Project measure / variable:   Schoonjans1   wMCA_plasma_t60_HFD

ID, description, units MPD:112753   wMCA_plasma_t60_HFD   plasma bile acid ω-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ω-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means44.476   ng/mL
Median of the strain means34.527   ng/mL
SD of the strain means± 34.119
Coefficient of variation (CV)0.7671
Min–max range of strain means6.0744   –   161.2   ng/mL
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 158054.2746 4515.8364 2.2384 0.0007
Residuals 120 242096.3983 2017.47


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 19.692 7.1642   5 3.2039 0.3638 12.454, 27.622 -0.73
BXD100 m 14.705 8.7607   9 2.9202 0.5958 4.516, 31.01 -0.87
BXD11 m 161.2 218.6   3 126.2 1.3567 25.984, 413.4 3.42
BXD12 m 100.7 86.14   4 43.072 0.8555 26.66, 224.4 1.65
BXD27 m 15.604 12.573   5 5.6229 0.8058 4.142, 36.5 -0.85
BXD32 m 12.377 3.042   4 1.521 0.2458 9.946, 16.544 -0.94
BXD34 m 36.534 8.1532   4 4.0766 0.2232 26.562, 45.532 -0.23
BXD39 m 28.961 12.928   3 7.4638 0.4464 14.046, 36.954 -0.45
BXD40 m 133.9 52.51   4 26.256 0.3921 102.4, 212.0 2.62
BXD43 m 28.823 7.2748   5 3.2534 0.2524 18.608, 38.436 -0.46
BXD45 m 65.24 19.751   5 8.8329 0.3028 45.368, 91.3 0.61
BXD48 m 39.319 15.126   5 6.7646 0.3847 21.794, 52.39 -0.15
BXD48a m 30.206 7.0924   4 3.5462 0.2348 22.35, 39.526 -0.42
BXD49 m 76.04 75.51   5 33.77 0.993 32.144, 210.7 0.93
BXD51 m 17.036 11.645   3 6.723 0.6835 8.7519, 30.35 -0.8
BXD53 m 41.361 11.081   5 4.9556 0.2679 29.782, 52.19 -0.09
BXD55 m 25.817 19.438   5 8.6931 0.7529 8.89, 58.36 -0.55
BXD6 m 78.81 59.46   5 26.593 0.7545 12.758, 136.7 1.01
BXD62 m 40.174 27.007   4 13.503 0.6722 15.788, 67.86 -0.13
BXD63 m 22.539 6.583   5 2.944 0.2921 15.056, 30.64 -0.64
BXD64 m 49.254 39.89   5 17.839 0.8099 24.372, 119.9 0.14
BXD66 m 45.37 22.382   3 12.922 0.4933 28.58, 70.78 0.03
BXD67 m 30.039 10.903   5 4.8761 0.363 16.748, 45.516 -0.42
BXD69 m 18.35 8.0518   4 4.0259 0.4388 7.874, 27.356 -0.77
BXD73 m 49.127 10.723   3 6.1911 0.2183 41.35, 61.36 0.14
BXD75 m 15.05 11.819   4 5.9094 0.7853 4.918, 31.958 -0.86
BXD77 m 94.87 92.18   5 41.224 0.9716 25.524, 256.7 1.48
BXD79 m 38.131 27.172   5 12.152 0.7126 10.902, 75.98 -0.19
BXD8 m 19.3 9.1019   2   6.436 0.4716 12.864, 25.736 -0.74
BXD81 m 42.301 12.861   5 5.7517 0.304 24.138, 58.34 -0.06
BXD84 m 62.76 74.0   5 33.092 1.179 8.808, 185.8 0.54
BXD87 m 31.635 13.092   4 6.5462 0.4139 20.81, 48.194 -0.38
BXD89 m 52.75 8.981   5 4.0164 0.1702 45.17, 67.29 0.24
BXD90 m 24.584 9.0631   4 4.5315 0.3687 16.987, 36.356 -0.58
C57BL/6J m 32.52 12.205   2   8.63 0.3753 23.89, 41.15 -0.35
DBA/2J m 6.0744 2.3126   3 1.3352 0.3807 3.598, 8.178 -1.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 19.6916 20.0871600094 59.4627788544 -20.0795788544
BXD100 m 14.7048888889 14.9720850853 44.3485753768 -14.9387975991
BXD11 m 161.152 25.932412063 212.4963711208 109.8076288792
BXD12 m 100.69 22.458127628 145.1555297319 56.2244702681
BXD27 m 15.6036 20.0871600094 55.3747788544 -24.1675788544
BXD32 m 12.377 22.458127628 56.8425297319 -32.0885297319
BXD34 m 36.534 22.458127628 80.9995297319 -7.9315297319
BXD39 m 28.9606666667 25.932412063 80.3050377874 -22.3837044541
BXD40 m 133.925 22.458127628 178.3905297319 89.4594702681
BXD43 m 28.8234 20.0871600094 68.5945788544 -10.9477788544
BXD45 m 65.236 20.0871600094 105.0071788544 25.4648211456
BXD48 m 39.3188 20.0871600094 79.0899788544 -0.4523788544
BXD48a m 30.2055 22.458127628 74.6710297319 -14.2600297319
BXD49 m 76.044 20.0871600094 115.8151788544 36.2728211456
BXD51 m 17.0359666667 25.932412063 68.3803377874 -34.3084044541
BXD53 m 41.3608 20.0871600094 81.1319788544 1.5896211456
BXD55 m 25.8172 20.0871600094 65.5883788544 -13.9539788544
BXD6 m 78.8116 20.0871600094 118.5827788544 39.0404211456
BXD62 m 40.174 22.458127628 84.6395297319 -4.2915297319
BXD63 m 22.5386 20.0871600094 62.3097788544 -17.2325788544
BXD64 m 49.2544 20.0871600094 89.0255788544 9.4832211456
BXD66 m 45.37 25.932412063 96.7143711208 -5.9743711208
BXD67 m 30.0392 20.0871600094 69.8103788544 -9.7319788544
BXD69 m 18.35 22.458127628 62.8155297319 -26.1155297319
BXD73 m 49.1273333333 25.932412063 100.4717044541 -2.2170377874
BXD75 m 15.05 22.458127628 59.5155297319 -29.4155297319
BXD77 m 94.8708 20.0871600094 134.6419788544 55.0996211456
BXD79 m 38.1312 20.0871600094 77.9023788544 -1.6399788544
BXD8 m 19.3 31.760588677 82.183755205 -43.583755205
BXD81 m 42.3008 20.0871600094 82.0719788544 2.5296211456
BXD84 m 62.7592 20.0871600094 102.5303788544 22.9880211456
BXD87 m 31.635 22.458127628 76.1005297319 -12.8305297319
BXD89 m 52.7524 20.0871600094 92.5235788544 12.9812211456
BXD90 m 24.58375 22.458127628 69.0492797319 -19.8817797319
C57BL/6J m 32.52 31.760588677 95.403755205 -30.363755205
DBA/2J m 6.0743666667 25.932412063 57.4187377874 -45.2700044541




  GWAS USING LINEAR MIXED MODELS