Project measure / variable:   Schoonjans1   TaMCA_feces_HFD

ID, description, units MPD:112789   TaMCA_feces_HFD   bile acid tauro-α-muricholic acid in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauro-α-muricholic acid in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means4.4157   ng/mL
Median of the strain means1.2772   ng/mL
SD of the strain means± 8.2613
Coefficient of variation (CV)1.8709
Min–max range of strain means0.20675   –   37.138   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 11940.4813 341.1566 5.4785 < 0.0001
Residuals 136 8469.0033 62.2721


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 6.4874 5.7072   5 2.5524 0.8797 1.139, 14.863 0.25
BXD100 m 2.7104 1.2727   4 0.63634 0.4696 1.4351, 4.4507 -0.21
BXD11 m 4.4311 5.1854   3 2.9938 1.1702 0.80764, 10.371 0.0
BXD12 m 1.3017 1.1263   4 0.56313 0.8652 0.28045, 2.8145 -0.38
BXD27 m 13.372 13.939   6 5.6906 1.0424 0.69251, 36.066 1.08
BXD32 m 1.2528 1.1121   4 0.55603 0.8877 0.44113, 2.8302 -0.38
BXD34 m 1.0789 0.83065   4 0.41533 0.7699 0.50287, 2.3059 -0.4
BXD39 m 0.42791 0.20342   5 0.09097 0.4754 0.14756, 0.71682 -0.48
BXD40 m 0.76987 0.40594   5 0.18154 0.5273 0.39284, 1.4197 -0.44
BXD43 m 2.7301 0.85342   5 0.38166 0.3126 1.4417, 3.8164 -0.2
BXD45 m 0.42686 0.11836   5 0.05293 0.2773 0.32271, 0.62757 -0.48
BXD48 m 37.138 27.807   5 12.436 0.7488 1.5513, 72.26 3.96
BXD48a m 2.1709 2.5079   5 1.1216 1.1552 0.4217, 6.5755 -0.27
BXD49 m 0.49039 0.28947   5 0.12945 0.5903 0.26894, 0.98375 -0.48
BXD51 m 34.124 22.172   5 9.9156 0.6497 14.055, 70.35 3.6
BXD53 m 0.78934 1.1385   5 0.50914 1.4423 0.14927, 2.8162 -0.44
BXD55 m 1.0302 0.46398   5 0.2075 0.4504 0.39556, 1.4655 -0.41
BXD6 m 0.79862 0.77324   5 0.3458 0.9682 0.21528, 1.9859 -0.44
BXD62 m 0.37677 0.16722   5 0.07478 0.4438 0.19503, 0.64543 -0.49
BXD63 m 0.93347 1.166   5 0.52146 1.2491 0.23592, 2.993 -0.42
BXD64 m 0.30923 0.13325   5 0.05959 0.4309 0.18485, 0.53045 -0.5
BXD66 m 1.2189 1.0013   5 0.44778 0.8215 0.37134, 2.7935 -0.39
BXD67 m 0.35724 0.40123   5 0.17944 1.1231 0.07143, 1.065 -0.49
BXD69 m 0.21923 0.15916   5 0.07118 0.726 0.0951, 0.49182 -0.51
BXD73 m 1.2182 0.9982   5 0.44641 0.8194 0.37763, 2.9157 -0.39
BXD75 m 12.023 17.776   5 7.9496 1.4784 0.38348, 42.973 0.92
BXD77 m 3.819 3.2267   5 1.443 0.8449 0.59584, 9.0177 -0.07
BXD79 m 0.41212 0.20909   5 0.09351 0.5073 0.09573, 0.66803 -0.48
BXD8 m 1.5166 1.0375   4 0.51874 0.6841 0.47648, 2.7755 -0.35
BXD81 m 4.2119 8.864   5 3.9641 2.1045 0.12117, 20.067 -0.02
BXD84 m 0.20675 0.15599   3 0.09006 0.7545 0.10518, 0.38636 -0.51
BXD87 m 3.8922 5.2627   5 2.3536 1.3521 0.3601, 12.851 -0.06
BXD89 m 2.1288 1.78   5 0.79602 0.8361 0.585, 4.9953 -0.28
BXD90 m 5.9553 4.8893   5 2.1866 0.821 1.2987, 11.678 0.19
C57BL/6J m 3.1101 4.0793   5 1.8243 1.3116 0.05778, 8.7635 -0.16
DBA/2J m 5.5259 8.3469   5 3.7329 1.5105 0.52675, 20.298 0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 6.48744 3.5290815501 13.4664132508 -0.4915332508
BXD100 m 2.710425 3.9456331221 10.513154301 -5.092304301
BXD11 m 4.4311133333 4.5560246903 13.440929058 -4.5787023913
BXD12 m 1.301705 3.9456331221 9.104434301 -6.501024301
BXD27 m 13.3715816667 3.2215959538 19.7424834628 7.0006798705
BXD32 m 1.252775 3.9456331221 9.055504301 -6.549954301
BXD34 m 1.07892 3.9456331221 8.881649301 -6.723809301
BXD39 m 0.42791 3.5290815501 7.4068832508 -6.5510632508
BXD40 m 0.769874 3.5290815501 7.7488472508 -6.2090992508
BXD43 m 2.73008 3.5290815501 9.7090532508 -4.2488932508
BXD45 m 0.426862 3.5290815501 7.4058352508 -6.5521112508
BXD48 m 37.13766 3.5290815501 44.1166332508 30.1586867492
BXD48a m 2.170914 3.5290815501 9.1498872508 -4.8080592508
BXD49 m 0.49039 3.5290815501 7.4693632508 -6.4885832508
BXD51 m 34.1244 3.5290815501 41.1033732508 27.1454267492
BXD53 m 0.78934 3.5290815501 7.7683132508 -6.1896332508
BXD55 m 1.030188 3.5290815501 8.0091612508 -5.9487852508
BXD6 m 0.798618 3.5290815501 7.7775912508 -6.1803552508
BXD62 m 0.37677 3.5290815501 7.3557432508 -6.6022032508
BXD63 m 0.93347 3.5290815501 7.9124432508 -6.0455032508
BXD64 m 0.30923 3.5290815501 7.2882032508 -6.6697432508
BXD66 m 1.218866 3.5290815501 8.1978392508 -5.7601072508
BXD67 m 0.357244 3.5290815501 7.3362172508 -6.6217292508
BXD69 m 0.219234 3.5290815501 7.1982072508 -6.7597392508
BXD73 m 1.218182 3.5290815501 8.1971552508 -5.7607912508
BXD75 m 12.023436 3.5290815501 19.0024092508 5.0444627492
BXD77 m 3.818988 3.5290815501 10.7979612508 -3.1599852508
BXD79 m 0.412124 3.5290815501 7.3910972508 -6.5668492508
BXD8 m 1.5165925 3.9456331221 9.319321801 -6.286136801
BXD81 m 4.211874 3.5290815501 11.1908472508 -2.7670992508
BXD84 m 0.2067533333 4.5560246903 9.216569058 -8.8030623913
BXD87 m 3.892224 3.5290815501 10.8711972508 -3.0867492508
BXD89 m 2.128786 3.5290815501 9.1077592508 -4.8501872508
BXD90 m 5.95528 3.5290815501 12.9342532508 -1.0236932508
C57BL/6J m 3.110052 3.5290815501 10.0890252508 -3.8689212508
DBA/2J m 5.52587 3.5290815501 12.5048432508 -1.4531032508




  GWAS USING LINEAR MIXED MODELS