Project measure / variable:   Schoonjans1   LCA_feces_HFD

ID, description, units MPD:112783   LCA_feces_HFD   bile acid 3-oxocholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid 3-oxocholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means6.4193   ng/mL
Median of the strain means5.1314   ng/mL
SD of the strain means± 4.8944
Coefficient of variation (CV)0.7624
Min–max range of strain means0.93667   –   25.466   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 3889.2178 114.3888 13.3966 < 0.0001
Residuals 131 1118.5607 8.5386


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 8.3854 2.1991   5 0.98347 0.2623 5.769, 11.357 0.4
BXD100 m 2.0018 1.0008   4 0.5004 0.4999 0.94167, 3.229 -0.9
BXD11 m 1.4176 0.0   1   0.0 0.0 1.4176, 1.4176 -1.02
BXD12 m 2.1692 0.75097   4 0.37548 0.3462 1.261, 3.1001 -0.87
BXD27 m 9.1563 10.981   6 4.483 1.1993 1.35, 28.755 0.56
BXD32 m 5.3877 1.9046   4 0.95228 0.3535 3.5998, 7.8245 -0.21
BXD34 m 3.9336 0.39973   4 0.19986 0.1016 3.448, 4.3968 -0.51
BXD39 m 2.9533 1.2074   5 0.53998 0.4088 1.7294, 4.8883 -0.71
BXD40 m 2.0252 0.8635   5 0.38617 0.4264 0.93127, 3.3158 -0.9
BXD43 m 2.6025 0.7303   5 0.3266 0.2806 1.7291, 3.3159 -0.78
BXD45 m 5.0963 2.1854   5 0.97734 0.4288 2.9315, 7.89 -0.27
BXD48 m 13.079 3.6724   5 1.6424 0.2808 8.9743, 16.965 1.36
BXD48a m 5.7989 1.3932   5 0.62305 0.2403 3.6643, 7.4105 -0.13
BXD49 m 5.7573 1.3295   5 0.59459 0.2309 4.1556, 7.8426 -0.14
BXD51 m 3.7611 1.1038   5 0.49364 0.2935 2.5557, 5.569 -0.54
BXD53 m 4.4013 2.6108   5 1.1676 0.5932 0.65457, 7.8972 -0.41
BXD55 m 6.533 1.0683   5 0.47774 0.1635 5.5134, 8.1937 0.02
BXD6 m 0.93667 0.03612   2   0.02554 0.0386 0.91113, 0.96221 -1.12
BXD62 m 4.4027 1.8449   5 0.82506 0.419 2.5668, 6.5195 -0.41
BXD63 m 10.648 2.3045   5 1.0306 0.2164 7.3173, 12.644 0.86
BXD64 m 3.214 1.4535   5 0.65003 0.4522 1.6321, 5.1271 -0.65
BXD66 m 2.9545 1.4232   5 0.63646 0.4817 1.1813, 5.1588 -0.71
BXD67 m 3.8246 1.4436   5 0.64561 0.3775 2.3449, 5.86 -0.53
BXD69 m 14.07 2.4201   5 1.0823 0.172 12.268, 18.008 1.56
BXD73 m 6.6019 4.0405   5 1.807 0.612 2.503, 12.448 0.04
BXD75 m 13.908 3.4319   5 1.5348 0.2468 10.991, 19.45 1.53
BXD77 m 5.754 0.93073   5 0.41623 0.1618 4.5901, 7.1314 -0.14
BXD79 m 3.4407 1.3786   5 0.61652 0.4007 1.9443, 5.5398 -0.61
BXD8 m 2.1581 0.59205   4 0.29602 0.2743 1.3757, 2.7862 -0.87
BXD81 m 25.466 3.2929   5 1.4726 0.1293 20.43, 28.656 3.89
BXD84 m 9.0258 2.309   3 1.3331 0.2558 7.1321, 11.598 0.53
BXD87 m 4.2303 1.7639   5 0.78882 0.417 2.0311, 6.3617 -0.45
BXD89 m 5.1664 1.004   5 0.44901 0.1943 4.0533, 6.3781 -0.26
BXD90 m 9.981 1.4241   5 0.63687 0.1427 7.7792, 11.541 0.73
C57BL/6J m 12.592 2.6   5 1.1628 0.2065 9.1859, 15.192 1.26
DBA/2J m 8.262 2.7988   5 1.2517 0.3388 4.1685, 10.472 0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 8.3854 1.3068000179 10.9705621585 5.8002378415
BXD100 m 2.0018175 1.4610468365 4.8921166596 -0.8884816596
BXD12 m 2.1692 1.4610468365 5.0594991596 -0.7210991596
BXD27 m 9.1563166667 1.1929397466 11.5162360483 6.796397285
BXD32 m 5.3877 1.4610468365 8.2779991596 2.4974008404
BXD34 m 3.933625 1.4610468365 6.8239241596 1.0433258404
BXD39 m 2.95334 1.3068000179 5.5385021585 0.3681778415
BXD40 m 2.025194 1.3068000179 4.6103561585 -0.5599681585
BXD43 m 2.60254 1.3068000179 5.1877021585 0.0173778415
BXD45 m 5.09632 1.3068000179 7.6814821585 2.5111578415
BXD48 m 13.07858 1.3068000179 15.6637421585 10.4934178415
BXD48a m 5.79886 1.3068000179 8.3840221585 3.2136978415
BXD49 m 5.75732 1.3068000179 8.3424821585 3.1721578415
BXD51 m 3.7611 1.3068000179 6.3462621585 1.1759378415
BXD53 m 4.401274 1.3068000179 6.9864361585 1.8161118415
BXD55 m 6.53302 1.3068000179 9.1181821585 3.9478578415
BXD6 m 0.93667 2.0662322514 5.0241702708 -3.1508302708
BXD62 m 4.40272 1.3068000179 6.9878821585 1.8175578415
BXD63 m 10.64808 1.3068000179 13.2332421585 8.0629178415
BXD64 m 3.21404 1.3068000179 5.7992021585 0.6288778415
BXD66 m 2.9545 1.3068000179 5.5396621585 0.3693378415
BXD67 m 3.82464 1.3068000179 6.4098021585 1.2394778415
BXD69 m 14.07 1.3068000179 16.6551621585 11.4848378415
BXD73 m 6.60192 1.3068000179 9.1870821585 4.0167578415
BXD75 m 13.9084 1.3068000179 16.4935621585 11.3232378415
BXD77 m 5.75396 1.3068000179 8.3391221585 3.1687978415
BXD79 m 3.44072 1.3068000179 6.0258821585 0.8555578415
BXD8 m 2.158125 1.4610468365 5.0484241596 -0.7321741596
BXD81 m 25.466 1.3068000179 28.0511621585 22.8808378415
BXD84 m 9.0257666667 1.6870715687 12.3631966623 5.688336671
BXD87 m 4.23028 1.3068000179 6.8154421585 1.6451178415
BXD89 m 5.1664 1.3068000179 7.7515621585 2.5812378415
BXD90 m 9.98096 1.3068000179 12.5661221585 7.3957978415
C57BL/6J m 12.59198 1.3068000179 15.1771421585 10.0068178415
DBA/2J m 8.26202 1.3068000179 10.8471821585 5.6768578415




  GWAS USING LINEAR MIXED MODELS