   5 0.25131 0.4226 0.39784, 1.889 -0.34
BXD8 m 2.7699 1.1515   4 0.57574 0.4157 1.341, 4.0039 -0.26
BXD81 m 10.753 23.03   5 10.299 2.1418 0.40408, 51.95 0.18
BXD84 m 0.63067 0.06397   3 0.03693 0.1014 0.57127, 0.69839 -0.37
BXD87 m 5.3944 4.6303   5 2.0707 0.8583 1.7537, 13.165 -0.11
BXD89 m 1.3873 0.74617   5 0.3337 0.5379 0.63352, 2.464 -0.33
BXD90 m 5.9854 4.7248   5 2.113 0.7894 2.2044, 12.139 -0.08
C57BL/6J m 4.3248 5.2978   5 2.3693 1.225 0.39198, 11.935 -0.17
DBA/2J m 5.35 6.1373   5 2.7447 1.1472 0.54905, 15.904 -0.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 13.24486 8.9183877269 30.881513759 -4.391793759
BXD100 m 7.43925 9.9710606036 27.1576283503 -12.2791283503
BXD11 m 4.9821333333 11.5135890472 27.7509554304 -17.7866887638
BXD12 m 1.3658775 9.9710606036 21.0842558503 -18.3525008503
BXD27 m 8.3261116667 8.141336891 24.4261001711 -7.7738768378
BXD32 m 0.9819425 9.9710606036 20.7003208503 -18.7364358503
BXD34 m 1.2437425 9.9710606036 20.9621208503 -18.4746358503
BXD39 m 1.53613 8.9183877269 19.172783759 -16.100523759
BXD40 m 1.130986 8.9183877269 18.767639759 -16.505667759
BXD43 m 4.30736 8.9183877269 21.944013759 -13.329293759
BXD45 m 0.59811 8.9183877269 18.234763759 -17.038543759
BXD48 m 49.5803 8.9183877269 67.216953759 31.943646241
BXD48a m 2.45305 8.9183877269 20.089703759 -15.183603759
BXD49 m 1.293144 8.9183877269 18.929797759 -16.343509759
BXD51 m 101.5758 8.9183877269 119.212453759 83.939146241
BXD53 m 1.246602 8.9183877269 18.883255759 -16.390051759
BXD55 m 1.6534 8.9183877269 19.290053759 -15.983253759
BXD6 m 1.771898 8.9183877269 19.408551759 -15.864755759
BXD62 m 0.569672 8.9183877269 18.206325759 -17.066981759
BXD63 m 2.087632 8.9183877269 19.724285759 -15.549021759
BXD64 m 0.680834 8.9183877269 18.317487759 -16.955819759
BXD66 m 2.23282 8.9183877269 19.869473759 -15.403833759
BXD67 m 0.628582 8.9183877269 18.265235759 -17.008071759
BXD69 m 0.428154 8.9183877269 18.064807759 -17.208499759
BXD73 m 1.145052 8.9183877269 18.781705759 -16.491601759
BXD75 m 13.71958 8.9183877269 31.356233759 -3.917073759
BXD77 m 3.67288 8.9183877269 21.309533759 -13.963773759
BXD79 m 1.329908 8.9183877269 18.966561759 -16.306745759
BXD8 m 2.7699 9.9710606036 22.4882783503 -16.9484783503
BXD81 m 10.752772 8.9183877269 28.389425759 -6.883881759
BXD84 m 0.6306733333 11.5135890472 23.3994954304 -22.1381487638
BXD87 m 5.3944 8.9183877269 23.031053759 -12.242253759
BXD89 m 1.387296 8.9183877269 19.023949759 -16.249357759
BXD90 m 5.98536 8.9183877269 23.622013759 -11.651293759
C57BL/6J m 4.324836 8.9183877269 21.961489759 -13.311817759
DBA/2J m 5.34997 8.9183877269 22.986623759 -12.286683759




  GWAS USING LINEAR MIXED MODELS