Project measure / variable:   Schoonjans1   CA_feces_HFD

ID, description, units MPD:112765   CA_feces_HFD   bile acid cholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid cholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means21.183   ng/mL
Median of the strain means12.502   ng/mL
SD of the strain means± 22.367
Coefficient of variation (CV)1.0559
Min–max range of strain means3.7454   –   113.4   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 86232.8484 2463.7957 6.6652 < 0.0001
Residuals 136 50272.8339 369.6532


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 44.909 18.349   5 8.206 0.4086 28.259, 70.9 1.06
BXD100 m 9.3262 1.4174   4 0.70871 0.152 8.3881, 11.418 -0.53
BXD11 m 16.009 15.142   3 8.742 0.9458 1.4553, 31.677 -0.23
BXD12 m 5.8498 3.7712   4 1.8856 0.6447 0.68268, 9.74 -0.69
BXD27 m 17.808 17.062   6 6.9655 0.9581 5.5627, 51.08 -0.15
BXD32 m 14.85 9.4483   4 4.7242 0.6363 9.9514, 29.021 -0.28
BXD34 m 28.717 5.2937   4 2.6468 0.1843 25.899, 36.655 0.34
BXD39 m 5.7219 4.0634   5 1.8172 0.7102 2.5887, 12.763 -0.69
BXD40 m 9.6903 4.8425   5 2.1656 0.4997 3.3555, 16.83 -0.51
BXD43 m 15.328 4.9791   5 2.2267 0.3248 9.6291, 22.125 -0.26
BXD45 m 10.84 8.965   5 4.0093 0.827 4.3679, 25.605 -0.46
BXD48 m 113.4 74.49   5 33.315 0.6568 24.289, 184.4 4.12
BXD48a m 31.664 17.956   5 8.0302 0.5671 6.1031, 52.84 0.47
BXD49 m 11.647 7.4385   5 3.3266 0.6387 3.1166, 23.441 -0.43
BXD51 m 73.73 34.069   5 15.236 0.4621 30.083, 109.7 2.35
BXD53 m 11.543 12.704   5 5.6813 1.1005 1.3302, 32.689 -0.43
BXD55 m 9.7865 3.7053   5 1.6571 0.3786 4.1248, 13.132 -0.51
BXD6 m 10.06 7.8517   5 3.5114 0.7805 2.6735, 19.261 -0.5
BXD62 m 5.2831 4.4555   5 1.9925 0.8433 0.98499, 12.498 -0.71
BXD63 m 13.357 4.7843   5 2.1396 0.3582 8.8789, 21.125 -0.35
BXD64 m 5.8762 2.1842   5 0.97681 0.3717 3.0928, 8.6955 -0.68
BXD66 m 19.842 9.6007   5 4.2936 0.4839 10.056, 29.489 -0.06
BXD67 m 11.523 6.557   5 2.9324 0.569 4.2971, 21.668 -0.43
BXD69 m 14.585 16.216   5 7.2521 1.1118 2.9418, 42.54 -0.29
BXD73 m 8.3344 3.1372   5 1.403 0.3764 2.9986, 11.215 -0.57
BXD75 m 38.972 28.77   5 12.866 0.7382 4.731, 77.27 0.8
BXD77 m 65.13 38.016   5 17.001 0.5837 19.852, 106.9 1.96
BXD79 m 9.9497 6.3651   5 2.8465 0.6397 0.37231, 16.595 -0.5
BXD8 m 7.9194 3.7531   4 1.8765 0.4739 2.4577, 11.009 -0.59
BXD81 m 17.204 25.989   5 11.623 1.5106 1.4366, 62.31 -0.18
BXD84 m 3.7454 2.3793   3 1.3737 0.6353 1.836, 6.4109 -0.78
BXD87 m 28.927 15.916   5 7.1177 0.5502 11.585, 52.7 0.35
BXD89 m 10.789 3.2706   5 1.4626 0.3031 5.5171, 14.007 -0.46
BXD90 m 24.964 8.7094   5 3.895 0.3489 16.85, 39.457 0.17
C57BL/6J m 27.194 18.933   5 8.4673 0.6962 4.0237, 42.781 0.27
DBA/2J m 8.112 5.2101   5 2.33 0.6423 3.1166, 13.903 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 44.909 8.5982927406 61.9126464692 27.9053535308
BXD100 m 9.3262 9.6131835292 28.3368546852 -9.6844546852
BXD11 m 16.0087666667 11.1003481967 37.9603798666 -5.9428465333
BXD12 m 5.849795 9.6131835292 24.8604496852 -13.1608596852
BXD27 m 17.80765 7.8491314834 33.3297845517 2.2855154483
BXD32 m 14.84985 9.6131835292 33.8605046852 -4.1608046852
BXD34 m 28.71675 9.6131835292 47.7274046852 9.7060953148
BXD39 m 5.72186 8.5982927406 22.7255064692 -11.2817864692
BXD40 m 9.69028 8.5982927406 26.6939264692 -7.3133664692
BXD43 m 15.32822 8.5982927406 32.3318664692 -1.6754264692
BXD45 m 10.8398 8.5982927406 27.8434464692 -6.1638464692
BXD48 m 113.4236 8.5982927406 130.4272464692 96.4199535308
BXD48a m 31.66382 8.5982927406 48.6674664692 14.6601735308
BXD49 m 11.64662 8.5982927406 28.6502664692 -5.3570264692
BXD51 m 73.7306 8.5982927406 90.7342464692 56.7269535308
BXD53 m 11.54342 8.5982927406 28.5470664692 -5.4602264692
BXD55 m 9.78652 8.5982927406 26.7901664692 -7.2171264692
BXD6 m 10.06028 8.5982927406 27.0639264692 -6.9433664692
BXD62 m 5.283098 8.5982927406 22.2867444692 -11.7205484692
BXD63 m 13.35678 8.5982927406 30.3604264692 -3.6468664692
BXD64 m 5.8762 8.5982927406 22.8798464692 -11.1274464692
BXD66 m 19.842 8.5982927406 36.8456464692 2.8383535308
BXD67 m 11.52316 8.5982927406 28.5268064692 -5.4804864692
BXD69 m 14.58508 8.5982927406 31.5887264692 -2.4185664692
BXD73 m 8.3344 8.5982927406 25.3380464692 -8.6692464692
BXD75 m 38.9722 8.5982927406 55.9758464692 21.9685535308
BXD77 m 65.1288 8.5982927406 82.1324464692 48.1251535308
BXD79 m 9.949682 8.5982927406 26.9533284692 -7.0539644692
BXD8 m 7.919425 9.6131835292 26.9300796852 -11.0912296852
BXD81 m 17.20402 8.5982927406 34.2076664692 0.2003735308
BXD84 m 3.7453666667 11.1003481967 25.6969798666 -18.2062465333
BXD87 m 28.927 8.5982927406 45.9306464692 11.9233535308
BXD89 m 10.78882 8.5982927406 27.7924664692 -6.2148264692
BXD90 m 24.9644 8.5982927406 41.9680464692 7.9607535308
C57BL/6J m 27.19356 8.5982927406 44.1972064692 10.1899135308
DBA/2J m 8.112 8.5982927406 25.1156464692 -8.8916464692




  GWAS USING LINEAR MIXED MODELS