Project measure / variable:   Schoonjans1   TDCA_plasma_t60_HFD

ID, description, units MPD:112745   TDCA_plasma_t60_HFD   plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means59.81   ng/mL
Median of the strain means41.403   ng/mL
SD of the strain means± 51.78
Coefficient of variation (CV)0.8658
Min–max range of strain means13.908   –   268.7   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 304810.0321 8965.0009 3.6546 < 0.0001
Residuals 114 279647.2879 2453.0464


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 63.37 31.334   5 14.013 0.4945 38.4, 117.0 0.07
BXD100 m 23.391 25.77   9 8.59 1.1017 1.426, 80.19 -0.7
BXD11 m 26.266 0.0   1   0.0 0.0 26.266, 26.266 -0.65
BXD12 m 53.17 29.814   4 14.907 0.5608 13.786, 78.55 -0.13
BXD27 m 37.593 24.35   5 10.89 0.6477 10.804, 68.14 -0.43
BXD32 m 28.685 5.4629   4 2.7314 0.1904 23.196, 34.5 -0.6
BXD34 m 19.1 13.092   4 6.5461 0.6855 8.142, 36.812 -0.79
BXD39 m 46.285 54.38   3 31.397 1.1749 12.208, 109.0 -0.26
BXD40 m 41.752 15.026   4 7.5128 0.3599 27.026, 61.81 -0.35
BXD43 m 25.556 10.27   5 4.5927 0.4018 10.974, 35.718 -0.66
BXD45 m 26.824 12.318   5 5.5089 0.4592 11.828, 42.236 -0.64
BXD48 m 147.5 114.9   5 51.4 0.7792 49.04, 303.9 1.69
BXD48a m 90.36 49.804   4 24.902 0.5512 37.746, 141.7 0.59
BXD49 m 89.29 28.565   5 12.775 0.3199 54.12, 119.7 0.57
BXD51 m 40.708 28.422   3 16.409 0.6982 15.726, 71.63 -0.37
BXD53 m 48.89 27.341   5 12.227 0.5592 11.502, 79.02 -0.21
BXD55 m 23.314 10.505   5 4.6979 0.4506 8.55, 33.984 -0.7
BXD6 m 19.254 19.588   3 11.309 1.0173 6.98, 41.844 -0.78
BXD62 m 41.054 15.091   4 7.5455 0.3676 18.68, 50.91 -0.36
BXD63 m 131.1 49.524   5 22.148 0.3776 79.81, 195.1 1.38
BXD64 m 14.295 13.514   3 7.8024 0.9454 4.298, 29.67 -0.88
BXD66 m 21.889 16.564   3 9.563 0.7567 9.4, 40.678 -0.73
BXD67 m 13.908 6.3981   5 2.8613 0.46 6.018, 20.034 -0.89
BXD69 m 154.0 128.0   4 64.02 0.8313 28.802, 320.2 1.82
BXD73 m 45.639 33.874   3 19.557 0.7422 17.636, 83.29 -0.27
BXD75 m 111.7 85.96   4 42.981 0.7695 40.308, 227.6 1.0
BXD77 m 56.48 48.991   5 21.91 0.8674 23.924, 142.0 -0.06
BXD79 m 63.63 35.28   5 15.778 0.5544 23.564, 110.3 0.07
BXD8 m 32.134 6.6864   2   4.728 0.2081 27.406, 36.862 -0.53
BXD81 m 112.2 48.679   5 21.77 0.4338 47.416, 165.8 1.01
BXD84 m 72.92 57.4   5 25.672 0.7872 14.388, 167.6 0.25
BXD87 m 64.12 30.368   4 15.184 0.4736 34.71, 103.4 0.08
BXD89 m 38.618 11.727   5 5.2443 0.3037 25.642, 53.46 -0.41
BXD90 m 35.37 24.373   4 12.187 0.6891 6.6571, 63.48 -0.47
C57BL/6J m 268.7 244.7   2   173.0 0.9109 95.62, 441.7 4.03
DBA/2J m 24.01 12.276   3 7.0875 0.5113 9.862, 31.846 -0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 63.3672 22.1497015104 107.2455880945 19.4888119055
BXD100 m 23.3913333333 16.5094127528 56.0963528408 -9.3136861742
BXD12 m 53.167 24.7641191293 102.2245292612 4.1094707388
BXD27 m 37.5928 22.1497015104 81.4711880945 -6.2855880945
BXD32 m 28.6855 24.7641191293 77.7430292612 -20.3720292612
BXD34 m 19.1 24.7641191293 68.1575292612 -29.9575292612
BXD39 m 46.2853333333 28.5951416911 102.9320887828 -10.3614221162
BXD40 m 41.7515 24.7641191293 90.8090292612 -7.3060292612
BXD43 m 25.556 22.1497015104 69.4343880945 -18.3223880945
BXD45 m 26.8236 22.1497015104 70.7019880945 -17.0547880945
BXD48 m 147.492 22.1497015104 191.3703880945 103.6136119055
BXD48a m 90.3565 24.7641191293 139.4140292612 41.2989707388
BXD49 m 89.294 22.1497015104 133.1723880945 45.4156119055
BXD51 m 40.7076666667 28.5951416911 97.3544221162 -15.9390887828
BXD53 m 48.8904 22.1497015104 92.7687880945 5.0120119055
BXD55 m 23.3144 22.1497015104 67.1927880945 -20.5639880945
BXD6 m 19.254 28.5951416911 75.9007554495 -37.3927554495
BXD62 m 41.054 24.7641191293 90.1115292612 -8.0035292612
BXD63 m 131.144 22.1497015104 175.0223880945 87.2656119055
BXD64 m 14.2946666667 28.5951416911 70.9414221162 -42.3520887828
BXD66 m 21.8886666667 28.5951416911 78.5354221162 -34.7580887828
BXD67 m 13.9082 22.1497015104 57.7865880945 -29.9701880945
BXD69 m 154.0255 24.7641191293 203.0830292612 104.9679707388
BXD73 m 45.6393333333 28.5951416911 102.2860887828 -11.0074221162
BXD75 m 111.7195 24.7641191293 160.7770292612 62.6619707388
BXD77 m 56.4784 22.1497015104 100.3567880945 12.6000119055
BXD79 m 63.6344 22.1497015104 107.5127880945 19.7560119055
BXD8 m 32.134 35.0217531328 101.5118232178 -37.2438232178
BXD81 m 112.2212 22.1497015104 156.0995880945 68.3428119055
BXD84 m 72.9232 22.1497015104 116.8015880945 29.0448119055
BXD87 m 64.1245 24.7641191293 113.1820292612 15.0669707388
BXD89 m 38.618 22.1497015104 82.4963880945 -5.2603880945
BXD90 m 35.370025 24.7641191293 84.4275542612 -13.6875042612
C57BL/6J m 268.66 35.0217531328 338.0378232178 199.2821767822
DBA/2J m 24.0096666667 28.5951416911 80.6564221162 -32.6370887828




  GWAS USING LINEAR MIXED MODELS