Project measure / variable:   Schoonjans1   keto_DCA_feces_CD

ID, description, units MPD:112756   keto_DCA_feces_CD   bile acid 7-ketodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid 7-ketodeoxycholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.78847   ng/mL
Median of the strain means0.50268   ng/mL
SD of the strain means± 0.90329
Coefficient of variation (CV)1.1456
Min–max range of strain means0.03769   –   4.6012   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 139.5987 3.9885 4.2478 < 0.0001
Residuals 139 130.517 0.939


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.3316 0.35914   5 0.16061 0.2697 0.91323, 1.6388 0.6
BXD100 m 1.1887 0.57393   5 0.25667 0.4828 0.63983, 2.0252 0.44
BXD11 m 0.4467 0.39155   4 0.19577 0.8765 0.02699, 0.95486 -0.38
BXD12 m 0.1605 0.0716   4 0.0358 0.4461 0.12307, 0.26788 -0.7
BXD27 m 0.52014 0.23522   4 0.11761 0.4522 0.24974, 0.7776 -0.3
BXD32 m 0.42551 0.41236   4 0.20618 0.9691 0.17043, 1.0413 -0.4
BXD34 m 0.03769 0.01269   4 0.00634404 0.3367 0.0245, 0.0531 -0.83
BXD39 m 0.24706 0.13923   5 0.06226 0.5635 0.1137, 0.47835 -0.6
BXD40 m 0.12587 0.03075   5 0.01375 0.2443 0.09207, 0.15362 -0.73
BXD43 m 0.69559 0.41445   4 0.20722 0.5958 0.35974, 1.2583 -0.1
BXD45 m 0.3719 0.16566   3 0.09564 0.4454 0.19247, 0.51903 -0.46
BXD48 m 1.2625 1.413   5 0.63192 1.1192 0.44622, 3.7554 0.52
BXD48a m 2.448 0.97331   4 0.48665 0.3976 1.5344, 3.8021 1.84
BXD49 m 0.47769 0.07366   5 0.03294 0.1542 0.42236, 0.60462 -0.34
BXD51 m 2.8243 3.4255   5 1.5319 1.2129 0.84676, 8.8942 2.25
BXD53 m 0.11988 0.04212   5 0.01884 0.3513 0.05543, 0.17283 -0.74
BXD55 m 0.5464 0.26209   5 0.11721 0.4797 0.22674, 0.87159 -0.27
BXD6 m 4.6012 2.5939   5 1.16 0.5637 0.18813, 6.8007 4.22
BXD62 m 0.5434 0.27798   5 0.12432 0.5116 0.19342, 0.8751 -0.27
BXD63 m 0.14384 0.09001   5 0.04025 0.6258 0.07869, 0.30194 -0.71
BXD64 m 0.16784 0.02637   5 0.01179 0.1571 0.13679, 0.20161 -0.69
BXD66 m 0.60063 0.31361   5 0.14025 0.5221 0.23046, 0.98521 -0.21
BXD67 m 0.83359 0.27801   4 0.139 0.3335 0.44661, 1.1085 0.05
BXD69 m 0.28907 0.1655   5 0.07401 0.5725 0.14925, 0.49323 -0.55
BXD73 m 0.81808 0.68302   5 0.30545 0.8349 0.3117, 1.9965 0.03
BXD75 m 0.54016 0.41803   5 0.18695 0.7739 0.17561, 1.0796 -0.27
BXD77 m 0.48522 0.39639   5 0.17727 0.8169 0.24, 1.1698 -0.34
BXD79 m 0.39659 0.1673   5 0.07482 0.4218 0.14398, 0.60623 -0.43
BXD8 m 0.18089 0.15541   5 0.0695 0.8592 0.07935, 0.44926 -0.67
BXD81 m 1.4981 2.708   5 1.211 1.8076 0.15193, 6.3358 0.79
BXD84 m 0.13871 0.04958   5 0.02217 0.3574 0.0795, 0.21438 -0.72
BXD87 m 0.35849 0.16061   5 0.07183 0.448 0.19267, 0.61661 -0.48
BXD89 m 0.99168 0.58608   5 0.2621 0.591 0.67529, 2.0364 0.22
BXD90 m 1.4422 1.1951   5 0.53448 0.8287 0.35768, 3.1719 0.72
C57BL/6J m 0.29723 0.17981   10 0.05686 0.6049 0.10843, 0.70682 -0.54
DBA/2J m 0.82792 0.38574   5 0.17251 0.4659 0.35971, 1.2341 0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.331616 0.4333522595 2.1884304342 0.4748015658
BXD100 m 1.18872 0.4333522595 2.0455344342 0.3319055658
BXD11 m 0.446695 0.4845025552 1.4046426595 -0.5112526595
BXD12 m 0.1605025 0.4845025552 1.1184501595 -0.7974451595
BXD27 m 0.520135 0.4845025552 1.4780826595 -0.4378126595
BXD32 m 0.4255125 0.4845025552 1.3834601595 -0.5324351595
BXD34 m 0.0376875 0.4845025552 0.9956351595 -0.9202601595
BXD39 m 0.24706 0.4333522595 1.1038744342 -0.6097544342
BXD40 m 0.125872 0.4333522595 0.9826864342 -0.7309424342
BXD43 m 0.6955875 0.4845025552 1.6535351595 -0.2623601595
BXD45 m 0.3719033333 0.5594553613 1.4780460115 -0.7342393449
BXD48 m 1.262532 0.4333522595 2.1193464342 0.4057175658
BXD48a m 2.447975 0.4845025552 3.4059226595 1.4900273405
BXD49 m 0.477692 0.4333522595 1.3345064342 -0.3791224342
BXD51 m 2.824252 0.4333522595 3.6810664342 1.9674375658
BXD53 m 0.11988 0.4333522595 0.9766944342 -0.7369344342
BXD55 m 0.546398 0.4333522595 1.4032124342 -0.3104164342
BXD6 m 4.601226 0.4333522595 5.4580404342 3.7444115658
BXD62 m 0.543398 0.4333522595 1.4002124342 -0.3134164342
BXD63 m 0.14384 0.4333522595 1.0006544342 -0.7129744342
BXD64 m 0.167842 0.4333522595 1.0246564342 -0.6889724342
BXD66 m 0.600628 0.4333522595 1.4574424342 -0.2561864342
BXD67 m 0.8335875 0.4845025552 1.7915351595 -0.1243601595
BXD69 m 0.289068 0.4333522595 1.1458824342 -0.5677464342
BXD73 m 0.818082 0.4333522595 1.6748964342 -0.0387324342
BXD75 m 0.54016 0.4333522595 1.3969744342 -0.3166544342
BXD77 m 0.485222 0.4333522595 1.3420364342 -0.3715924342
BXD79 m 0.396586 0.4333522595 1.2534004342 -0.4602284342
BXD8 m 0.180886 0.4333522595 1.0377004342 -0.6759284342
BXD81 m 1.498068 0.4333522595 2.3548824342 0.6412535658
BXD84 m 0.13871 0.4333522595 0.9955244342 -0.7181044342
BXD87 m 0.358488 0.4333522595 1.2153024342 -0.4983264342
BXD89 m 0.991676 0.4333522595 1.8484904342 0.1348615658
BXD90 m 1.442202 0.4333522595 2.2990164342 0.5853875658
C57BL/6J m 0.297228 0.3064263213 0.9030872967 -0.3086312967
DBA/2J m 0.827918 0.4333522595 1.6847324342 -0.0288964342




  GWAS USING LINEAR MIXED MODELS