Project measure / variable:   Schoonjans1   TDCA_plasma_t60_CD

ID, description, units MPD:112744   TDCA_plasma_t60_CD   plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means53.63   ng/mL
Median of the strain means45.171   ng/mL
SD of the strain means± 39.528
Coefficient of variation (CV)0.7371
Min–max range of strain means0.484   –   153.9   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 243176.6668 7152.2549 3.105 < 0.0001
Residuals 126 290240.2236 2303.4938


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 85.33 40.157   5 17.959 0.4706 35.384, 139.9 0.8
BXD100 m 36.096 11.678   5 5.2226 0.3235 23.774, 54.43 -0.44
BXD11 m 46.13 19.32   4 9.6598 0.4188 22.622, 65.96 -0.19
BXD12 m 15.723 5.1199   3 2.956 0.3256 11.24, 21.302 -0.96
BXD27 m 42.989 46.819   4 23.409 1.0891 14.006, 112.6 -0.27
BXD32 m 61.99 43.184   5 19.312 0.6966 17.906, 133.6 0.21
BXD34 m 6.9924 2.3677   5 1.0589 0.3386 3.948, 9.612 -1.18
BXD39 m 7.6987 1.7637   3 1.0183 0.2291 6.038, 9.55 -1.16
BXD40 m 28.466 11.405   4 5.7026 0.4007 15.076, 42.916 -0.64
BXD43 m 12.549 12.354   7 4.6695 0.9845 3.032, 36.994 -1.04
BXD45 m 66.86 25.007   4 12.504 0.374 36.64, 95.48 0.33
BXD48 m 133.3 120.1   5 53.69 0.9009 45.138, 335.5 2.02
BXD48a m 90.61 87.87   4 43.933 0.9697 13.716, 178.5 0.94
BXD49 m 69.54 59.87   5 26.773 0.8609 18.268, 172.1 0.4
BXD51 m 23.207 8.6209   5 3.8554 0.3715 9.106, 30.726 -0.77
BXD53 m 53.94 29.829   4 14.915 0.5531 21.08, 86.1 0.01
BXD55 m 44.212 21.243   5 9.5004 0.4805 22.848, 75.43 -0.24
BXD6 m 0.484 0.0   1   0.0 0.0 0.484, 0.484 -1.34
BXD62 m 48.959 30.558   5 13.666 0.6242 24.988, 99.09 -0.12
BXD63 m 99.27 76.64   4 38.32 0.772 26.888, 166.5 1.15
BXD64 m 15.039 9.8525   5 4.4062 0.6551 5.236, 29.088 -0.98
BXD66 m 25.131 8.9249   5 3.9913 0.3551 13.908, 33.608 -0.72
BXD67 m 9.343 11.055   4 5.5277 1.1833 0.224, 24.478 -1.12
BXD69 m 75.6 15.041   5 6.7267 0.199 50.65, 88.52 0.56
BXD73 m 112.0 87.5   4 43.749 0.7811 21.048, 217.7 1.48
BXD75 m 116.0 130.1   5 58.16 1.1214 42.648, 347.5 1.58
BXD77 m 15.279 4.4138   5 1.9739 0.2889 8.366, 19.706 -0.97
BXD79 m 95.99 62.28   5 27.851 0.6488 8.634, 178.8 1.07
BXD8 m 36.37 22.255   5 9.9526 0.6119 21.256, 75.42 -0.44
BXD81 m 31.424 15.127   3 8.7334 0.4814 14.684, 44.112 -0.56
BXD84 m 85.95 33.816   5 15.123 0.3934 38.744, 123.0 0.82
BXD87 m 90.12 33.811   5 15.121 0.3752 64.57, 139.5 0.92
BXD89 m 55.85 48.618   5 21.743 0.8705 12.772, 137.9 0.06
BXD90 m 12.409 6.2113   5 2.7778 0.5005 6.43, 20.75 -1.04
C57BL/6J m 153.9 55.64   5 24.882 0.3616 94.47, 211.3 2.54
DBA/2J m 25.832 24.36   4 12.18 0.943 7.858, 60.69 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 85.3268 21.4638945108 127.8032162412 42.8503837588
BXD100 m 36.0956 21.4638945108 78.5720162412 -6.3808162412
BXD11 m 46.13 23.9973635941 93.6200770779 -1.3600770779
BXD12 m 15.7226666667 27.7097686617 70.5594842362 -39.1141509029
BXD27 m 42.98925 23.9973635941 90.4793270779 -4.5008270779
BXD32 m 61.9916 21.4638945108 104.4680162412 19.5151837588
BXD34 m 6.9924 21.4638945108 49.4688162412 -35.4840162412
BXD39 m 7.6986666667 27.7097686617 62.5354842362 -47.1381509029
BXD40 m 28.4665 23.9973635941 75.9565770779 -19.0235770779
BXD43 m 12.5488571429 18.1403017689 48.4479810547 -23.350266769
BXD45 m 66.86 23.9973635941 114.3500770779 19.3699229221
BXD48 m 133.2616 21.4638945108 175.7380162412 90.7851837588
BXD48a m 90.6095 23.9973635941 138.0995770779 43.1194229221
BXD49 m 69.536 21.4638945108 112.0124162412 27.0595837588
BXD51 m 23.2068 21.4638945108 65.6832162412 -19.2696162412
BXD53 m 53.935 23.9973635941 101.4250770779 6.4449229221
BXD55 m 44.2116 21.4638945108 86.6880162412 1.7351837588
BXD62 m 48.9588 21.4638945108 91.4352162412 6.4823837588
BXD63 m 99.2745 23.9973635941 146.7645770779 51.7844229221
BXD64 m 15.0392 21.4638945108 57.5156162412 -27.4372162412
BXD66 m 25.1308 21.4638945108 67.6072162412 -17.3456162412
BXD67 m 9.343 23.9973635941 56.8330770779 -38.1470770779
BXD69 m 75.602 21.4638945108 118.0784162412 33.1255837588
BXD73 m 112.0245 23.9973635941 159.5145770779 64.5344229221
BXD75 m 115.9796 21.4638945108 158.4560162412 73.5031837588
BXD77 m 15.2788 21.4638945108 57.7552162412 -27.1976162412
BXD79 m 95.9908 21.4638945108 138.4672162412 53.5143837588
BXD8 m 36.3696 21.4638945108 78.8460162412 -6.1068162412
BXD81 m 31.424 27.7097686617 86.2608175696 -23.4128175696
BXD84 m 85.9508 21.4638945108 128.4272162412 43.4743837588
BXD87 m 90.124 21.4638945108 132.6004162412 47.6475837588
BXD89 m 55.8504 21.4638945108 98.3268162412 13.3739837588
BXD90 m 12.4092 21.4638945108 54.8856162412 -30.0672162412
C57BL/6J m 153.854 21.4638945108 196.3304162412 111.3775837588
DBA/2J m 25.8315 23.9973635941 73.3215770779 -21.6585770779




  GWAS USING LINEAR MIXED MODELS