Project measure / variable:   Schoonjans1   MCA_feces_HFD

ID, description, units MPD:112785   MCA_feces_HFD   bile acid γ-muricholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid γ-muricholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.78239   ng/mL
Median of the strain means0.62441   ng/mL
SD of the strain means± 0.63268
Coefficient of variation (CV)0.8086
Min–max range of strain means0.17807   –   2.8682   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 68.0191 1.9434 7.9699 < 0.0001
Residuals 136 33.1626 0.2438


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.34696 0.06025   5 0.02694 0.1736 0.27826, 0.41411 -0.69
BXD100 m 0.2427 0.15436   4 0.07718 0.636 0.07835, 0.44789 -0.85
BXD11 m 1.3465 1.8093   3 1.0446 1.3437 0.23732, 3.4343 0.89
BXD12 m 0.20869 0.07035   4 0.03517 0.3371 0.13401, 0.27153 -0.91
BXD27 m 0.35864 0.24594   6 0.10041 0.6858 0.12574, 0.81329 -0.67
BXD32 m 0.41953 0.15441   4 0.0772 0.368 0.24783, 0.57918 -0.57
BXD34 m 1.2397 0.68876   4 0.34438 0.5556 0.60837, 2.1416 0.72
BXD39 m 0.85476 0.38083   5 0.17031 0.4455 0.49069, 1.3428 0.11
BXD40 m 0.68847 0.28933   5 0.12939 0.4203 0.34015, 1.1402 -0.15
BXD43 m 0.47063 0.15141   5 0.06771 0.3217 0.29355, 0.67896 -0.49
BXD45 m 0.5853 0.23512   5 0.10515 0.4017 0.31963, 0.94588 -0.31
BXD48 m 2.1369 1.0266   5 0.45911 0.4804 1.1969, 3.2888 2.14
BXD48a m 0.74155 0.43509   5 0.19458 0.5867 0.25351, 1.4043 -0.06
BXD49 m 0.2622 0.06191   5 0.02769 0.2361 0.16898, 0.32409 -0.82
BXD51 m 0.73158 0.31668   5 0.14162 0.4329 0.32347, 1.1247 -0.08
BXD53 m 0.50345 0.34751   5 0.15541 0.6903 0.03828, 0.85959 -0.44
BXD55 m 0.66352 0.12094   5 0.05409 0.1823 0.48556, 0.80683 -0.19
BXD6 m 0.17807 0.03769   5 0.01685 0.2116 0.13604, 0.22433 -0.96
BXD62 m 0.39119 0.15666   5 0.07006 0.4005 0.2466, 0.63024 -0.62
BXD63 m 0.25772 0.1467   5 0.06561 0.5692 0.13262, 0.48822 -0.83
BXD64 m 0.77237 0.4632   5 0.20715 0.5997 0.40217, 1.54 -0.02
BXD66 m 2.0061 0.41561   5 0.18587 0.2072 1.3303, 2.346 1.93
BXD67 m 0.667 0.28742   5 0.12854 0.4309 0.34402, 1.087 -0.18
BXD69 m 0.76255 0.3634   5 0.16252 0.4766 0.46971, 1.3921 -0.03
BXD73 m 0.26716 0.16041   5 0.07174 0.6004 0.13248, 0.52388 -0.81
BXD75 m 1.0933 0.7385   5 0.33027 0.6755 0.3742, 2.2484 0.49
BXD77 m 2.8682 1.359   5 0.60776 0.4738 1.3359, 4.5032 3.3
BXD79 m 1.1137 0.65324   5 0.29214 0.5866 0.06326, 1.6671 0.52
BXD8 m 0.18866 0.08283   4 0.04142 0.439 0.13726, 0.31167 -0.94
BXD81 m 0.45663 0.0952   5 0.04257 0.2085 0.36105, 0.56727 -0.51
BXD84 m 0.426 0.31922   3 0.1843 0.7493 0.17868, 0.78636 -0.56
BXD87 m 0.36507 0.13109   5 0.05863 0.3591 0.2532, 0.57389 -0.66
BXD89 m 1.9625 0.58151   5 0.26006 0.2963 1.0162, 2.4094 1.87
BXD90 m 1.5029 0.58643   5 0.26226 0.3902 0.82343, 2.0967 1.14
C57BL/6J m 0.76225 0.28069   5 0.12553 0.3682 0.4974, 1.2384 -0.03
DBA/2J m 0.32364 0.22909   5 0.10245 0.7079 0.09967, 0.632 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.346962 0.2208358569 0.7836783287 -0.0897543287
BXD100 m 0.2427 0.246901994 0.7309636989 -0.2455636989
BXD11 m 1.34648 0.2850978654 1.910278356 0.782681644
BXD12 m 0.208695 0.246901994 0.6969586989 -0.2795686989
BXD27 m 0.3586383333 0.2015946339 0.7573039741 -0.0400273074
BXD32 m 0.4195325 0.246901994 0.9077961989 -0.0687311989
BXD34 m 1.239685 0.246901994 1.7279486989 0.7514213011
BXD39 m 0.854756 0.2208358569 1.2914723287 0.4180396713
BXD40 m 0.688466 0.2208358569 1.1251823287 0.2517496713
BXD43 m 0.470634 0.2208358569 0.9073503287 0.0339176713
BXD45 m 0.5853 0.2208358569 1.0220163287 0.1485836713
BXD48 m 2.13686 0.2208358569 2.5735763287 1.7001436713
BXD48a m 0.741548 0.2208358569 1.1782643287 0.3048316713
BXD49 m 0.262198 0.2208358569 0.6989143287 -0.1745183287
BXD51 m 0.731582 0.2208358569 1.1682983287 0.2948656713
BXD53 m 0.503446 0.2208358569 0.9401623287 0.0667296713
BXD55 m 0.66352 0.2208358569 1.1002363287 0.2268036713
BXD6 m 0.178074 0.2208358569 0.6147903287 -0.2586423287
BXD62 m 0.39119 0.2208358569 0.8279063287 -0.0455263287
BXD63 m 0.257724 0.2208358569 0.6944403287 -0.1789923287
BXD64 m 0.772366 0.2208358569 1.2090823287 0.3356496713
BXD66 m 2.00606 0.2208358569 2.4427763287 1.5693436713
BXD67 m 0.667 0.2208358569 1.1037163287 0.2302836713
BXD69 m 0.762554 0.2208358569 1.1992703287 0.3258376713
BXD73 m 0.267158 0.2208358569 0.7038743287 -0.1695583287
BXD75 m 1.09331 0.2208358569 1.5300263287 0.6565936713
BXD77 m 2.86816 0.2208358569 3.3048763287 2.4314436713
BXD79 m 1.113672 0.2208358569 1.5503883287 0.6769556713
BXD8 m 0.188665 0.246901994 0.6769286989 -0.2995986989
BXD81 m 0.456628 0.2208358569 0.8933443287 0.0199116713
BXD84 m 0.426 0.2850978654 0.989798356 -0.137798356
BXD87 m 0.365072 0.2208358569 0.8017883287 -0.0716443287
BXD89 m 1.96248 0.2208358569 2.3991963287 1.5257636713
BXD90 m 1.502906 0.2208358569 1.9396223287 1.0661896713
C57BL/6J m 0.762254 0.2208358569 1.1989703287 0.3255376713
DBA/2J m 0.323638 0.2208358569 0.7603543287 -0.1130783287




  GWAS USING LINEAR MIXED MODELS