Project measure / variable:   Schoonjans1   UDCA_plasma_t60_HFD

ID, description, units MPD:112751   UDCA_plasma_t60_HFD   plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   28 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested28 strains
Mean of the strain means5.0543   ng/mL
Median of the strain means3.6422   ng/mL
SD of the strain means± 4.5541
Coefficient of variation (CV)0.901
Min–max range of strain means1.6621   –   22.616   ng/mL
Mean sample size per strain2.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 2063.3881 93.7904 0.6693 0.8451
Residuals 46 6446.3718 140.1385


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 2.606 0.63357   2   0.448 0.2431 2.158, 3.054 -0.54
BXD100 m 1.985 0.76792   2   0.543 0.3869 1.442, 2.528 -0.67
BXD11 m 4.717 4.377   2   3.095 0.9279 1.622, 7.812 -0.07
BXD12 m 6.9185 5.8021   4 2.901 0.8386 2.254, 15.342 0.41
BXD27 m 9.225 9.2108   2   6.513 0.9985 2.712, 15.738 0.92
BXD32 m 1.862 0.17536   2   0.124 0.0942 1.738, 1.986 -0.7
BXD34 m 2.452 0.0   1   0.0 0.0 2.452, 2.452 -0.57
BXD39 m 4.784 0.0   1   0.0 0.0 4.784, 4.784 -0.06
BXD40 m 10.47 0.39891   4 0.19946 0.0381 10.116, 10.88 1.19
BXD45 m 3.6016 0.8181   5 0.36587 0.2271 2.352, 4.408 -0.32
BXD48 m 2.963 1.7409   2   1.231 0.5875 1.732, 4.194 -0.46
BXD48a m 3.067 1.134   4 0.567 0.3697 1.45, 3.942 -0.44
BXD49 m 22.616 38.897   5 17.395 1.7199 1.644, 91.73 3.86
BXD53 m 2.612 0.0   1   0.0 0.0 2.612, 2.612 -0.54
BXD55 m 3.6828 1.8606   5 0.83209 0.5052 2.194, 6.662 -0.3
BXD6 m 4.8515 2.499   3 1.4428 0.5151 2.682, 7.584 -0.04
BXD62 m 15.15 8.72   2   6.166 0.5756 8.984, 21.316 2.22
BXD63 m 1.6621 0.37349   2   0.2641 0.2247 1.398, 1.9262 -0.74
BXD64 m 4.818 0.0   1   0.0 0.0 4.818, 4.818 -0.05
BXD69 m 6.855 6.6058   2   4.671 0.9636 2.184, 11.526 0.4
BXD73 m 2.62 1.4264   3 0.82354 0.5444 1.214, 4.066 -0.53
BXD77 m 3.699 1.4156   2   1.001 0.3827 2.698, 4.7 -0.3
BXD79 m 3.7408 2.0163   5 0.9017 0.539 1.614, 6.908 -0.29
BXD81 m 3.0393 0.70858   3 0.4091 0.2331 2.398, 3.8 -0.44
BXD84 m 2.542 0.0   1   0.0 0.0 2.542, 2.542 -0.55
BXD87 m 3.7913 1.902   3 1.0981 0.5017 2.438, 5.966 -0.28
BXD89 m 2.9127 0.86789   3 0.50108 0.298 1.958, 3.654 -0.47
BXD90 m 2.277 0.38042   2   0.269 0.1671 2.008, 2.546 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 2.606 8.3707382527 19.4554221885 -14.2434221885
BXD100 m 1.985 8.3707382527 18.8344221885 -14.8644221885
BXD11 m 4.717 8.3707382527 21.5664221885 -12.1324221885
BXD12 m 6.9185 5.919005782 18.8328406886 -4.9958406886
BXD27 m 9.225 8.3707382527 26.0744221885 -7.6244221885
BXD32 m 1.862 8.3707382527 18.7114221885 -14.9874221885
BXD40 m 10.47 5.919005782 22.3843406886 -1.4443406886
BXD45 m 3.6016 5.2941197151 14.2581102747 -7.0549102747
BXD48 m 2.963 8.3707382527 19.8124221885 -13.8864221885
BXD48a m 3.067 5.919005782 14.9813406886 -8.8473406886
BXD49 m 22.616 5.2941197151 33.2725102747 11.9594897253
BXD55 m 3.6828 5.2941197151 14.3393102747 -6.9737102747
BXD6 m 4.8515333333 6.8346791632 18.6090289409 -8.9059622742
BXD62 m 15.15 8.3707382527 31.9994221885 -1.6994221885
BXD63 m 1.6621 8.3707382527 18.5115221885 -15.1873221885
BXD69 m 6.855 8.3707382527 23.7044221885 -9.9944221885
BXD73 m 2.62 6.8346791632 16.3774956075 -11.1374956075
BXD77 m 3.699 8.3707382527 20.5484221885 -13.1504221885
BXD79 m 3.7408 5.2941197151 14.3973102747 -6.9157102747
BXD81 m 3.0393333333 6.8346791632 16.7968289409 -10.7181622742
BXD87 m 3.7913333333 6.8346791632 17.5488289409 -9.9661622742
BXD89 m 2.9126666667 6.8346791632 16.6701622742 -10.8448289409
BXD90 m 2.277 8.3707382527 19.1264221885 -14.5724221885




  GWAS USING LINEAR MIXED MODELS