Project measure / variable:   Schoonjans1   TbMCA_feces_HFD

ID, description, units MPD:112791   TbMCA_feces_HFD   bile acid tauro-β-muricholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauro-β-muricholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means11.327   ng/mL
Median of the strain means3.9553   ng/mL
SD of the strain means± 20.25
Coefficient of variation (CV)1.7878
Min–max range of strain means0.49125   –   108.5   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 72303.8436 2065.8241 5.2884 < 0.0001
Residuals 135 52735.7739 390.6354


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 24.403 26.949   5 12.052 1.1043 4.5807, 70.13 0.65
BXD100 m 19.992 4.9346   4 2.4673 0.2468 15.056, 25.843 0.43
BXD11 m 13.893 19.625   3 11.331 1.4126 1.3521, 36.509 0.13
BXD12 m 3.2719 2.5828   4 1.2914 0.7894 0.67238, 6.4202 -0.4
BXD27 m 44.129 55.36   6 22.6 1.2544 1.067, 140.6 1.62
BXD32 m 5.468 4.8792   4 2.4396 0.8923 1.9856, 12.581 -0.29
BXD34 m 3.1329 1.9712   4 0.98562 0.6292 1.8202, 6.0209 -0.4
BXD39 m 1.1695 0.60072   5 0.26865 0.5136 0.30733, 1.993 -0.5
BXD40 m 2.0574 0.57944   5 0.25913 0.2816 1.4283, 2.7189 -0.46
BXD43 m 5.0905 1.9355   5 0.86557 0.3802 2.4553, 7.4938 -0.31
BXD45 m 1.3659 0.3233   5 0.14459 0.2367 0.96856, 1.6891 -0.49
BXD48 m 50.59 41.322   5 18.48 0.8168 2.2656, 112.8 1.94
BXD48a m 3.874 4.9248   5 2.2024 1.2712 0.64728, 12.492 -0.37
BXD49 m 1.7705 0.7276   5 0.32539 0.411 1.223, 3.0455 -0.47
BXD51 m 108.5 64.15   5 28.691 0.5913 36.317, 205.7 4.8
BXD53 m 2.0946 3.2505   5 1.4537 1.5519 0.31403, 7.8897 -0.46
BXD55 m 2.3022 1.049   5 0.46913 0.4556 1.1594, 3.4406 -0.45
BXD6 m 7.4892 9.6976   5 4.3369 1.2949 0.82142, 23.21 -0.19
BXD62 m 1.3697 0.68724   5 0.30734 0.5017 0.79433, 2.4913 -0.49
BXD63 m 3.2992 3.4771   5 1.555 1.0539 0.82542, 9.4156 -0.4
BXD64 m 1.0269 0.33059   5 0.14784 0.3219 0.57799, 1.3924 -0.51
BXD66 m 2.7113 1.7292   5 0.77334 0.6378 1.2099, 4.7764 -0.43
BXD67 m 1.1469 1.0037   5 0.44885 0.8751 0.295, 2.8404 -0.5
BXD69 m 0.49125 0.27885   5 0.1247 0.5676 0.22026, 0.94114 -0.54
BXD73 m 4.0366 3.3283   5 1.4885 0.8245 1.1027, 9.5824 -0.36
BXD75 m 23.936 28.226   5 12.623 1.1792 0.8438, 70.0 0.62
BXD77 m 6.24 4.7015   5 2.1026 0.7534 1.2682, 12.533 -0.25
BXD79 m 1.5043 0.67552   5 0.3021 0.4491 0.60095, 2.3048 -0.49
BXD8 m 8.6766 5.9066   4 2.9533 0.6808 3.1826, 16.397 -0.13
BXD81 m 10.247 21.688   5 9.6993 2.1166 0.3689, 49.043 -0.05
BXD84 m 0.7939 0.34012   3 0.19637 0.4284 0.53347, 1.1787 -0.52
BXD87 m 8.7198 10.829   5 4.8428 1.2419 1.1574, 27.138 -0.13
BXD89 m 2.714 2.4178   5 1.0813 0.8909 0.76587, 6.7911 -0.43
BXD90 m 4.1817 3.0902   5 1.382 0.739 1.391, 7.6348 -0.35
C57BL/6J m 7.5262 8.2846   4 4.1423 1.1008 0.23383, 15.942 -0.19
DBA/2J m 18.556 30.073   5 13.449 1.6207 1.5649, 72.04 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 24.40326 8.8389520005 41.8839871102 6.9225328898
BXD100 m 19.99225 9.8822487615 39.5362970573 0.4482029427
BXD11 m 13.8925666667 11.4110379652 36.4600883258 -8.6749549925
BXD12 m 3.271945 9.8822487615 22.8159920573 -16.2721020573
BXD27 m 44.1289666667 8.0688223256 60.0866142664 28.1713190669
BXD32 m 5.46805 9.8822487615 25.0120970573 -14.0759970573
BXD34 m 3.13285 9.8822487615 22.6768970573 -16.4111970573
BXD39 m 1.169526 8.8389520005 18.6502531102 -16.3112011102
BXD40 m 2.05742 8.8389520005 19.5381471102 -15.4233071102
BXD43 m 5.0905 8.8389520005 22.5712271102 -12.3902271102
BXD45 m 1.365912 8.8389520005 18.8466391102 -16.1148151102
BXD48 m 50.58932 8.8389520005 68.0700471102 33.1085928898
BXD48a m 3.873996 8.8389520005 21.3547231102 -13.6067311102
BXD49 m 1.77046 8.8389520005 19.2511871102 -15.7102671102
BXD51 m 108.4934 8.8389520005 125.9741271102 91.0126728898
BXD53 m 2.094568 8.8389520005 19.5752951102 -15.3861591102
BXD55 m 2.30224 8.8389520005 19.7829671102 -15.1784871102
BXD6 m 7.489204 8.8389520005 24.9699311102 -9.9915231102
BXD62 m 1.369692 8.8389520005 18.8504191102 -16.1110351102
BXD63 m 3.299164 8.8389520005 20.7798911102 -14.1815631102
BXD64 m 1.026934 8.8389520005 18.5076611102 -16.4537931102
BXD66 m 2.71132 8.8389520005 20.1920471102 -14.7694071102
BXD67 m 1.146918 8.8389520005 18.6276451102 -16.3338091102
BXD69 m 0.49125 8.8389520005 17.9719771102 -16.9894771102
BXD73 m 4.03658 8.8389520005 21.5173071102 -13.4441471102
BXD75 m 23.93608 8.8389520005 41.4168071102 6.4553528898
BXD77 m 6.23996 8.8389520005 23.7206871102 -11.2407671102
BXD79 m 1.50429 8.8389520005 18.9850171102 -15.9764371102
BXD8 m 8.676575 9.8822487615 28.2206220573 -10.8674720573
BXD81 m 10.246936 8.8389520005 27.7276631102 -7.2337911102
BXD84 m 0.7938966667 11.4110379652 23.3614183258 -21.7736249925
BXD87 m 8.71984 8.8389520005 26.2005671102 -8.7608871102
BXD89 m 2.713974 8.8389520005 20.1947011102 -14.7667531102
BXD90 m 4.18166 8.8389520005 21.6623871102 -13.2990671102
C57BL/6J m 7.52621 9.8822487615 27.0702570573 -12.0178370573
DBA/2J m 18.5561 8.8389520005 36.0368271102 1.0753728898




  GWAS USING LINEAR MIXED MODELS