Project measure / variable:   Schoonjans1   THDCA_plasma_t60_CD

ID, description, units MPD:112746   THDCA_plasma_t60_CD   plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means23.704   ng/mL
Median of the strain means17.427   ng/mL
SD of the strain means± 19.017
Coefficient of variation (CV)0.8023
Min–max range of strain means0.764   –   75.85   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 54384.7952 1553.8513 3.6285 < 0.0001
Residuals 127 54385.4083 428.2316


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 8.876 4.4018   5 1.9685 0.4959 2.622, 14.87 -0.78
BXD100 m 14.786 7.7627   5 3.4716 0.525 8.676, 27.556 -0.47
BXD11 m 7.6925 4.7705   4 2.3852 0.6201 1.392, 12.952 -0.84
BXD12 m 49.139 28.574   3 16.497 0.5815 23.62, 80.01 1.34
BXD27 m 13.483 17.946   4 8.9732 1.331 3.882, 40.384 -0.54
BXD32 m 26.922 21.221   5 9.4904 0.7883 3.462, 53.1 0.17
BXD34 m 10.774 3.5077   5 1.5687 0.3256 5.962, 15.568 -0.68
BXD39 m 13.733 5.5398   3 3.1984 0.4034 8.978, 19.816 -0.52
BXD40 m 53.12 17.736   4 8.8681 0.3339 30.732, 71.18 1.55
BXD43 m 3.9671 4.2148   7 1.5931 1.0624 1.176, 13.092 -1.04
BXD45 m 57.18 28.233   4 14.117 0.4938 33.832, 97.25 1.76
BXD48 m 64.1 43.738   5 19.56 0.6823 17.772, 134.1 2.12
BXD48a m 22.354 20.841   4 10.421 0.9323 3.03, 49.08 -0.07
BXD49 m 28.581 11.94   5 5.3395 0.4177 10.79, 40.676 0.26
BXD51 m 7.074 2.3224   5 1.0386 0.3283 3.984, 9.42 -0.87
BXD53 m 45.37 31.581   4 15.79 0.6961 10.686, 86.51 1.14
BXD55 m 7.8436 5.0582   5 2.2621 0.6449 3.118, 14.218 -0.83
BXD6 m 0.764 0.15274   2   0.108 0.1999 0.656, 0.872 -1.21
BXD62 m 7.1004 7.0746   5 3.1639 0.9964 1.406, 16.626 -0.87
BXD63 m 14.853 11.174   4 5.5869 0.7523 4.972, 26.624 -0.47
BXD64 m 10.966 3.0815   5 1.3781 0.281 6.966, 14.966 -0.67
BXD66 m 3.972 1.8458   5 0.82548 0.4647 1.74, 6.852 -1.04
BXD67 m 1.643 1.2728   4 0.63639 0.7747 0.73, 3.486 -1.16
BXD69 m 40.656 15.039   5 6.7257 0.3699 15.042, 51.11 0.89
BXD73 m 75.85 89.38   4 44.689 1.1783 13.586, 207.4 2.74
BXD75 m 31.315 24.21   5 10.827 0.7731 10.184, 63.58 0.4
BXD77 m 14.581 8.9567   5 4.0056 0.6143 4.762, 22.616 -0.48
BXD79 m 24.459 8.3506   5 3.7345 0.3414 10.656, 30.008 0.04
BXD8 m 34.307 12.128   5 5.4238 0.3535 21.822, 52.53 0.56
BXD81 m 28.932 26.27   3 15.167 0.908 7.45, 58.22 0.27
BXD84 m 38.958 10.772   5 4.8175 0.2765 20.406, 46.034 0.8
BXD87 m 26.354 10.133   5 4.5318 0.3845 12.6, 39.648 0.14
BXD89 m 20.0 17.705   5 7.9179 0.8852 4.836, 49.378 -0.19
BXD90 m 12.027 12.355   5 5.5254 1.0273 2.54, 33.034 -0.61
C57BL/6J m 28.476 7.6223   5 3.4088 0.2677 17.59, 36.89 0.25
DBA/2J m 3.1315 2.4842   4 1.2421 0.7933 0.024, 5.836 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 8.876 9.2545292853 27.1890433342 -9.4370433342
BXD100 m 14.7856 9.2545292853 33.0986433342 -3.5274433342
BXD11 m 7.6925 10.3468782908 28.1671048851 -12.7821048851
BXD12 m 49.1386666667 11.947545933 72.7807039506 25.4966293827
BXD27 m 13.483475 10.3468782908 33.9580798851 -6.9911298851
BXD32 m 26.9216 9.2545292853 45.2346433342 8.6085566658
BXD34 m 10.774 9.2545292853 29.0870433342 -7.5390433342
BXD39 m 13.7326666667 11.947545933 37.3747039506 -9.9093706173
BXD40 m 53.122 10.3468782908 73.5966048851 32.6473951149
BXD43 m 3.9671428571 7.821504801 19.4444893481 -11.5102036338
BXD45 m 57.1805 10.3468782908 77.6551048851 36.7058951149
BXD48 m 64.1008 9.2545292853 82.4138433342 45.7877566658
BXD48a m 22.354 10.3468782908 42.8286048851 1.8793951149
BXD49 m 28.5812 9.2545292853 46.8942433342 10.2681566658
BXD51 m 7.074 9.2545292853 25.3870433342 -11.2390433342
BXD53 m 45.37 10.3468782908 65.8446048851 24.8953951149
BXD55 m 7.8436 9.2545292853 26.1566433342 -10.4694433342
BXD6 m 0.764 14.6326956071 29.7194639128 -28.1914639128
BXD62 m 7.1004 9.2545292853 25.4134433342 -11.2126433342
BXD63 m 14.853 10.3468782908 35.3276048851 -5.6216048851
BXD64 m 10.966 9.2545292853 29.2790433342 -7.3470433342
BXD66 m 3.972 9.2545292853 22.2850433342 -14.3410433342
BXD67 m 1.643 10.3468782908 22.1176048851 -18.8316048851
BXD69 m 40.6564 9.2545292853 58.9694433342 22.3433566658
BXD73 m 75.853 10.3468782908 96.3276048851 55.3783951149
BXD75 m 31.3148 9.2545292853 49.6278433342 13.0017566658
BXD77 m 14.5808 9.2545292853 32.8938433342 -3.7322433342
BXD79 m 24.4588 9.2545292853 42.7718433342 6.1457566658
BXD8 m 34.3068 9.2545292853 52.6198433342 15.9937566658
BXD81 m 28.932 11.947545933 52.5740372839 5.2899627161
BXD84 m 38.958 9.2545292853 57.2710433342 20.6449566658
BXD87 m 26.354 9.2545292853 44.6670433342 8.0409566658
BXD89 m 20.0004 9.2545292853 38.3134433342 1.6873566658
BXD90 m 12.0272 9.2545292853 30.3402433342 -6.2858433342
C57BL/6J m 28.4756 9.2545292853 46.7886433342 10.1625566658
DBA/2J m 3.1315 10.3468782908 23.6061048851 -17.3431048851




  GWAS USING LINEAR MIXED MODELS