Project measure / variable:   Schoonjans1   THDCA_plasma_t60_HFD

ID, description, units MPD:112747   THDCA_plasma_t60_HFD   plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means17.921   ng/mL
Median of the strain means12.93   ng/mL
SD of the strain means± 16.472
Coefficient of variation (CV)0.9192
Min–max range of strain means2.438   –   72.56   ng/mL
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 33948.2758 969.9507 3.9423 < 0.0001
Residuals 118 29032.0609 246.0344


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 7.592 2.7367   5 1.2239 0.3605 5.23, 11.702 -0.63
BXD100 m 5.976 4.1383   8 1.4631 0.6925 0.694, 14.374 -0.73
BXD11 m 4.652 3.923   2   2.774 0.8433 1.878, 7.426 -0.81
BXD12 m 44.649 44.045   4 22.023 0.9865 3.972, 97.78 1.62
BXD27 m 6.0988 3.1671   5 1.4163 0.5193 2.804, 10.22 -0.72
BXD32 m 3.163 1.6829   4 0.84143 0.532 1.074, 4.72 -0.9
BXD34 m 16.198 17.705   4 8.8527 1.0931 4.106, 42.24 -0.1
BXD39 m 14.376 15.171   3 8.7587 1.0553 4.62, 31.854 -0.22
BXD40 m 28.739 6.6722   4 3.3361 0.2322 24.064, 38.37 0.66
BXD43 m 3.9514 1.7485   5 0.78195 0.4425 2.166, 6.425 -0.85
BXD45 m 14.676 5.3704   5 2.4017 0.3659 6.7, 19.69 -0.2
BXD48 m 36.482 18.773   5 8.3953 0.5146 11.268, 54.96 1.13
BXD48a m 24.241 16.245   4 8.1225 0.6701 4.898, 44.474 0.38
BXD49 m 12.375 5.1085   5 2.2846 0.4128 8.524, 20.128 -0.34
BXD51 m 11.178 9.4237   3 5.4408 0.8431 2.696, 21.322 -0.41
BXD53 m 13.518 10.256   5 4.5868 0.7587 3.578, 27.418 -0.27
BXD55 m 3.6084 0.90817   5 0.40614 0.2517 2.178, 4.59 -0.87
BXD6 m 7.3901 7.0234   5 3.141 0.9504 0.744, 18.914 -0.64
BXD62 m 2.438 0.88963   4 0.44482 0.3649 1.3, 3.39 -0.94
BXD63 m 10.59 5.2618   5 2.3531 0.4969 5.268, 16.248 -0.45
BXD64 m 12.942 10.069   5 4.5029 0.778 2.974, 29.204 -0.3
BXD66 m 12.918 2.5691   3 1.4833 0.1989 11.244, 15.876 -0.3
BXD67 m 3.115 2.2061   5 0.98658 0.7082 1.8, 7.044 -0.9
BXD69 m 63.69 47.178   4 23.589 0.7408 10.566, 123.7 2.78
BXD73 m 25.402 15.933   3 9.199 0.6272 9.79, 41.638 0.45
BXD75 m 22.586 15.688   4 7.8442 0.6946 9.986, 44.278 0.28
BXD77 m 18.873 14.189   5 6.3454 0.7518 6.238, 38.452 0.06
BXD79 m 15.662 12.199   5 5.4556 0.7789 1.154, 28.8 -0.14
BXD8 m 7.329 3.4889   2   2.467 0.476 4.862, 9.796 -0.64
BXD81 m 43.276 19.451   5 8.6987 0.4495 10.282, 59.8 1.54
BXD84 m 30.658 19.746   5 8.8309 0.6441 7.182, 61.18 0.77
BXD87 m 11.103 8.7776   4 4.3888 0.7906 1.74, 22.944 -0.41
BXD89 m 15.676 5.5846   5 2.4975 0.3562 10.712, 25.038 -0.14
BXD90 m 7.9139 1.4778   4 0.73891 0.1867 5.8179, 9.046 -0.61
C57BL/6J m 72.56 68.78   2   48.638 0.9479 23.924, 121.2 3.32
DBA/2J m 9.5538 9.4226   3 5.4401 0.9863 1.686, 19.996 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 7.592 7.0147617853 21.4831380986 -6.2991380986
BXD100 m 5.976 5.5456561212 16.9579089209 -5.0059089209
BXD11 m 4.652 11.0913122425 26.6158178418 -17.3118178418
BXD12 m 44.649 7.8427420989 60.1797645367 29.1182354633
BXD27 m 6.0988 7.0147617853 19.9899380986 -7.7923380986
BXD32 m 3.163 7.8427420989 18.6937645367 -12.3677645367
BXD34 m 16.198 7.8427420989 31.7287645367 0.6672354633
BXD39 m 14.376 9.056018524 32.309382172 -3.557382172
BXD40 m 28.7385 7.8427420989 44.2692645367 13.2077354633
BXD43 m 3.9514 7.0147617853 17.8425380986 -9.9397380986
BXD45 m 14.676 7.0147617853 28.5671380986 0.7848619014
BXD48 m 36.4816 7.0147617853 50.3727380986 22.5904619014
BXD48a m 24.241 7.8427420989 39.7717645367 8.7102354633
BXD49 m 12.3752 7.0147617853 26.2663380986 -1.5159380986
BXD51 m 11.1776 9.056018524 29.110982172 -6.755782172
BXD53 m 13.5184 7.0147617853 27.4095380986 -0.3727380986
BXD55 m 3.6084 7.0147617853 17.4995380986 -10.2827380986
BXD6 m 7.39014 7.0147617853 21.2812780986 -6.5009980986
BXD62 m 2.438 7.8427420989 17.9687645367 -13.0927645367
BXD63 m 10.5895 7.0147617853 24.4806380986 -3.3016380986
BXD64 m 12.9424 7.0147617853 26.8335380986 -0.9487380986
BXD66 m 12.918 9.056018524 30.851382172 -5.015382172
BXD67 m 3.11498 7.0147617853 17.0061180986 -10.7761580986
BXD69 m 63.6885 7.8427420989 79.2192645367 48.1577354633
BXD73 m 25.402 9.056018524 43.335382172 7.468617828
BXD75 m 22.586 7.8427420989 38.1167645367 7.0552354633
BXD77 m 18.8732 7.0147617853 32.7643380986 4.9820619014
BXD79 m 15.6624 7.0147617853 29.5535380986 1.7712619014
BXD8 m 7.329 11.0913122425 29.2928178418 -14.6348178418
BXD81 m 43.2756 7.0147617853 57.1667380986 29.3844619014
BXD84 m 30.6584 7.0147617853 44.5495380986 16.7672619014
BXD87 m 11.103 7.8427420989 26.6337645367 -4.4277645367
BXD89 m 15.6764 7.0147617853 29.5675380986 1.7852619014
BXD90 m 7.91395 7.8427420989 23.4447145367 -7.6168145367
C57BL/6J m 72.562 11.0913122425 94.5258178418 50.5981821582
DBA/2J m 9.5538 9.056018524 27.487182172 -8.379582172




  GWAS USING LINEAR MIXED MODELS