Project measure / variable:   Schoonjans1   UDCA_plasma_t60_CD

ID, description, units MPD:112750   UDCA_plasma_t60_CD   plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   28 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested28 strains
Mean of the strain means5.088   ng/mL
Median of the strain means3.6585   ng/mL
SD of the strain means± 4.9258
Coefficient of variation (CV)0.9681
Min–max range of strain means1.6333   –   27.978   ng/mL
Mean sample size per strain2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 19 2673.9598 140.7347 1.0731 0.4173
Residuals 33 4328.0031 131.1516


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 2.038 0.0   1   0.0 0.0 2.038, 2.038 -0.62
BXD11 m 1.652 0.0   1   0.0 0.0 1.652, 1.652 -0.7
BXD12 m 3.434 2.9359   2   2.076 0.855 1.358, 5.51 -0.34
BXD27 m 4.859 0.99419   2   0.703 0.2046 4.156, 5.562 -0.05
BXD32 m 6.8607 6.8951   3 3.9809 1.005 2.274, 14.79 0.36
BXD34 m 2.143 0.62933   2   0.445 0.2937 1.698, 2.588 -0.6
BXD40 m 3.684 3.6038   3 2.0807 0.9782 1.302, 7.83 -0.29
BXD43 m 5.02 0.0   1   0.0 0.0 5.02, 5.02 -0.01
BXD45 m 7.797 6.9169   2   4.891 0.8871 2.906, 12.688 0.55
BXD48 m 2.143 1.13   2   0.799 0.5273 1.344, 2.942 -0.6
BXD48a m 1.6333 0.21757   3 0.12561 0.1332 1.442, 1.87 -0.7
BXD49 m 4.006 2.7291   3 1.5757 0.6813 1.488, 6.906 -0.22
BXD55 m 3.433 1.2172   4 0.60862 0.3546 1.828, 4.712 -0.34
BXD6 m 27.978 30.511   5 13.645 1.0905 5.566, 80.0 4.65
BXD62 m 4.96 1.5613   2   1.104 0.3148 3.856, 6.064 -0.03
BXD63 m 3.584 0.0   1   0.0 0.0 3.584, 3.584 -0.31
BXD69 m 5.094 0.0   1   0.0 0.0 5.094, 5.094 0.0
BXD73 m 5.5647 6.3059   3 3.6407 1.1332 1.9, 12.846 0.1
BXD75 m 2.976 0.0   1   0.0 0.0 2.976, 2.976 -0.43
BXD77 m 9.716 10.215   3 5.8976 1.0514 3.244, 21.492 0.94
BXD79 m 3.387 1.97   2   1.393 0.5816 1.994, 4.78 -0.35
BXD8 m 2.012 0.0   1   0.0 0.0 2.012, 2.012 -0.62
BXD81 m 3.31 0.0   1   0.0 0.0 3.31, 3.31 -0.36
BXD87 m 7.059 2.2415   2   1.585 0.3175 5.474, 8.644 0.4
BXD89 m 7.256 6.8731   2   4.86 0.9472 2.396, 12.116 0.44
BXD90 m 3.633 0.45113   2   0.319 0.1242 3.314, 3.952 -0.3
C57BL/6J m 4.7735 4.3482   4 2.1741 0.9109 1.738, 11.212 -0.06
DBA/2J m 2.459 0.97722   2   0.691 0.3974 1.768, 3.15 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD12 m 3.434 8.0978888553 19.9092787531 -13.0412787531
BXD27 m 4.859 8.0978888553 21.3342787531 -11.6162787531
BXD32 m 6.8606666667 6.6118985631 20.3126754384 -6.591342105
BXD34 m 2.143 8.0978888553 18.6182787531 -14.3322787531
BXD40 m 3.684 6.6118985631 17.1360087717 -9.7680087717
BXD45 m 7.797 8.0978888553 24.2722787531 -8.6782787531
BXD48 m 2.143 8.0978888553 18.6182787531 -14.3322787531
BXD48a m 1.6333333333 6.6118985631 15.085342105 -11.8186754384
BXD49 m 4.006 6.6118985631 17.4580087717 -9.4460087717
BXD55 m 3.433 5.7260721228 15.0827813282 -8.2167813282
BXD6 m 27.9784 5.1215546043 38.3982811892 17.5585188108
BXD62 m 4.96 8.0978888553 21.4352787531 -11.5152787531
BXD73 m 5.5646666667 6.6118985631 19.0166754384 -7.887342105
BXD77 m 9.716 6.6118985631 23.1680087717 -3.7360087717
BXD79 m 3.387 8.0978888553 19.8622787531 -13.0882787531
BXD87 m 7.059 8.0978888553 23.5342787531 -9.4162787531
BXD89 m 7.256 8.0978888553 23.7312787531 -9.2192787531
BXD90 m 3.633 8.0978888553 20.1082787531 -12.8422787531
C57BL/6J m 4.7735 5.7260721228 16.4232813282 -6.8762813282
DBA/2J m 2.459 8.0978888553 18.9342787531 -14.0162787531




  GWAS USING LINEAR MIXED MODELS