Project measure / variable:   Schoonjans1   CDCA_feces_HFD

ID, description, units MPD:112767   CDCA_feces_HFD   bile acid chenodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid chenodeoxycholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.73814   ng/mL
Median of the strain means0.43907   ng/mL
SD of the strain means± 0.74255
Coefficient of variation (CV)1.006
Min–max range of strain means0.13176   –   3.7476   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 95.5308 2.7295 4.3926 < 0.0001
Residuals 136 84.5066 0.6214


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.65584 0.24615   5 0.11008 0.3753 0.45499, 1.0288 -0.11
BXD100 m 0.14182 0.03353   4 0.01676 0.2364 0.11511, 0.1893 -0.8
BXD11 m 0.31827 0.15629   3 0.09024 0.4911 0.19269, 0.49331 -0.57
BXD12 m 0.4021 0.35183   4 0.17592 0.875 0.14237, 0.91637 -0.45
BXD27 m 1.6383 2.3387   6 0.95478 1.4275 0.19341, 6.1936 1.21
BXD32 m 0.6982 0.25765   4 0.12883 0.369 0.54191, 1.0804 -0.05
BXD34 m 0.87078 0.17253   4 0.08627 0.1981 0.75376, 1.1267 0.18
BXD39 m 0.39454 0.17956   5 0.0803 0.4551 0.22153, 0.68948 -0.46
BXD40 m 0.32534 0.25111   5 0.1123 0.7718 0.10478, 0.7188 -0.56
BXD43 m 0.37438 0.16237   5 0.07262 0.4337 0.15709, 0.53118 -0.49
BXD45 m 0.51471 0.38352   5 0.17152 0.7451 0.15685, 1.114 -0.3
BXD48 m 3.7476 2.4217   5 1.083 0.6462 0.64957, 6.4668 4.05
BXD48a m 0.90886 0.64985   5 0.29062 0.715 0.32333, 1.9949 0.23
BXD49 m 0.15418 0.11342   5 0.05072 0.7356 0.07441, 0.35402 -0.79
BXD51 m 1.7725 0.71011   5 0.31757 0.4006 0.80595, 2.7562 1.39
BXD53 m 0.4931 0.42177   5 0.18862 0.8553 0.05548, 1.1513 -0.33
BXD55 m 0.66078 0.17744   5 0.07935 0.2685 0.39161, 0.84154 -0.1
BXD6 m 0.16688 0.11005   5 0.04922 0.6595 0.05335, 0.2886 -0.77
BXD62 m 0.364 0.2681   5 0.1199 0.7365 0.06218, 0.69893 -0.5
BXD63 m 0.3628 0.17739   5 0.07933 0.4889 0.21024, 0.64646 -0.51
BXD64 m 0.13176 0.06665   5 0.02981 0.5058 0.05232, 0.19742 -0.82
BXD66 m 0.39532 0.23617   5 0.10562 0.5974 0.1949, 0.77514 -0.46
BXD67 m 0.36381 0.27437   5 0.1227 0.7542 0.07289, 0.68625 -0.5
BXD69 m 0.70782 0.39416   5 0.17627 0.5569 0.27537, 1.1618 -0.04
BXD73 m 0.40847 0.24963   5 0.11164 0.6111 0.14269, 0.79157 -0.44
BXD75 m 1.416 1.0367   5 0.46361 0.7321 0.31159, 2.9166 0.91
BXD77 m 2.565 1.6649   5 0.74456 0.6491 0.50473, 4.4904 2.46
BXD79 m 0.21326 0.12285   5 0.05494 0.5761 0.0485, 0.34552 -0.71
BXD8 m 0.15741 0.03753   4 0.01876 0.2384 0.12719, 0.21165 -0.78
BXD81 m 1.0789 1.0521   5 0.47053 0.9752 0.2846, 2.3194 0.46
BXD84 m 0.24115 0.08375   3 0.04835 0.3473 0.14622, 0.3046 -0.67
BXD87 m 0.73136 0.68753   5 0.30747 0.9401 0.1839, 1.8485 -0.01
BXD89 m 0.37102 0.12519   5 0.05599 0.3374 0.22983, 0.57158 -0.49
BXD90 m 1.3709 0.80899   5 0.36179 0.5901 0.81236, 2.7664 0.85
C57BL/6J m 0.98615 0.3586   5 0.16037 0.3636 0.43038, 1.2694 0.33
DBA/2J m 0.46966 0.23556   5 0.10534 0.5015 0.17755, 0.76048 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.655836 0.3525256998 1.3529769966 -0.0413049966
BXD100 m 0.1418225 0.3941357142 0.9212498291 -0.6376048291
BXD11 m 0.31827 0.4551087214 1.2182751566 -0.5817351566
BXD12 m 0.4020975 0.3941357142 1.1815248291 -0.3773298291
BXD27 m 1.6382933333 0.3218104631 2.2746930826 1.001893584
BXD32 m 0.6982 0.3941357142 1.4776273291 -0.0812273291
BXD34 m 0.8707775 0.3941357142 1.6502048291 0.0913501709
BXD39 m 0.39454 0.3525256998 1.0916809966 -0.3026009966
BXD40 m 0.325336 0.3525256998 1.0224769966 -0.3718049966
BXD43 m 0.374376 0.3525256998 1.0715169966 -0.3227649966
BXD45 m 0.514712 0.3525256998 1.2118529966 -0.1824289966
BXD48 m 3.747574 0.3525256998 4.4447149966 3.0504330034
BXD48a m 0.908858 0.3525256998 1.6059989966 0.2117170034
BXD49 m 0.154176 0.3525256998 0.8513169966 -0.5429649966
BXD51 m 1.77251 0.3525256998 2.4696509966 1.0753690034
BXD53 m 0.493096 0.3525256998 1.1902369966 -0.2040449966
BXD55 m 0.660782 0.3525256998 1.3579229966 -0.0363589966
BXD6 m 0.166876 0.3525256998 0.8640169966 -0.5302649966
BXD62 m 0.364004 0.3525256998 1.0611449966 -0.3331369966
BXD63 m 0.362804 0.3525256998 1.0599449966 -0.3343369966
BXD64 m 0.131758 0.3525256998 0.8288989966 -0.5653829966
BXD66 m 0.395324 0.3525256998 1.0924649966 -0.3018169966
BXD67 m 0.363814 0.3525256998 1.0609549966 -0.3333269966
BXD69 m 0.707824 0.3525256998 1.4049649966 0.0106830034
BXD73 m 0.40847 0.3525256998 1.1056109966 -0.2886709966
BXD75 m 1.416034 0.3525256998 2.1131749966 0.7188930034
BXD77 m 2.565026 0.3525256998 3.2621669966 1.8678850034
BXD79 m 0.213262 0.3525256998 0.9104029966 -0.4838789966
BXD8 m 0.157415 0.3941357142 0.9368423291 -0.6220123291
BXD81 m 1.078904 0.3525256998 1.7760449966 0.3817630034
BXD84 m 0.2411533333 0.4551087214 1.1411584899 -0.6588518232
BXD87 m 0.731364 0.3525256998 1.4285049966 0.0342230034
BXD89 m 0.37102 0.3525256998 1.0681609966 -0.3261209966
BXD90 m 1.370946 0.3525256998 2.0680869966 0.6738050034
C57BL/6J m 0.986152 0.3525256998 1.6832929966 0.2890110034
DBA/2J m 0.469662 0.3525256998 1.1668029966 -0.2274789966




  GWAS USING LINEAR MIXED MODELS