Project measure / variable:   Schoonjans1   MDCA_feces_HFD

ID, description, units MPD:112787   MDCA_feces_HFD   bile acid murocholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid murocholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.48467   ng/mL
Median of the strain means0.3572   ng/mL
SD of the strain means± 0.45249
Coefficient of variation (CV)0.9336
Min–max range of strain means0.02034   –   2.3483   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 34.5584 0.9874 7.327 < 0.0001
Residuals 134 18.0578 0.1348


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.2932 0.46939   5 0.20992 0.363 0.86947, 2.0927 1.79
BXD100 m 0.10503 0.06386   4 0.03193 0.608 0.04702, 0.18438 -0.84
BXD11 m 0.09216 0.06445   2   0.04557 0.6993 0.04659, 0.13773 -0.87
BXD12 m 0.27808 0.17415   4 0.08707 0.6263 0.0369, 0.41124 -0.46
BXD27 m 0.35831 0.31084   6 0.1269 0.8675 0.13724, 0.93021 -0.28
BXD32 m 0.40535 0.17903   4 0.08952 0.4417 0.20017, 0.56408 -0.18
BXD34 m 0.57858 0.31628   4 0.15814 0.5467 0.37976, 1.0499 0.21
BXD39 m 0.07841 0.03563   5 0.01593 0.4544 0.0328, 0.11927 -0.9
BXD40 m 0.14701 0.06949   5 0.03108 0.4727 0.06186, 0.21857 -0.75
BXD43 m 0.13651 0.05441   5 0.02433 0.3986 0.08562, 0.22852 -0.77
BXD45 m 0.15401 0.04402   5 0.01968 0.2858 0.09308, 0.20112 -0.73
BXD48 m 2.3483 1.4083   5 0.62983 0.5997 0.7338, 3.7765 4.12
BXD48a m 0.40014 0.08047   5 0.03599 0.2011 0.33604, 0.53956 -0.19
BXD49 m 0.36198 0.30955   5 0.13843 0.8552 0.09226, 0.84668 -0.27
BXD51 m 0.76009 0.11686   5 0.05226 0.1537 0.58727, 0.87333 0.61
BXD53 m 0.14387 0.07614   5 0.03405 0.5292 0.02164, 0.20842 -0.75
BXD55 m 0.15863 0.02606   5 0.01166 0.1643 0.12951, 0.19126 -0.72
BXD6 m 0.02034 0.01123   4 0.00561526 0.552 0.00585799, 0.03081 -1.03
BXD62 m 0.15327 0.08641   5 0.03864 0.5638 0.08384, 0.29712 -0.73
BXD63 m 0.75066 0.41019   5 0.18344 0.5464 0.21576, 1.2372 0.59
BXD64 m 0.18118 0.08228   5 0.0368 0.4541 0.08944, 0.30088 -0.67
BXD66 m 0.35352 0.18011   5 0.08055 0.5095 0.23648, 0.66742 -0.29
BXD67 m 0.23512 0.11771   5 0.05264 0.5007 0.06448, 0.34405 -0.55
BXD69 m 0.79727 0.31526   5 0.14099 0.3954 0.43796, 1.24 0.69
BXD73 m 0.3561 0.25146   5 0.11246 0.7062 0.10001, 0.73452 -0.28
BXD75 m 1.2389 0.90004   5 0.40251 0.7265 0.29543, 2.5079 1.67
BXD77 m 0.62795 0.41659   5 0.1863 0.6634 0.18247, 1.0785 0.32
BXD79 m 0.20313 0.05726   5 0.02561 0.2819 0.14499, 0.29034 -0.62
BXD8 m 0.19523 0.06484   4 0.03242 0.3321 0.11532, 0.25398 -0.64
BXD81 m 0.89621 0.49033   5 0.21928 0.5471 0.46959, 1.7294 0.91
BXD84 m 0.87822 0.53832   3 0.3108 0.613 0.54788, 1.4994 0.87
BXD87 m 0.58546 0.27888   5 0.12472 0.4763 0.39626, 1.0726 0.22
BXD89 m 0.57466 0.1548   5 0.06923 0.2694 0.36749, 0.70041 0.2
BXD90 m 0.34809 0.10279   5 0.04597 0.2953 0.24529, 0.51407 -0.3
C57BL/6J m 0.65362 0.18406   5 0.08232 0.2816 0.40419, 0.88348 0.37
DBA/2J m 0.59937 0.13238   5 0.0592 0.2209 0.43887, 0.78433 0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.293154 0.164170588 1.6178548177 0.9684531823
BXD100 m 0.1050275 0.1835482974 0.4680540504 -0.2579990504
BXD11 m 0.09216 0.2595764915 0.605557071 -0.421237071
BXD12 m 0.2780775 0.1835482974 0.6411040504 -0.0849490504
BXD27 m 0.358315 0.1498665572 0.6547249372 0.0619050628
BXD32 m 0.4053475 0.1835482974 0.7683740504 0.0423209496
BXD34 m 0.578575 0.1835482974 0.9416015504 0.2155484496
BXD39 m 0.078414 0.164170588 0.4031148177 -0.2462868177
BXD40 m 0.14701 0.164170588 0.4717108177 -0.1776908177
BXD43 m 0.136508 0.164170588 0.4612088177 -0.1881928177
BXD45 m 0.154006 0.164170588 0.4787068177 -0.1706948177
BXD48 m 2.3483 0.164170588 2.6730008177 2.0235991823
BXD48a m 0.400142 0.164170588 0.7248428177 0.0754411823
BXD49 m 0.361976 0.164170588 0.6866768177 0.0372751823
BXD51 m 0.760086 0.164170588 1.0847868177 0.4353851823
BXD53 m 0.143866 0.164170588 0.4685668177 -0.1808348177
BXD55 m 0.158628 0.164170588 0.4833288177 -0.1660728177
BXD6 m 0.0203444975 0.1835482974 0.3833710479 -0.3426820529
BXD62 m 0.153274 0.164170588 0.4779748177 -0.1714268177
BXD63 m 0.750658 0.164170588 1.0753588177 0.4259571823
BXD64 m 0.181182 0.164170588 0.5058828177 -0.1435188177
BXD66 m 0.353522 0.164170588 0.6782228177 0.0288211823
BXD67 m 0.235116 0.164170588 0.5598168177 -0.0895848177
BXD69 m 0.797272 0.164170588 1.1219728177 0.4725711823
BXD73 m 0.356098 0.164170588 0.6807988177 0.0313971823
BXD75 m 1.238886 0.164170588 1.5635868177 0.9141851823
BXD77 m 0.627948 0.164170588 0.9526488177 0.3032471823
BXD79 m 0.203128 0.164170588 0.5278288177 -0.1215728177
BXD8 m 0.1952325 0.1835482974 0.5582590504 -0.1677940504
BXD81 m 0.89621 0.164170588 1.2209108177 0.5715091823
BXD84 m 0.87822 0.2119433178 1.2974069531 0.4590330469
BXD87 m 0.58546 0.164170588 0.9101608177 0.2607591823
BXD89 m 0.574658 0.164170588 0.8993588177 0.2499571823
BXD90 m 0.34809 0.164170588 0.6727908177 0.0233891823
C57BL/6J m 0.653622 0.164170588 0.9783228177 0.3289211823
DBA/2J m 0.599368 0.164170588 0.9240688177 0.2746671823




  GWAS USING LINEAR MIXED MODELS