Project measure / variable:   Schoonjans1   LCA_feces_CD

ID, description, units MPD:112782   LCA_feces_CD   bile acid 3-oxocholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid 3-oxocholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means2.3357   ng/mL
Median of the strain means2.1638   ng/mL
SD of the strain means± 1.1198
Coefficient of variation (CV)0.4794
Min–max range of strain means0.91612   –   5.1472   ng/mL
Mean sample size per strain4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 215.6227 6.3418 14.2528 < 0.0001
Residuals 134 59.6238 0.445


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.4894 0.29437   5 0.13165 0.1977 0.97577, 1.7158 -0.76
BXD100 m 1.7468 0.33371   5 0.14924 0.191 1.4193, 2.2492 -0.53
BXD11 m 1.6489 1.0667   4 0.53337 0.6469 1.0479, 3.2471 -0.61
BXD12 m 1.5819 0.15592   4 0.07796 0.0986 1.4038, 1.7634 -0.67
BXD27 m 1.4933 0.62267   4 0.31134 0.417 0.8363, 2.2246 -0.75
BXD32 m 2.6316 1.2298   4 0.61492 0.4673 0.94274, 3.8682 0.26
BXD34 m 1.6648 0.20426   4 0.10213 0.1227 1.3757, 1.8406 -0.6
BXD39 m 0.92698 0.34414   5 0.15391 0.3713 0.56985, 1.4286 -1.26
BXD40 m 0.96896 0.12153   5 0.05435 0.1254 0.81199, 1.1302 -1.22
BXD43 m 1.3135 0.25822   4 0.12911 0.1966 0.96557, 1.5598 -0.91
BXD45 m 2.8738 0.58517   3 0.33785 0.2036 2.5188, 3.5492 0.48
BXD48 m 2.948 0.87751   5 0.39244 0.2977 1.9224, 4.1143 0.55
BXD48a m 1.8977 0.25471   4 0.12736 0.1342 1.5716, 2.1334 -0.39
BXD49 m 2.6261 0.39324   5 0.17586 0.1497 2.1166, 3.1347 0.26
BXD51 m 1.7093 0.50677   5 0.22663 0.2965 1.1339, 2.431 -0.56
BXD53 m 0.94205 0.25989   5 0.11623 0.2759 0.51524, 1.1934 -1.24
BXD55 m 4.7596 1.2786   5 0.57181 0.2686 3.4295, 6.1783 2.16
BXD6 m 2.7881 0.0   1   0.0 0.0 2.7881, 2.7881 0.4
BXD62 m 1.2951 0.15421   5 0.06896 0.1191 1.135, 1.4865 -0.93
BXD63 m 3.7176 0.8679   5 0.38814 0.2335 2.5604, 4.8002 1.23
BXD64 m 1.3259 0.19085   5 0.08535 0.1439 1.0232, 1.5415 -0.9
BXD66 m 1.2754 0.26293   5 0.11759 0.2061 0.99418, 1.7035 -0.95
BXD67 m 0.91612 0.13621   4 0.06811 0.1487 0.74069, 1.0473 -1.27
BXD69 m 4.3598 0.77419   5 0.34623 0.1776 3.1735, 5.2611 1.81
BXD73 m 3.6239 0.89662   5 0.40098 0.2474 2.4404, 4.6908 1.15
BXD75 m 5.1472 0.86338   5 0.38612 0.1677 4.2381, 6.2168 2.51
BXD77 m 2.2709 0.25584   5 0.11442 0.1127 1.9999, 2.5908 -0.06
BXD79 m 2.5792 0.2085   5 0.09324 0.0808 2.3081, 2.7544 0.22
BXD8 m 1.2957 0.38806   5 0.17354 0.2995 0.92591, 1.8905 -0.93
BXD81 m 3.0257 0.86879   4 0.43439 0.2871 1.7462, 3.6852 0.62
BXD84 m 3.8977 1.1337   5 0.507 0.2909 3.1126, 5.881 1.39
BXD87 m 2.0567 0.27556   5 0.12323 0.134 1.7074, 2.4519 -0.25
BXD89 m 2.8498 0.71934   5 0.3217 0.2524 1.9421, 3.7303 0.46
BXD90 m 2.3522 0.23078   5 0.10321 0.0981 2.0165, 2.6292 0.01
C57BL/6J m 3.2301 0.56399   10 0.17835 0.1746 2.2985, 4.1514 0.8
DBA/2J m 2.8571 1.6045   5 0.71756 0.5616 1.5324, 5.1514 0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.489354 0.2983130808 2.0793652953 0.8993427047
BXD100 m 1.74684 0.2983130808 2.3368512953 1.1568287047
BXD11 m 1.648925 0.3335241637 2.3085776818 0.9892723182
BXD12 m 1.58195 0.3335241637 2.2416026818 0.9222973182
BXD27 m 1.493275 0.3335241637 2.1529276818 0.8336223182
BXD32 m 2.63161 0.3335241637 3.2912626818 1.9719573182
BXD34 m 1.664825 0.3335241637 2.3244776818 1.0051723182
BXD39 m 0.92698 0.2983130808 1.5169912953 0.3369687047
BXD40 m 0.968956 0.2983130808 1.5589672953 0.3789447047
BXD43 m 1.3135175 0.3335241637 1.9731701818 0.6538648182
BXD45 m 2.8738 0.3851205313 3.6355013069 2.1120986931
BXD48 m 2.94798 0.2983130808 3.5379912953 2.3579687047
BXD48a m 1.8977 0.3335241637 2.5573526818 1.2380473182
BXD49 m 2.62608 0.2983130808 3.2160912953 2.0360687047
BXD51 m 1.70932 0.2983130808 2.2993312953 1.1193087047
BXD53 m 0.942052 0.2983130808 1.5320632953 0.3520407047
BXD55 m 4.75962 0.2983130808 5.3496312953 4.1696087047
BXD62 m 1.29506 0.2983130808 1.8850712953 0.7050487047
BXD63 m 3.71758 0.2983130808 4.3075912953 3.1275687047
BXD64 m 1.32592 0.2983130808 1.9159312953 0.7359087047
BXD66 m 1.275436 0.2983130808 1.8654472953 0.6854247047
BXD67 m 0.91612 0.3335241637 1.5757726818 0.2564673182
BXD69 m 4.35982 0.2983130808 4.9498312953 3.7698087047
BXD73 m 3.62392 0.2983130808 4.2139312953 3.0339087047
BXD75 m 5.14716 0.2983130808 5.7371712953 4.5571487047
BXD77 m 2.27094 0.2983130808 2.8609512953 1.6809287047
BXD79 m 2.57918 0.2983130808 3.1691912953 1.9891687047
BXD8 m 1.295662 0.2983130808 1.8856732953 0.7056507047
BXD81 m 3.02575 0.3335241637 3.6854026818 2.3660973182
BXD84 m 3.8977 0.2983130808 4.4877112953 3.3076887047
BXD87 m 2.05674 0.2983130808 2.6467512953 1.4667287047
BXD89 m 2.84976 0.2983130808 3.4397712953 2.2597487047
BXD90 m 2.35216 0.2983130808 2.9421712953 1.7621487047
C57BL/6J m 3.23013 0.2109392024 3.6473309879 2.8129290121
DBA/2J m 2.85706 0.2983130808 3.4470712953 2.2670487047




  GWAS USING LINEAR MIXED MODELS