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Project measure / variable:   Schoonjans1   TUDCA_plasma_t60_CD

ID, description, units MPD:112748   TUDCA_plasma_t60_CD   plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means14.44   ng/mL
Median of the strain means11.5   ng/mL
SD of the strain means± 9.6225
Coefficient of variation (CV)0.6664
Min–max range of strain means3.6132   –   35.875   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 14240.7456 406.8784 5.1064 < 0.0001
Residuals 127 10119.377 79.6801


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.6132 1.6638   5 0.74408 0.4605 1.56, 5.772 -1.13
BXD100 m 20.434 5.1167   5 2.2883 0.2504 13.378, 27.174 0.62
BXD11 m 9.656 4.6294   4 2.3147 0.4794 3.524, 14.592 -0.5
BXD12 m 32.092 11.268   3 6.5055 0.3511 23.22, 44.77 1.83
BXD27 m 4.0542 5.4565   3 3.1503 1.3459 0.026, 10.264 -1.08
BXD32 m 7.058 4.8408   5 2.1649 0.6859 2.61, 14.446 -0.77
BXD34 m 5.0064 2.4043   5 1.0753 0.4803 2.7, 8.802 -0.98
BXD39 m 4.6427 2.3967   3 1.3838 0.5162 2.524, 7.244 -1.02
BXD40 m 26.462 3.2459   4 1.623 0.1227 22.682, 30.594 1.25
BXD43 m 5.2517 4.7847   7 1.8085 0.9111 1.12, 12.874 -0.95
BXD45 m 23.526 3.7245   4 1.8622 0.1583 20.104, 27.098 0.94
BXD48 m 16.456 8.6879   5 3.8854 0.5279 11.122, 31.854 0.21
BXD48a m 35.875 29.975   4 14.987 0.8355 9.764, 71.3 2.23
BXD49 m 23.827 5.761   5 2.5764 0.2418 15.96, 30.334 0.98
BXD51 m 15.039 6.2089   5 2.7767 0.4129 7.664, 24.864 0.06
BXD53 m 21.21 10.759   4 5.3794 0.5073 6.058, 29.548 0.7
BXD55 m 6.678 1.9163   5 0.85701 0.287 5.308, 10.012 -0.81
BXD6 m 33.614 29.837   5 13.343 0.8876 6.066, 67.03 1.99
BXD62 m 18.14 4.7893   5 2.1419 0.264 13.522, 23.496 0.38
BXD63 m 5.2095 2.5256   4 1.2628 0.4848 2.408, 7.5 -0.96
BXD64 m 15.354 3.8336   5 1.7144 0.2497 12.49, 20.748 0.09
BXD66 m 10.169 4.9828   5 2.2284 0.49 4.74, 16.902 -0.44
BXD67 m 4.5765 3.2114   4 1.6057 0.7017 1.888, 9.22 -1.03
BXD69 m 8.8436 2.0459   5 0.91496 0.2313 6.272, 11.654 -0.58
BXD73 m 9.2775 7.4097   4 3.7049 0.7987 2.252, 19.738 -0.54
BXD75 m 11.117 14.01   3 8.0888 1.2603 2.95, 27.294 -0.35
BXD77 m 6.0536 2.993   5 1.3385 0.4944 2.124, 9.236 -0.87
BXD79 m 16.373 5.0975   5 2.2797 0.3113 10.528, 24.098 0.2
BXD8 m 14.555 3.9735   5 1.777 0.273 12.044, 21.494 0.01
BXD81 m 11.883 4.2448   3 2.4507 0.3572 6.998, 14.676 -0.27
BXD84 m 27.882 7.4855   5 3.3476 0.2685 16.256, 35.162 1.4
BXD87 m 5.5784 1.4796   5 0.66169 0.2652 3.954, 7.356 -0.92
BXD89 m 7.6712 5.5997   5 2.5043 0.73 2.038, 16.672 -0.7
BXD90 m 16.704 6.9367   5 3.1022 0.4153 11.116, 27.89 0.24
C57BL/6J m 31.557 9.5512   5 4.2714 0.3027 21.154, 44.176 1.78
DBA/2J m 4.4145 4.1261   4 2.063 0.9347 1.284, 10.484 -1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.6132 3.9919953403 11.5126383618 -4.2862383618
BXD100 m 20.4344 3.9919953403 28.3338383618 12.5349616382
BXD11 m 9.656 4.4631864734 18.4878405805 0.8241594195
BXD12 m 32.092 5.1536438237 42.2901310732 21.8938689268
BXD27 m 4.0542333333 5.1536438237 14.2523644065 -6.1438977399
BXD32 m 7.058 3.9919953403 14.9574383618 -0.8414383618
BXD34 m 5.0064 3.9919953403 12.9058383618 -2.8930383618
BXD39 m 4.6426666667 5.1536438237 14.8407977399 -5.5554644065
BXD40 m 26.4615 4.4631864734 35.2933405805 17.6296594195
BXD43 m 5.2517142857 3.3738518467 11.9279582271 -1.4245296557
BXD45 m 23.526 4.4631864734 32.3578405805 14.6941594195
BXD48 m 16.456 3.9919953403 24.3554383618 8.5565616382
BXD48a m 35.875 4.4631864734 44.7068405805 27.0431594195
BXD49 m 23.8272 3.9919953403 31.7266383618 15.9277616382
BXD51 m 15.0392 3.9919953403 22.9386383618 7.1397616382
BXD53 m 21.21 4.4631864734 30.0418405805 12.3781594195
BXD55 m 6.678 3.9919953403 14.5774383618 -1.2214383618
BXD6 m 33.614 3.9919953403 41.5134383618 25.7145616382
BXD62 m 18.1396 3.9919953403 26.0390383618 10.2401616382
BXD63 m 5.2095 4.4631864734 14.0413405805 -3.6223405805
BXD64 m 15.3544 3.9919953403 23.2538383618 7.4549616382
BXD66 m 10.1692 3.9919953403 18.0686383618 2.2697616382
BXD67 m 4.5765 4.4631864734 13.4083405805 -4.2553405805
BXD69 m 8.8436 3.9919953403 16.7430383618 0.9441616382
BXD73 m 9.2775 4.4631864734 18.1093405805 0.4456594195
BXD75 m 11.1166666667 5.1536438237 21.3147977399 0.9185355935
BXD77 m 6.0536 3.9919953403 13.9530383618 -1.8458383618
BXD79 m 16.3732 3.9919953403 24.2726383618 8.4737616382
BXD8 m 14.5548 3.9919953403 22.4542383618 6.6553616382
BXD81 m 11.8826666667 5.1536438237 22.0807977399 1.6845355935
BXD84 m 27.8816 3.9919953403 35.7810383618 19.9821616382
BXD87 m 5.5784 3.9919953403 13.4778383618 -2.3210383618
BXD89 m 7.6712 3.9919953403 15.5706383618 -0.2282383618
BXD90 m 16.704 3.9919953403 24.6034383618 8.8045616382
C57BL/6J m 31.5572 3.9919953403 39.4566383618 23.6577616382
DBA/2J m 4.4145 4.4631864734 13.2463405805 -4.4173405805




  GWAS USING LINEAR MIXED MODELS