Project measure / variable:   Schoonjans1   CA_feces_CD

ID, description, units MPD:112764   CA_feces_CD   bile acid cholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid cholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means3.7739   ng/mL
Median of the strain means2.8362   ng/mL
SD of the strain means± 3.1968
Coefficient of variation (CV)0.8471
Min–max range of strain means0.26421   –   16.923   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1795.3937 51.297 4.2891 < 0.0001
Residuals 139 1662.4274 11.9599


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.8866 2.2259   5 0.99545 0.5727 1.8685, 7.5694 0.04
BXD100 m 5.7975 1.3925   5 0.62275 0.2402 4.3729, 7.6168 0.63
BXD11 m 5.8053 4.0795   4 2.0397 0.7027 2.1151, 11.502 0.64
BXD12 m 2.1805 1.3474   4 0.67371 0.6179 1.3561, 4.1951 -0.5
BXD27 m 3.6289 0.72788   4 0.36394 0.2006 2.8407, 4.4141 -0.05
BXD32 m 3.2831 3.7917   4 1.8959 1.1549 1.1078, 8.9508 -0.15
BXD34 m 0.94846 0.1301   4 0.06505 0.1372 0.76145, 1.0593 -0.88
BXD39 m 1.5808 0.9595   5 0.4291 0.607 0.84844, 3.242 -0.69
BXD40 m 1.7552 0.41491   5 0.18556 0.2364 1.1442, 2.2806 -0.63
BXD43 m 5.6769 3.0458   4 1.5229 0.5365 2.1394, 9.0821 0.6
BXD45 m 0.75423 0.53767   3 0.31043 0.7129 0.30654, 1.3506 -0.94
BXD48 m 7.0079 7.682   5 3.4355 1.0962 2.0685, 20.322 1.01
BXD48a m 5.1603 2.9368   4 1.4684 0.5691 2.5153, 9.2985 0.43
BXD49 m 0.94988 0.21769   5 0.09735 0.2292 0.75804, 1.2935 -0.88
BXD51 m 6.0583 3.6092   5 1.6141 0.5957 1.9482, 10.835 0.71
BXD53 m 0.26421 0.06667   5 0.02982 0.2523 0.15087, 0.31494 -1.1
BXD55 m 1.3752 0.56614   5 0.25319 0.4117 0.956, 2.3093 -0.75
BXD6 m 8.6639 4.7295   5 2.1151 0.5459 1.5027, 13.707 1.53
BXD62 m 3.8272 2.2428   5 1.003 0.586 0.95388, 6.4721 0.02
BXD63 m 1.2462 1.4491   5 0.64804 1.1628 0.4082, 3.8218 -0.79
BXD64 m 2.5763 0.70257   5 0.3142 0.2727 1.7256, 3.5426 -0.37
BXD66 m 6.6067 2.1724   5 0.97155 0.3288 3.681, 9.654 0.89
BXD67 m 3.231 0.56076   4 0.28038 0.1736 2.5305, 3.8077 -0.17
BXD69 m 1.3963 0.96752   5 0.43269 0.6929 0.61489, 2.7002 -0.74
BXD73 m 1.7137 1.5209   5 0.68019 0.8875 0.47107, 4.196 -0.64
BXD75 m 2.5956 2.1134   5 0.94515 0.8142 0.73545, 5.3525 -0.37
BXD77 m 8.1815 3.5369   5 1.5817 0.4323 3.4976, 12.504 1.38
BXD79 m 2.6245 1.5037   5 0.67246 0.5729 0.89348, 4.9717 -0.36
BXD8 m 2.4142 0.84765   5 0.37908 0.3511 1.6542, 3.7655 -0.43
BXD81 m 2.9891 3.2397   5 1.4488 1.0838 0.94159, 8.695 -0.25
BXD84 m 0.56743 0.19331   5 0.08645 0.3407 0.38045, 0.83847 -1.0
BXD87 m 2.6833 1.3821   5 0.61809 0.5151 1.2597, 4.8621 -0.34
BXD89 m 5.4501 3.152   5 1.4096 0.5783 2.5907, 10.665 0.52
BXD90 m 16.923 14.354   5 6.4193 0.8482 5.4642, 40.05 4.11
C57BL/6J m 0.73051 0.47696   10 0.15083 0.6529 0.33202, 1.9328 -0.95
DBA/2J m 5.3251 3.0861   5 1.3801 0.5795 1.4675, 9.0898 0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.88662 1.5466033165 6.9445296261 0.8287103739
BXD100 m 5.79752 1.5466033165 8.8554296261 2.7396103739
BXD11 m 5.8053 1.729155075 9.2241468965 2.3864531035
BXD12 m 2.1805 1.729155075 5.5993468965 -1.2383468965
BXD27 m 3.62885 1.729155075 7.0476968965 0.2100031035
BXD32 m 3.2831 1.729155075 6.7019468965 -0.1357468965
BXD34 m 0.94846 1.729155075 4.3673068965 -2.4703868965
BXD39 m 1.580788 1.5466033165 4.6386976261 -1.4771216261
BXD40 m 1.75518 1.5466033165 4.8130896261 -1.3027296261
BXD43 m 5.676925 1.729155075 9.0957718965 2.2580781035
BXD45 m 0.7542333333 1.996656296 4.7019776853 -3.1935110187
BXD48 m 7.00794 1.5466033165 10.0658496261 3.9500303739
BXD48a m 5.160325 1.729155075 8.5791718965 1.7414781035
BXD49 m 0.949878 1.5466033165 4.0077876261 -2.1080316261
BXD51 m 6.05828 1.5466033165 9.1161896261 3.0003703739
BXD53 m 0.264206 1.5466033165 3.3221156261 -2.7937036261
BXD55 m 1.375174 1.5466033165 4.4330836261 -1.6827356261
BXD6 m 8.66392 1.5466033165 11.7218296261 5.6060103739
BXD62 m 3.827176 1.5466033165 6.8850856261 0.7692663739
BXD63 m 1.24619 1.5466033165 4.3040996261 -1.8117196261
BXD64 m 2.5763 1.5466033165 5.6342096261 -0.4816096261
BXD66 m 6.6067 1.5466033165 9.6646096261 3.5487903739
BXD67 m 3.231025 1.729155075 6.6498718965 -0.1878218965
BXD69 m 1.396272 1.5466033165 4.4541816261 -1.6616376261
BXD73 m 1.713658 1.5466033165 4.7715676261 -1.3442516261
BXD75 m 2.595562 1.5466033165 5.6534716261 -0.4623476261
BXD77 m 8.18148 1.5466033165 11.2393896261 5.1235703739
BXD79 m 2.624516 1.5466033165 5.6824256261 -0.4333936261
BXD8 m 2.41422 1.5466033165 5.4721296261 -0.6436896261
BXD81 m 2.989118 1.5466033165 6.0470276261 -0.0687916261
BXD84 m 0.567434 1.5466033165 3.6253436261 -2.4904756261
BXD87 m 2.68328 1.5466033165 5.7411896261 -0.3746296261
BXD89 m 5.45008 1.5466033165 8.5079896261 2.3921703739
BXD90 m 16.92338 1.5466033165 19.9812896261 13.8654703739
C57BL/6J m 0.730506 1.0936136929 2.8927746329 -1.4317626329
DBA/2J m 5.32512 1.5466033165 8.3830296261 2.2672103739




  GWAS USING LINEAR MIXED MODELS