Project measure / variable:   Schoonjans1   TCA_feces_CD

ID, description, units MPD:112792   TCA_feces_CD   bile acid taurocholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurocholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means1.2628   ng/mL
Median of the strain means0.98236   ng/mL
SD of the strain means± 1.1028
Coefficient of variation (CV)0.8733
Min–max range of strain means0.308   –   5.7255   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 211.2554 6.0359 1.8312 0.0074
Residuals 139 458.1596 3.2961


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.6704 0.76591   5 0.34253 0.4585 0.84617, 2.711 0.37
BXD100 m 1.7008 0.57308   5 0.25629 0.337 0.99003, 2.5638 0.4
BXD11 m 2.385 1.2697   4 0.63486 0.5324 1.5221, 4.26 1.02
BXD12 m 0.47063 0.29562   4 0.14781 0.6281 0.31372, 0.91395 -0.72
BXD27 m 1.5909 0.98481   4 0.4924 0.619 0.71767, 3.0014 0.3
BXD32 m 2.1105 2.7323   4 1.3661 1.2946 0.62992, 6.2034 0.77
BXD34 m 0.41187 0.15045   4 0.07523 0.3653 0.20295, 0.5556 -0.77
BXD39 m 1.1348 0.26308   5 0.11765 0.2318 0.83233, 1.4502 -0.12
BXD40 m 0.6406 0.13063   5 0.05842 0.2039 0.48702, 0.83069 -0.56
BXD43 m 1.36 0.8263   4 0.41315 0.6076 0.72114, 2.5536 0.09
BXD45 m 0.5363 0.34314   3 0.19811 0.6398 0.22414, 0.90372 -0.66
BXD48 m 0.6775 0.33638   5 0.15043 0.4965 0.42698, 1.267 -0.53
BXD48a m 0.95393 0.06272   4 0.03136 0.0657 0.88244, 1.02 -0.28
BXD49 m 0.308 0.09291   5 0.04155 0.3016 0.18319, 0.39391 -0.87
BXD51 m 1.1513 0.24113   5 0.10784 0.2094 0.91255, 1.4385 -0.1
BXD53 m 0.56778 0.19291   5 0.08627 0.3398 0.32855, 0.7923 -0.63
BXD55 m 0.52911 0.14987   5 0.06702 0.2832 0.32805, 0.71246 -0.67
BXD6 m 1.0108 0.23566   5 0.10539 0.2331 0.71601, 1.307 -0.23
BXD62 m 1.2604 0.81481   5 0.36439 0.6465 0.76436, 2.7015 0.0
BXD63 m 0.43767 0.13963   5 0.06244 0.319 0.33798, 0.66165 -0.75
BXD64 m 0.59259 0.14981   5 0.067 0.2528 0.47948, 0.84509 -0.61
BXD66 m 1.4823 0.94338   5 0.42189 0.6364 0.53184, 2.8298 0.2
BXD67 m 0.45387 0.06132   4 0.03066 0.1351 0.36693, 0.50237 -0.73
BXD69 m 0.79377 0.37129   5 0.16605 0.4678 0.49054, 1.3937 -0.43
BXD73 m 0.82242 0.46142   5 0.20636 0.5611 0.198, 1.277 -0.4
BXD75 m 0.79478 0.23051   5 0.10309 0.29 0.53812, 1.1397 -0.42
BXD77 m 0.71659 0.24232   5 0.10837 0.3382 0.41879, 1.0566 -0.5
BXD79 m 1.8961 0.666   5 0.29784 0.3512 1.3739, 2.9071 0.57
BXD8 m 1.2661 0.69462   5 0.31064 0.5486 0.53636, 2.3958 0.0
BXD81 m 1.1106 0.33286   5 0.14886 0.2997 0.78869, 1.6056 -0.14
BXD84 m 0.39919 0.13363   5 0.05976 0.3348 0.20497, 0.55909 -0.78
BXD87 m 1.9621 0.64627   5 0.28902 0.3294 0.98792, 2.7371 0.63
BXD89 m 1.69 1.5821   5 0.70755 0.9362 0.84525, 4.5078 0.39
BXD90 m 5.7255 9.5266   5 4.2604 1.6639 0.79361, 22.722 4.05
C57BL/6J m 0.40207 0.19016   10 0.06013 0.473 0.17854, 0.83955 -0.78
DBA/2J m 4.4444 2.8595   5 1.2788 0.6434 0.71773, 8.4244 2.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.670422 0.8119251153 3.2757422519 0.0651017481
BXD100 m 1.700786 0.8119251153 3.3061062519 0.0954657481
BXD11 m 2.384975 0.9077598752 4.1797776044 0.5901723956
BXD12 m 0.4706275 0.9077598752 2.2654301044 -1.3241751044
BXD27 m 1.5909425 0.9077598752 3.3857451044 -0.2038601044
BXD32 m 2.11053 0.9077598752 3.9053326044 0.3157273956
BXD34 m 0.4118675 0.9077598752 2.2066701044 -1.3829351044
BXD39 m 1.134762 0.8119251153 2.7400822519 -0.4705582519
BXD40 m 0.6406 0.8119251153 2.2459202519 -0.9647202519
BXD43 m 1.3599875 0.9077598752 3.1547901044 -0.4348151044
BXD45 m 0.5363 1.0481908166 2.6087595336 -1.5361595336
BXD48 m 0.677496 0.8119251153 2.2828162519 -0.9278242519
BXD48a m 0.9539325 0.9077598752 2.7487351044 -0.8408701044
BXD49 m 0.307996 0.8119251153 1.9133162519 -1.2973242519
BXD51 m 1.15128 0.8119251153 2.7566002519 -0.4540402519
BXD53 m 0.567778 0.8119251153 2.1730982519 -1.0375422519
BXD55 m 0.52911 0.8119251153 2.1344302519 -1.0762102519
BXD6 m 1.010822 0.8119251153 2.6161422519 -0.5944982519
BXD62 m 1.26038 0.8119251153 2.8657002519 -0.3449402519
BXD63 m 0.437672 0.8119251153 2.0429922519 -1.1676482519
BXD64 m 0.59259 0.8119251153 2.1979102519 -1.0127302519
BXD66 m 1.482296 0.8119251153 3.0876162519 -0.1230242519
BXD67 m 0.4538725 0.9077598752 2.2486751044 -1.3409301044
BXD69 m 0.793768 0.8119251153 2.3990882519 -0.8115522519
BXD73 m 0.822424 0.8119251153 2.4277442519 -0.7828962519
BXD75 m 0.794776 0.8119251153 2.4000962519 -0.8105442519
BXD77 m 0.716586 0.8119251153 2.3219062519 -0.8887342519
BXD79 m 1.89614 0.8119251153 3.5014602519 0.2908197481
BXD8 m 1.266098 0.8119251153 2.8714182519 -0.3392222519
BXD81 m 1.110642 0.8119251153 2.7159622519 -0.4946782519
BXD84 m 0.399188 0.8119251153 2.0045082519 -1.2061322519
BXD87 m 1.962144 0.8119251153 3.5674642519 0.3568237481
BXD89 m 1.68995 0.8119251153 3.2952702519 0.0846297481
BXD90 m 5.725482 0.8119251153 7.3308022519 4.1201617481
C57BL/6J m 0.402068 0.5741177548 1.5372008361 -0.7330648361
DBA/2J m 4.444446 0.8119251153 6.0497662519 2.8391257481




  GWAS USING LINEAR MIXED MODELS