Project measure / variable:   Schoonjans1   DCA_feces_HFD

ID, description, units MPD:112769   DCA_feces_HFD   bile acid deoxycholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid deoxycholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means59.99   ng/mL
Median of the strain means36.326   ng/mL
SD of the strain means± 55.08
Coefficient of variation (CV)0.9182
Min–max range of strain means2.5632   –   175.0   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 505806.7123 14451.6204 18.7081 < 0.0001
Residuals 136 105057.298 772.4801


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 150.4 42.898   5 19.185 0.2853 86.61, 206.0 1.64
BXD100 m 13.925 4.4091   4 2.2046 0.3166 9.2782, 18.627 -0.84
BXD11 m 2.7668 4.6472   3 2.6831 1.6797 0.06928, 8.1329 -1.04
BXD12 m 10.288 5.1935   4 2.5968 0.5048 2.9454, 14.469 -0.9
BXD27 m 64.15 78.99   6 32.25 1.2313 9.1261, 197.2 0.08
BXD32 m 44.044 15.706   4 7.8532 0.3566 24.05, 61.17 -0.29
BXD34 m 34.566 8.2869   4 4.1434 0.2397 29.566, 46.946 -0.46
BXD39 m 23.1 10.287   5 4.6004 0.4453 11.467, 36.879 -0.67
BXD40 m 11.766 4.7767   5 2.1362 0.406 4.9045, 18.05 -0.88
BXD43 m 20.974 4.5812   5 2.0488 0.2184 16.968, 28.522 -0.71
BXD45 m 23.15 11.548   5 5.1645 0.4988 9.99, 40.403 -0.67
BXD48 m 158.7 77.56   5 34.685 0.4887 71.07, 282.8 1.79
BXD48a m 46.165 14.181   5 6.3418 0.3072 24.378, 60.24 -0.25
BXD49 m 62.88 19.971   5 8.9313 0.3176 36.579, 83.03 0.05
BXD51 m 68.61 13.575   5 6.071 0.1979 50.15, 84.0 0.16
BXD53 m 29.982 17.149   5 7.6692 0.572 4.0918, 50.35 -0.54
BXD55 m 38.086 5.5852   5 2.4978 0.1466 31.17, 44.856 -0.4
BXD6 m 2.5632 3.3459   5 1.4963 1.3054 0.09284, 6.7882 -1.04
BXD62 m 33.295 14.733   5 6.589 0.4425 14.27, 55.62 -0.48
BXD63 m 175.0 42.026   5 18.795 0.2401 132.6, 231.5 2.09
BXD64 m 11.906 4.5912   5 2.0532 0.3856 4.6311, 16.921 -0.87
BXD66 m 18.955 8.3887   5 3.7515 0.4426 12.261, 33.493 -0.75
BXD67 m 24.312 10.11   5 4.5213 0.4158 12.538, 36.272 -0.65
BXD69 m 163.7 29.791   5 13.323 0.1819 141.8, 210.2 1.88
BXD73 m 30.652 23.071   5 10.318 0.7527 11.73, 69.7 -0.53
BXD75 m 122.5 45.993   5 20.568 0.3755 53.19, 177.4 1.13
BXD77 m 54.92 22.347   5 9.9938 0.4069 28.168, 84.3 -0.09
BXD79 m 23.333 13.644   5 6.1017 0.5847 12.542, 45.794 -0.67
BXD8 m 10.537 4.4218   4 2.2109 0.4197 4.6764, 15.248 -0.9
BXD81 m 169.9 32.136   5 14.372 0.1892 120.5, 208.3 2.0
BXD84 m 132.6 17.992   3 10.388 0.1357 118.0, 152.7 1.32
BXD87 m 63.72 19.405   5 8.6784 0.3046 45.853, 89.64 0.07
BXD89 m 33.419 8.1281   5 3.635 0.2432 26.134, 45.391 -0.48
BXD90 m 50.69 12.831   5 5.7383 0.2531 32.723, 65.62 -0.17
C57BL/6J m 165.8 16.138   5 7.2173 0.0973 150.9, 188.5 1.92
DBA/2J m 68.35 21.171   5 9.4679 0.3097 40.732, 93.29 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 150.362 12.4296430538 174.9423745699 125.7816254301
BXD100 m 13.92455 13.8967634022 41.4062442253 -13.5571442253
BXD11 m 2.7667766667 16.0466001823 34.4999037842 -28.9663504509
BXD12 m 10.2876 13.8967634022 37.7692942253 -17.1940942253
BXD27 m 64.15435 11.3466598039 86.5930593731 41.7156406269
BXD32 m 44.0445 13.8967634022 71.5261942253 16.5628057747
BXD34 m 34.56625 13.8967634022 62.0479442253 7.0845557747
BXD39 m 23.1004 12.4296430538 47.6807745699 -1.4799745699
BXD40 m 11.7661 12.4296430538 36.3464745699 -12.8142745699
BXD43 m 20.9744 12.4296430538 45.5547745699 -3.6059745699
BXD45 m 23.1498 12.4296430538 47.7301745699 -1.4305745699
BXD48 m 158.714 12.4296430538 183.2943745699 134.1336254301
BXD48a m 46.1654 12.4296430538 70.7457745699 21.5850254301
BXD49 m 62.8762 12.4296430538 87.4565745699 38.2958254301
BXD51 m 68.606 12.4296430538 93.1863745699 44.0256254301
BXD53 m 29.98216 12.4296430538 54.5625345699 5.4017854301
BXD55 m 38.0856 12.4296430538 62.6659745699 13.5052254301
BXD6 m 2.563246 12.4296430538 27.1436205699 -22.0171285699
BXD62 m 33.295 12.4296430538 57.8753745699 8.7146254301
BXD63 m 175.04 12.4296430538 199.6203745699 150.4596254301
BXD64 m 11.90602 12.4296430538 36.4863945699 -12.6743545699
BXD66 m 18.955 12.4296430538 43.5353745699 -5.6253745699
BXD67 m 24.3118 12.4296430538 48.8921745699 -0.2685745699
BXD69 m 163.74 12.4296430538 188.3203745699 139.1596254301
BXD73 m 30.6524 12.4296430538 55.2327745699 6.0720254301
BXD75 m 122.478 12.4296430538 147.0583745699 97.8976254301
BXD77 m 54.924 12.4296430538 79.5043745699 30.3436254301
BXD79 m 23.3332 12.4296430538 47.9135745699 -1.2471745699
BXD8 m 10.5366 13.8967634022 38.0182942253 -16.9450942253
BXD81 m 169.86 12.4296430538 194.4403745699 145.2796254301
BXD84 m 132.6 16.0466001823 164.3331271175 100.8668728825
BXD87 m 63.7152 12.4296430538 88.2955745699 39.1348254301
BXD89 m 33.4192 12.4296430538 57.9995745699 8.8388254301
BXD90 m 50.692 12.4296430538 75.2723745699 26.1116254301
C57BL/6J m 165.8 12.4296430538 190.3803745699 141.2196254301
DBA/2J m 68.3544 12.4296430538 92.9347745699 43.7740254301




  GWAS USING LINEAR MIXED MODELS