Project measure / variable:   Schoonjans1   bMCA_feces_HFD

ID, description, units MPD:112763   bMCA_feces_HFD   bile acid β-muricholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid β-muricholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means27.181   ng/mL
Median of the strain means21.055   ng/mL
SD of the strain means± 16.879
Coefficient of variation (CV)0.621
Min–max range of strain means5.7169   –   74.25   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 48274.9668 1379.2848 6.9926 < 0.0001
Residuals 136 26825.7723 197.2483


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 52.62 12.617   5 5.6423 0.2398 38.253, 71.08 1.51
BXD100 m 17.906 4.9582   4 2.4791 0.2769 12.342, 22.628 -0.55
BXD11 m 24.79 33.005   3 19.055 1.3314 3.1658, 62.78 -0.14
BXD12 m 12.738 10.2   4 5.0999 0.8007 1.314, 24.347 -0.86
BXD27 m 53.28 20.817   6 8.4987 0.3907 30.385, 86.83 1.55
BXD32 m 68.9 32.012   4 16.006 0.4646 32.905, 108.2 2.47
BXD34 m 37.349 6.0933   4 3.0467 0.1631 30.57, 45.352 0.6
BXD39 m 5.7169 1.6831   5 0.7527 0.2944 4.3854, 8.3278 -1.27
BXD40 m 11.413 5.605   5 2.5066 0.4911 4.7961, 19.93 -0.93
BXD43 m 20.833 7.0631   5 3.1587 0.339 10.617, 28.04 -0.38
BXD45 m 20.616 10.154   5 4.5411 0.4926 11.23, 37.659 -0.39
BXD48 m 38.451 14.353   5 6.4189 0.3733 26.695, 61.88 0.67
BXD48a m 22.309 6.2753   5 2.8064 0.2813 15.834, 30.923 -0.29
BXD49 m 20.171 12.39   5 5.5411 0.6143 8.0306, 37.024 -0.42
BXD51 m 74.25 15.282   5 6.8344 0.2058 52.86, 93.66 2.79
BXD53 m 7.232 4.8937   5 2.1885 0.6767 0.66074, 14.387 -1.18
BXD55 m 24.243 5.6141   5 2.5107 0.2316 17.889, 32.257 -0.17
BXD6 m 15.023 13.587   5 6.0764 0.9044 4.7075, 36.777 -0.72
BXD62 m 31.296 24.344   5 10.887 0.7779 10.418, 70.82 0.24
BXD63 m 34.606 12.842   5 5.7431 0.3711 20.122, 50.25 0.44
BXD64 m 5.761 2.5948   5 1.1604 0.4504 3.4878, 10.073 -1.27
BXD66 m 17.723 9.7876   5 4.3772 0.5523 7.3891, 31.353 -0.56
BXD67 m 12.735 6.3473   5 2.8386 0.4984 3.1198, 19.275 -0.86
BXD69 m 18.884 7.5491   5 3.376 0.3998 10.405, 27.295 -0.49
BXD73 m 18.127 7.4106   5 3.3141 0.4088 5.8311, 23.683 -0.54
BXD75 m 52.8 29.854   5 13.351 0.5654 13.689, 76.11 1.52
BXD77 m 32.14 17.932   5 8.0194 0.5579 13.174, 52.35 0.29
BXD79 m 10.339 3.7091   5 1.6588 0.3588 5.7772, 14.804 -1.0
BXD8 m 21.142 14.281   4 7.1404 0.6755 5.0328, 37.563 -0.36
BXD81 m 20.481 9.8759   5 4.4166 0.4822 11.882, 37.418 -0.4
BXD84 m 20.968 12.142   3 7.0099 0.5791 13.85, 34.987 -0.37
BXD87 m 40.277 15.033   5 6.7231 0.3732 25.965, 61.31 0.78
BXD89 m 14.757 6.2886   5 2.8124 0.4261 6.5353, 23.39 -0.74
BXD90 m 30.514 11.254   5 5.0328 0.3688 23.593, 50.41 0.2
C57BL/6J m 23.086 8.6775   5 3.8807 0.3759 13.456, 31.81 -0.24
DBA/2J m 45.03 21.855   5 9.774 0.4854 19.891, 79.69 1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 52.6194 6.2808968423 65.040255237 40.198544763
BXD100 m 17.90575 7.0222561496 31.7926883244 4.0188116756
BXD11 m 24.7904 8.1086029566 40.8256551596 8.7551448404
BXD12 m 12.738125 7.0222561496 26.6250633244 -1.1488133244
BXD27 m 53.2833333333 5.7336481365 64.6219709947 41.9446956719
BXD32 m 68.90375 7.0222561496 82.7906883244 55.0168116756
BXD34 m 37.3485 7.0222561496 51.2354383244 23.4615616756
BXD39 m 5.71692 6.2808968423 18.137775237 -6.703935237
BXD40 m 11.41344 6.2808968423 23.834295237 -1.007415237
BXD43 m 20.8328 6.2808968423 33.253655237 8.411944763
BXD45 m 20.6156 6.2808968423 33.036455237 8.194744763
BXD48 m 38.4514 6.2808968423 50.872255237 26.030544763
BXD48a m 22.3092 6.2808968423 34.730055237 9.888344763
BXD49 m 20.17074 6.2808968423 32.591595237 7.749884763
BXD51 m 74.248 6.2808968423 86.668855237 61.827144763
BXD53 m 7.231968 6.2808968423 19.652823237 -5.188887237
BXD55 m 24.2428 6.2808968423 36.663655237 11.821944763
BXD6 m 15.02326 6.2808968423 27.444115237 2.602404763
BXD62 m 31.2964 6.2808968423 43.717255237 18.875544763
BXD63 m 34.606 6.2808968423 47.026855237 22.185144763
BXD64 m 5.76098 6.2808968423 18.181835237 -6.659875237
BXD66 m 17.72302 6.2808968423 30.143875237 5.302164763
BXD67 m 12.73516 6.2808968423 25.156015237 0.314304763
BXD69 m 18.8838 6.2808968423 31.304655237 6.462944763
BXD73 m 18.12662 6.2808968423 30.547475237 5.705764763
BXD75 m 52.8006 6.2808968423 65.221455237 40.379744763
BXD77 m 32.1402 6.2808968423 44.561055237 19.719344763
BXD79 m 10.3387 6.2808968423 22.759555237 -2.082155237
BXD8 m 21.14245 7.0222561496 35.0293883244 7.2555116756
BXD81 m 20.4808 6.2808968423 32.901655237 8.059944763
BXD84 m 20.9676666667 8.1086029566 37.0029218262 4.9324115071
BXD87 m 40.2774 6.2808968423 52.698255237 27.856544763
BXD89 m 14.75746 6.2808968423 27.178315237 2.336604763
BXD90 m 30.5142 6.2808968423 42.935055237 18.093344763
C57BL/6J m 23.0862 6.2808968423 35.507055237 10.665344763
DBA/2J m 45.0296 6.2808968423 57.450455237 32.608744763




  GWAS USING LINEAR MIXED MODELS